The Systems Biology for Infectious Diseases Research Programs develop and validate predictive models of infectious disease initiation, progression, and outcomes.
These models are derived from the study of the architecture and dynamics of systems-wide host/pathogen molecular interaction networks during infection, using integrated datasets generated from a combination of “omics” technologies. The research findings will provide a deeper understanding of the overall complexity of the biological, biochemical, and biophysical molecular processes within microbial organisms as well as their interaction with the host.
The programs provide data and reagents that result from the research conducted and provide training for the broader infectious disease scientific community to promote the use of the systems biology approach.
General infectious disease systems biology research is carried out by
Systems biology work specific to antibacterial resistance is carried out by
Data and software generated by program participants will be made available through publicly accessible Web and database sites, including the NIAID Bioinformatics Resource Centers.
Reagents will be made available through the program participants listed above.
Training in systems biology and “omics” technologies may be provided by the participants. Please contact individual participating sites for information regarding training opportunities
Last Updated April 20, 2016