Comparative Medicine Branch Veterinary Pathology
Mouse Antigens
CD45R: Lymph Node, Peyer's Patch, Spleen
Lymph Node
Mouse mesenteric lymph node -CD45R (B220)+ cortical B-cell follicles and medullary cords.

Peyer's Patch
Mouse CD45R early follicular lymphoma in Peyer’s patch of the small intestine showing disruption of normal CD45R expression pattern and enlargement of the patch.

Spleen
Mouse splenic CD45R in several white pulp areas, in follicles and marginal zone.

Mouse splenic CD45R (B220) shows a white pulp area with many positive B-cells in a follicle, marginal zone and red pulp.

Mouse spleen with CD45R expression on cell membranes of B-cell follicular lymphoma cells in various stages of differentiation.

Mouse spleen - CD45R in early nodular follicular lymphoma in one white pulp area, showing loss of normal white pulp expression pattern of CD45R.

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