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Laboratory of Allergic Diseases

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Melody C. Carter, M.D.

Photo of Melody C. Carter, M.D.

Staff Clinician, Mast Cell Biology Section, LAD

Major Areas of Research

  • Anaphylaxis
  • Pediatric mastocytosis
 

Program Description

Research on anaphylaxis focuses on improving management and coordinating clinical studies with basic research on the responsiveness of human mast cells.

The pediatric mastocytosis studies evaluate children with systemic mastocytosis to determine the natural history and pathogenesis of the disease, as well as parameters associated with increased morbidity.

Biography

Dr. Carter received her M.D. from Tulane University Medical School and completed her pediatric residency training at Emory University in Atlanta. She started her career in general pediatrics in an inner-city clinic. Dr. Carter was an assistant professor on the clinical faculty at Emory University for 12 years, with the final 5 years including clinical research in pediatric allergic diseases. She completed her allergy/immunology fellowship at the National Institutes of Health in 2001 and recently joined the Laboratory of Allergic Diseases as a staff physician.

Memberships

  • American Academy of Pediatrics
  • American Academy of Allergy, Asthma & Immunology
  • National Medical Association

Selected Publications

Carter MC, Metcalfe DD, Komarow HD. Mastocytosis. Immunol Allergy Clin North Am. 2014 Feb;34(1):181-96.

Valent P, Akin C, Arock M, Brockow K, Butterfield J, Carter M, Castells M, Escribano L, Hartmann K, Lieberman P, Nedoszytkok B, Orfaol A, Schwartz L, Sotlar K, Spera W, Triggianio M, Valenta R, Horny HP, Metcalfe D. Definitions, criteria, and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol. 2012;157(3):215-25.

Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 2011 Mar 31;117(13):3629-40.

Wilson TM, Maric I, Simakova O, Bai Y, Chan EC, Olivares N, Carter M, Maric D, Robyn J, Metcalfe DD. Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis. Haematologica. 2011 Mar;96(3):459-63.

Uzzaman A, Maric I, Noel P, Kettelhut BV, Metcalfe DD, Carter MC. Pediatric-onset mastocytosis: a long term clinical follow-up and correlation with bone marrow histopathology. Pediatr Blood Cancer. 2009 Oct;53(4):629-34.

Carter MC, Uzzaman A, Scott LM, Metcalfe DD, Quezado Z. Pediatric mastocytosis: routine anesthetic management for a complex disease. Anesth Analg. 2008 Aug;107(2):422-7.

Visit PubMed for a complete publication listing.

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Last Updated May 21, 2014