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Contact Info

Arnold S. Kirshenbaum, M.D.
Building 10, Room 11C210
10 Center Drive
Bethesda, MD 20892-1881
Phone: 301-496-8495
Fax: 301-480-8384
Email: akirshenba@niaid.nih.gov

See Also

Laboratory of Allergic Diseases

Photo of Arnold S. Kirshenbaum, M.D.

Arnold S. Kirshenbaum, M.D.

Adjunct Investigator, Mast Cell Biology Section

Major Areas of Research

  • Mast cell growth and differentiation from progenitor cells
  • Regulation of normal and neoplastic mast cell growth
  • Systemic mast cell disorders
  • Role of mast cells in disorders with single gene defects

Biography

Dr. Kirshenbaum received his M.D. at Georgetown University in Washington, DC. He did an internship and residency in pediatrics at the Naval Regional Medical Center affiliated with the University of California, San Francisco. Dr. Kirshenbaum trained in allergy and immunology during a fellowship at NIAID and is currently an adjunct investigator in the Laboratory of Allergic Diseases, NIAID. Dr. Kirshenbaum also practices adult and pediatric allergy and immunology in offices in Glen Burnie and Bowie, MD.

Memberships

  • American Academy of Allergy, Asthma & Immunology (Fellow)
  • American Academy of Pediatrics, Maryland Chapter

Selected Publications

Rådinger M, Jensen BM, Kuehn HS, Kirshenbaum A, Gilfillan AM. Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood.Curr Protoc Immunol. 2010 Aug; Chapter 7: Unit 7. 37.

Sundstrom JB, Hair GA, Ansari AA, Secor WE, Gilfillan AM, Metcalfe DD, Kirshenbaum AS. IgE-FcepsiolonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cellsJ Immunol. 2009 May 15;182(10):6401–9.

Kirshenbaum AS, Swindle E, Kulka M, Wu Y, Metcalfe DD. Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition. BMC Immunol. 2008 Aug 7;9:45.

Maric I, Robyn J, Metcalfe DD, Fay MP, Carter M, Wilson T, Fu W, Stoddard J, Scott L, Hartsell M, Kirshenbaum A, Akin C, Nutman TB, Noel P, Klion AD. KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entitiesJ Allergy Clin Immunol. 2007 Sep;120(3):680-7.

Sundstrom JB, Ellis JE, Hair GA, Kirshenbaum AS, Metcalfe DD, Yi H, Cardona AC, Lindsay MK, Ansari AA. Human tissue mast cells are an inducible cellular reservoir of persistent HIV infectionBlood. 2007 Jun 15;109(12):5293-300.

Kushnir-Sukhov NM, Brown JM, Wu Y, Kirshenbaum AS, Metcalfe DD. Human mast cells are capable of serotonin synthesis and releaseJ Allergy Clin Immunol. 2007 Feb;119(2):498-9.

Visit PubMed for a complete publication listing.

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Last Updated March 06, 2012