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Laboratory of Immunogenetics

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Figure 1

Figure 1: Development of systemic autoimmune disease in FcyRIIB-/-

Figure 2

Autoantibodies in serum of FcγRIIB-/- mice

Figure 2a Figure 2b: Nucleolar staining in FcyRII-/- Figure 2c
Nuclear staining with FcγRII-/- Nucleolar staining in FcγRII-/- Yaa no staining in WT

Figure 3

A. FISH analysis of mouse embryonic fibroblasts reveals that the Tlr7 gene (green) is found on both X and Y chromosomes of Yaa mutant mice but only on the X in wildtype B6 animals.
B-C. Close-up and scheme showing the presence of a 4-Mb X chromosome interval in the Y chromosome of Yaa cells.
Figure 3

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Last Updated December 14, 2006