Resources for Researchers

Resources for Researchers

On this page:

• Inter-Division Programs
• Division of Acquired Immunodeficiency Syndrome (DAIDS)
• Division of Allergy, Immunology, and Transplantation (DAIT)
• Division of Intramural Research (DIR)
• Division of Microbiology and Infectious Diseases (DMID)

Inter-Division Programs

• Opportunities and Guidelines to Facilitate Scientific Collaborations
• Bioinformatics
  Provides software developed by the NIAID Office of Cyber Infrastructure and Computational Biology for online use or for download; available to the public
• Clinical Research Toolkit
• Tetramer Facility Guide
• Center for Human Immunology, Autoimmunity, and Inflammation
• Partnering With NIAID
  NIAID has long emphasized collaborations with domestic and international partners to advance research on infectious and immunologic diseases; to develop and test new methods of prevention, diagnosis, and treatment; and to accelerate the translation of research findings into medical products. 

Division of Acquired Immunodeficiency Syndrome (DAIDS)

Scientific Literature

• National Library of Medicine Resources
  Variety of resources, links, databases, and general HIV/AIDS information.
• NCBI PubMed
  Journal articles, abstracts, and other related resources.

Clinical Research Support and Tools

• DAIDS HIV Research Counseling and Testing Curriculum in Biomedical HIV Prevention and Treatment Research
  Training curriculum for HIV counselors involved in DAIDS-supported and/or sponsored research. This training is designed to augment counseling training at the local level. It will be available in the DAIDS Learning Management System.
• National Institutes of Health (NIH) Office of Human Subjects Research
  Established to help NIH-funded investigators understand and comply with the ethical principles and regulatory requirements involving human clinical research.
• NIH Bioethics Resources on the Web
  Resources for those interested in bioethics, including education, research involving human participants and animals, medical and healthcare ethics, and the implications of applied genetics and biotechnology.
• Clinicaltrials.gov
  Database of federally and privately supported clinical trials conducted in the United States and around the world.
• NIH & Clinical Research
  General information about NIH clinical research activities.
• NIAID Clinical Research Toolkit
  Designed for NIAID staff and NIAID-funded researchers, this site contains information on clinical research standards, standard protocol templates, Good Clinical Research Practices training, clinical research databases, and policies and standard operating procedures.
• DAIDS Clinical Research Policies and Standard Procedure Documents
  Set of additional clinical research policies and procedures required for all human subjects research funded by DAIDS.
• Clinical Guidelines for Treating and Preventing HIV/AIDS
  Federally-approved guidelines and information about the current treatment regimens and prevention strategies for HIV infection and AIDS-related illnesses for adults, adolescents, children, and infants.
• AIDSinfo
  Operated by the U.S. Department of Health and Human Services; contains information on HIV/AIDS-related health topics, treatment and prevention guidelines, approved and investigational HIV/AIDS drugs, vaccine research, and clinical trials.
• Center for AIDS Research (CFAR) Network of Integrated Clinical Systems
  Provides integrated clinical data from the large and diverse population of HIV-infected people in the modern HAART era who are receiving care at one of the many U.S. federally-funded CFAR sites; data to address the challenging and rapidly evolving issues in HIV care and research.

Lab Research Tools

• NINDS Regional Brain and Biospecimen Repositories
  List of brain and biospecimen repositories for the study of many neurological diseases and disorders.
• National NeuroAIDS Tissue Consortium
  Established in 1998 to collect, store, and distribute samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals to bolster research on the effects of HIV infection on human brain.
• NIAID Resources for Evaluating New Technologies for Monitoring HIV-infected Patients
  Outlines criteria and procedures for submitting requests to use resources for evaluating new technologies that monitor HIV-infected patients
• NIH Tetramer Facility Guide
  Provides custom synthesis and distribution of soluble MHC-peptide tetramer and CD1d tetramer reagents that can be used to stain antigen-specific T cells.
• Los Alamos HIV Drug Resistance Database
  Comprehensive information on HIV gene mutations that confer resistance to anti-HIV drugs.
• Los Alamos HIV Molecular Immunology Database
  Details comprehensive collection of HIV-1 cytotoxic and helper T-cell epitopes and antibody-binding sites.
• Los Alamos HIV Sequence Database
  Allows users to align and analyze HIV and SIV sequences by nucleotide, amino acid, or viral subtype using special tools and interfaces.
• Los Alamos Nonhuman Primate HIV/SIV Vaccine Trials Database
  Contains information about vaccine studies using SIV and HIV in nonhuman primates.
• DAIDS HIV/AIDS Specimen Repository
  Information on how to gain access to biological materials maintained at DAIDS specimen repositories.
• DAIDS HIV/OI/TB Therapeutics Database
  Collection of compounds and testing data for potential inhibitors of HIV, associated opportunistic infections (OIs), and selected viruses of medical importance.
• NIAID HIV Protein Interaction Database
  Provides a summary of all known interactions of HIV proteins with host cell proteins, other HIV proteins, or proteins from disease organisms associated with HIV/AIDS
• National Center for Research Resources (NCRR)
  NCRR, part of NIH, provides lab scientists and clinical researchers with tools and training resources; includes information about the National Primate Research Centers and nonhuman primate research.
• NCI AIDS and Cancer Specimen Resource
  Funded by the National Cancer Institute (NCI), provides tissue and biological samples to researchers working in HIV/AIDS, cancer, virology, immunology, and other fields.
• NIAID Resource Guide for the Development of AIDS Therapies and Topical Microbicides
  Contains information about NIAID-funded contracts and grant mechanisms to help investigators develop therapies for HIV and its co-infections and microbicide-based HIV prevention strategies.
• NIAID Simian Vaccine Evaluation Units
  Resources for evaluating promising SIV and HIV vaccines in nonhuman primates.
• National Disease Research Interchange (NDRI)
  Partly funded by NIAID and other NIH institutes, NDRI collects, distributes, and maintains a repository of human cells, tissues, and organs for research and transplant purposes. Qualified researchers may register for sample access and view their catalog of services on this site.
• NIAID Preclinical Master Contract
  NIAID’s preclinical master contract offers resources designed to facilitate preclinical development of promising HIV vaccine candidates.
• DAIDS Guidelines for Requesting Access to Animal Models and Vaccine Reagents
  Outlines criteria and procedures for submitting requests for resources to be used for HIV vaccine development.
• DAIDS Vaccine Reagent Resource
  Provides reagents, resources, and quality assurance/quality control analysis of specific reagents used in HIV vaccine development.
• NIH AIDS Research and Reference Reagent Program
  Provides state-of-the-art biological and chemical materials for the study of HIV and related opportunistic pathogens to registered users worldwide at no cost.
• InnateDB
  Publicly available database of the genes, proteins, experimentally-verified interactions, and signaling pathways involved in the innate immune response of humans and mice to microbial infection.
• ImmGen
  The Immunological Genome Project Web database provides gene expression profiles and genetic regulatory networks for a very large array of cell populations in the innate and adaptive immune systems.

Research Training

• Research and Training Opportunities at NIH
  List of research and training opportunities at the NIH campus.
• AIDS International Training and Research Program (AITRP)
  Sponsored by NIH’s Fogarty International Center, AITRP is a program that supports HIV/AIDS-related research training in low- and middle-income countries designed to strengthen HIV-related research and public health capacities in those countries.

Division of Allergy, Immunology, and Transplantation

• Center for International Blood & Marrow Transplant Research
• dbMHC, the NCBI database for DNA and clinical data related to the human major histocompatibility complex
• Gene Knockout/Transgenic Mice NIAID Exchange Program
• Immune Epitope Database and Analysis Resource
• Immunology Database and Analysis Portal (ImmPORT)
• Modeling Immunity for Biodefense
• Multiple Autoimmune Disease Genetics Consortium (MADGC)
• Mutant Mouse Regional Resource Center
• National Swine Research and Resource Center (NSRRC)
• NIAID Bioinformatics Integration Support Contract (BISC)
• NIH Nonhuman Primate Reagent Resources
• Non-Obese Diabetic (NOD) Mouse BAC Library
• Primary Immunodeficiency Disease DNA and Cell Repository
• Primary Immunodeficiency Disease Registry
• Severe Chronic Neutropenia International Registry (SCNIR)
• Severe Chronic Neutropenia Tissue Bank (Repository)
• Systems Approach to Immunology

Division of Intramural Research

• Database of Human HIES Mutations (STAT3base)
• Transgenic and Gene-Targeted Mice Repository
• International Collaborative Network for the Study of Human Helminth Co-infections
• North American Cysticercosis Consortium

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