Dr. Alison Yao
This month's highlight is from a Vibrio cholerae toxin. The gastrointestinal pathogen V. cholerae is the bacteria responsible for causing cholera in humans.
Its Multifunctional Autoprocessing Repeats-in-ToXin toxin (MARTX) is related to other bacterial toxins, including those produced by at least 9 different Gram-negative bacteria, such as emerging hospital-acquired infections due to Clostridium difficile.
Information for researchers about the toxin protease structure can be found at the CSGID structure summary.
Last Updated March 02, 2011