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Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naïve HIV-Infected Patients
The National Institutes of Health is conducting a research study to evaluate volunteers either at the acute (early signs and symptoms of HIV infection and/or less than four months of known HIV exposure) and chronic stage (greater than six months or determinate positive result) of HIV-infection, who have elected to begin antiretroviral therapy (ART). The ART is to be provided by participant's Primary Care Provider. The study will require that patients consent to leukapheresis once before antiretroviral therapy and several times after suppression of plasma viremia (when the viral load is <50). We hope to further understand the mechanism(s) involved in maintenance of immune function following early intervention with ART.
We will collect white blood cells by a process called leukapheresis, a standard blood collection procedure. Leukapheresis will remove white cells first, and then replace the red cells, through the same needle, or through a needle in your other arm. Volunteers will be compensated.
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Last Updated October 26, 2011