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NIAID HIV and Emerging Infectious Diseases Program

Healthy Volunteer Studies

Studies of healthy volunteers are crucial to the understanding and treatment of diseases. They provide a baseline for measuring the extent of disease and provide important information about the safety and effectiveness of various treatments.

A Pilot Study for Collection of Anti-Influenza A H1N1 (Swine Flu) Hyper-immune Plasma

(HIPP – Protocol #09-I-0226)

We will recruit 200 subjects, healthy individuals between 18 and 60 years of age who are eligible to donate blood. Individuals must have previously either recovered from novel H1N1 influenza or have been vaccinated against the infection. Eligible participants will undergo apheresis, an outpatient procedure in which researchers will collect plasma containing antibodies against the influenza virus by drawing blood into a special machine that separates blood cells from the liquid portion under sterile conditions and then returns the blood cells to the donor. Volunteers will be compensated.

Phase 1 Study of Safety and Immunogenicity of AD4-H5-VTN in AD4 Seronegative Volunteers

(SAMOSA – Protocol #11-I-0259)

We will recruit 68 subjects (and up to 68 of their close, household contacts) who are healthy individuals between 18 and 49 years of age; if you have a household contact participating, they must be between the ages of 18 and 65. Volunteers must be in good general health, and be willing to receive a live influenza vaccine. Volunteers must also be willing to spend 7 days hospitalized at the NIH, and to return for at least six visits up to 12 months following vaccination. Volunteers will be compensated.

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Last Updated October 26, 2011