Volunteer for a Clinical Study

Healthy volunteers are people with no known significant health problems. They often are given the same tests, procedures, or drugs as patient volunteers so that researchers can compare results and make new discoveries. Healthy volunteers may be compensated for their time and travel.

The following are selected studies being conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland. The links lead to full study titles and descriptions.

A Pilot Study for Collection of Anti-Influenza A H1N1 (Swine Flu) Hyper-immune Plasma (NCT00984451)
The goal of this study is to collect antibodies from people who have received the flu vaccine in order to develop an antibody-based treatment for the disease.

Evaluation of Tissue-Specific Immune Responses (NCT01132859)
This study is enrolling healthy volunteers at least 18 years of age who agree to donate specimens for research purposes. The objective of this study is to evaluate blood and other tissue samples for immune responses to vaccines and natural infections.

Immune Responses to Two Experimental HIV Vaccines in Healthy Adults (NCT01386489)
This study is enrolling healthy volunteers ages 18 to 50 who are not infected with HIV and meet the eligibility requirements. The purpose of this study is to analyze the body’s immune responses to the experimental HIV vaccines and to assess the vaccines’ safety.

Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female Transgender Persons Who Have Sex With Men (NCT00865566)
The purpose of this study is to determine the safety and effectiveness of a specific vaccine regimen in healthy, circumcised men and male-to-female transgender persons who have sex with men.

Screening Healthy Volunteers for Influenza Challenge Studies (NCT01386424)
This study is enrolling healthy volunteers ages 18 to 50 who are non-smokers or non-habitual smokers to determine eligibility for future studies on the development and course of the flu virus.

Screening of Volunteers for Vaccine Clinical Trials (NCT01375530)
This study is enrolling healthy volunteers ages 18 to 70 to screen for clinical trials that will allow researchers to study vaccines and injection devices.

Screening Protocol for HIV Vaccine Studies (NCT00031304)
This study is enrolling healthy volunteers ages 18 to 60 to test a vaccine against HIV, the virus that causes AIDS.

Study of AD4-H5-VTN Vaccine in Healthy Volunteers (NCT01443936)
This study is enrolling healthy volunteers ages 18 to 45 to see if an adenovirus vaccine called AD4-H5-VTN produces a strong enough immune response to be used as part of vaccines to prevent diseases such as malaria or HIV. Because the vaccine may cause cold symptoms, members of the volunteer’s household must take part in the study.

Don’t live in the Washington, DC, area? See NIAID-supported clinical research studies enrolling healthy volunteers being conducted across the United States and around the world.