The Division of Acquired Immune Deficiency Syndrome (DAIDS) was formed in 1986 to develop and implement the national research agenda to address the HIV/AIDS epidemic. Specifically, the mission of DAIDS is to help ensure an end to the HIV/AIDS epidemic by increasing basic knowledge of the pathogenesis and transmission of the human immunodeficiency virus (HIV), supporting the development of therapies for HIV infection and its complications and co-infections, and supporting the development of vaccines and other prevention strategies. DAIDS accomplishes this through planning, implementing, managing, and evaluating programs through the following research programs and offices:
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Basic Sciences Program (BSP)
Basic science research efforts by NIAID-funded investigators have yielded important scientific contributions, including new targets for vaccines, drugs, and microbicides. The BSP, consisting of the Pathogenesis and Basic Research Branch, Targeted Interventions Branch and Epidemiology Branch, supports a major component of NIAID HIV/AIDS basic research efforts by carrying out the following activities:
For information on NIAID basic science research efforts, visit HIV Basic Science Research.
Therapeutics Research Program (TRP)
The evaluation of new drugs and therapeutic agents is a critical aspect of NIAID’s therapeutic research agenda. NIAID-sponsored therapeutics research has already had a dramatic impact on our understanding of the pathogenesis and clinical management of HIV infection over the last decade, and has helped define international guidelines for the treatment of primary HIV infection in adults and children and associated opportunistic infections and prophylactic regimens for these secondary infections, identify biological markers for predicting a drug's effectiveness and disease progression, and set the standard for use of antiretroviral drugs for preventing mother-to-infant transmission.
The TRP, which is divided into four branches: Drug Development and Clinical Sciences Branch, HIV Research Branch, Complications and Co-Infections Research Branch, and the Pediatric Medicine Branch, carries out the following therapeutic research activities:
For more information on NIAID therapeutic research efforts, visit HIV/AIDS Therapeutics Research.
Vaccine Research Program (VRP)
The discovery and development of an HIV/AIDS vaccine for the prevention of HIV infection is one of the top priorities at NIAID. As such, the VRP, which is divided into the Preclinical Research and Development Branch and Vaccine Clinical Research Branch, supports basic, preclinical, and clinical research of candidate vaccines through the following activities:
For more information on NIAID HIV vaccine research efforts, visit HIV/AIDS Vaccine Research.
Prevention Sciences Program (PSP)
The development of new and more effective non-vaccine methods and strategies to prevent HIV infection is an important component of NIAID’s HIV research agenda. DAIDS supports research on biomedical and behavioral prevention approaches through the Prevention Sciences Program (PSP), which includes the Microbicide Research Branch and the Prevention Research Branch, that carries out the following activities:
For more information about NIAID HIV prevention research efforts, visit HIV/AIDS Prevention Science Research.
Office for Policy in Clinical Research Operations (OPCRO)
The OPCRO manages and supports DAIDS clinical research and helps ensure compliance with applicable regulations, standards, and good clinical practice guidelines; study participant safety and welfare; and study quality and integrity. OPCRO, which includes the Clinical Research Resources Branch, Human Subjects Protection Branch, Policy, Training, and Quality Assurance Branch, Regulatory Affairs Branch, Pharmaceutical Affairs Branch, Clinical Trials Agreements Team, and Safety and Pharmacovigilance Team, carries out the following key functions:
Scientific Communications and Information Branch (SCIB)
The SCIB oversees the communications, reporting, and other operations for DAIDS by performing the following key functions:
Scientific Planning and Operations Branch (SPOB)
The SPOB oversees the long and short term planning, budget, and scientific and administrative activities for DAIDS by performing the following key functions:
Office of Clinical Site Oversight (OCSO)
The OCSO facilitates the clinical research of the DAIDS scientific programs by overseeing clinical sites associated with the NIAID-sponsored HIV/AIDS clinical trials networks. As such, they perform the following key functions:
Last Updated March 17, 2014