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Biostatistics Research Branch (BRB)

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Claire W. Hallahan, M.S.

Mathematical Statistician

Additional Information

Curriculum Vitae (PDF)

Recent Publications

Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C, O'Shea MA, Mican J, Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM, Mellors JW, Hallahan CW, Follman DA, Connors M. Lytic Granule Loading of CD8(+) T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control. Immunity. In press Dec 2008

Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, Hallahan CW, Migueles SA, Wrammert J, Ahmed R, Nason M, Wyatt RT, Mascola JR, Connors M.Frequency and Phenotype of HIV Envelope-specific B Cells From Patients With Broadly Cross-Neutralizing Antibodies. J Virol. In press Dec 2008

Chun TW, Nickle DC, Justement JS, Meyers JH, Roby G, Hallahan CW, Kottilil S, Moir S, Mican JM, Mullins JI, Ward DJ, Kovacs JA, Mannon PJ, Fauci AS. Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis. Vol 197: (5) 714-20, 2008

Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S, Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro. J Virol. Vol 82: (8) 3997-4006, 2008

Kottilil S, Jackson JO, Reitano KN, O’Shea MA, Roby G, Lloyd M, Yang J, Hallahan CW, Rehm CA, Arthos J, Lempicki R, Fauci AS. Innate immunity in HIV infection – Enhanced susceptibility to CD9S-mediated natural killer cell death and turnover induced by HIV viremia. JAIDS-Journal of Acquired Immune Deficiency Syndromes. Vol 46: (2) 151-159, 2007

Myers JH, Justement JS, Hallahan CW, Blair ET, Sun YA, OShea MA, Roby G, Kottilil S, Moir S, Kovacs CM, Chun TW, Fauci AS. (2007) Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLos ONE 2007 2(5): e458. doi:10,1371/ Journal.pone.0000458

Chun TW, Justement JS, Moir S, Hallahan CW, Maenza J, Mullins JI, Collier AC, Corey L, Fauci AS. Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: Implications for eradication of virus. J Infect Dis. Vol 195: (12) 1762-1764, 2007

Tilton JC, Luskin MR, Johnson AJ, Manion M, Hallahan CW, Metcalf JA, McLaughlin M, Davey RT, Connors M. Changes in paracrine interleukin-2 requirement, CCR7 expression, frequency, and cytokine secretion of human immunodeficiency virus-specific CD4(+) T cells are a consequence of antigen load. J Virol. Vol 81: (6) 2713-2725, 2007

Tilton JC, Johnson AJ, Luskin MR, Manion MM, Yang J, Adelsberger JW, Lempicki RA, Hallahan CW, McLaughlin M, Mican JM, Metcalf JA, Ivasere C, Connors M. Diminished production of monocyte proinflammatory cytokines during human immunodeficiency virus viremia is mediated by type I interferons. J Virol. Vol 80: (23) 11486-11497, 2006

Keh CE, Shen JM, Hahn B, Hallahan CW, Rehm CA, Davey RT, Lane HC, Sereti, I. Interruption of antiretroviral therapy blunts but does not abrogate CD4 T-Cell responses to interleukin-2 administration in HIV infected patients. AIDS. Vol 20: (3) P361-369, 2006

Kottilil S, Shin K, Jackson JO, Reitano KN, O’Shea MA, Yang J, Hallahan CW, Lempicki R, Arthos J, Fauci AS. Innate immune dysfunction in HIV infection: Effect of HIV envelope-NK cell interactions. J Immunol. Vol 176: (2) 1107-1114, 2006

Chun TW, Nickle DC, Justement JS, Large D, Semerjian A, Curlin ME, O’Shea MA, Hallahan CW, Daucher M, Ward DJ, Moir S, Mullins JI, Kovacs C, Fauci AS. HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir. J Clin Invest. Vol 115: (11) 3250-3255, 2005

Dybul M, Nies-Kraske E, Dewar R, Maldarelli F, Hallahan, CW, Daucher M, Piscitelli SC, Ehler L, Weigan A, Palmer S, Metcalf JA, Davey RT, Kress DMR, Powers A, Beck I, Frenkel L, Baseler M, Coffin J, Fauci AS. A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for treatment of chronic HIV infection. J Infect Dis. Vol 189 (11) 1974-1982, 2004

Sereti I, Anthon KB, Martinez-Wilson H, Lempicki R, Adelsberger J, Metcalf JA, Hallahan, CW, Davey RT, Kovacs JA, Lane HC. IL2-Induced CD4+ T cell expansion in HIV-infected patients is associated with decreased T cell proliferation. Blood. Vol 104: (3) 775-780, 2004

Kottilill S, Shin K, Planta M, McLaughlin M, Hallahan CW, Ghany M, Chun TW, Sneller MC, Fauci AS. Expression of chemokine and inhibitory receptors on natural killer cells: Effect of immune activation and HIV viremia. J Infect Dis. 189 (7) 1193-1198, 2004.

Chun TW, Justement JS, Sanford C, Hallahan CW, Planta MA, Loutfy M, Kottilil S, Moir S, Kovacs C, Fauci AS. Relationship between the frequency of HIV-specific CD8(+) T cells and the level of CD38(+)CD8(+) T cells in untreated HIV-infected individuals. Proc Natl Acad Sci. 101 (8): 2464-2469, 2004

All Claire W. Hallahan Publications

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Last Updated March 18, 2007