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2011 NIAID Year In Review

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Innovating for the Discovery of an Effective HIV Vaccine

Identifying safe and effective vaccines to prevent HIV transmission and infection remains one of NIAID’s highest research priorities. Results from early testing of experimental HIV vaccines in humans indicate that identifying highly effective vaccination approaches may prove more elusive than anticipated.

In 2008, NIAID held a vaccine summit to examine the direction of the field and gather input on how to reinvigorate efforts to develop an effective HIV vaccine. One strong recommendation was to invest substantially in fostering new discoveries that improve understanding of the immune responses that are most relevant for preventing HIV infection, and novel approaches for generating those responses. Even with the modest success of a recent HIV vaccine efficacy trial, this type of research is essential.

To encourage progress in this area, in FY 2011 NIAID issued the initiative Innovation for HIV Vaccine Discovery to solicit proposals for innovative, unconventional research to identify novel vaccine concepts and targets that will aid in the design and development of an effective vaccine to prevent HIV infection. Through this program, NIAID aims to support innovative ideas, new investigators, and new interdisciplinary collaborations that may have a substantial impact on approaches to HIV/AIDS vaccine discovery and development.

Last Updated December 28, 2012

Last Reviewed December 28, 2012