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Decipher the Complex Responses of the Immune System to Infection or Vaccination Using a Systems Biology Approach

A systems biology approach combines computational and experimental methods to analyze, model, and predict the interactions among components of complex biological systems. This approach is well suited to studying the complex networks of cells and molecules that are crucial for effective immune responses.

In FY 2011, NIAID invited researchers to participate in the Systems Approach to Immunity and Inflammation program. This collaborative, multidisciplinary program will bring together investigators with expertise in immunology, mouse genetics, proteomics, infectious disease, bioinformatics, and computational science. Researchers will use a systems biology approach to understand immune responses to infection and vaccination, with a focus on emerging and re-emerging infectious diseases identified by NIAID as being of concern to human health. The knowledge gained by understanding these dynamic networks will provide insights into how the immune system responds to microbial threats and contribute to the development of improved vaccines and therapies to defend against those threats.

Last Updated January 08, 2013

Last Reviewed January 08, 2013