The Infectious Disease Pathogenesis Section provides molecular and necropsy support to NIAID investigators and programs that conduct research involving animals. Our veterinary pathologists have expertise in the gross and microscopic evaluation of both spontaneous and experimental disease and provide guidance on the design, conduct, interpretation, and publication of studies involves laboratory animals.
Ian Moore, D.V.M., Ph.D., Veterinary PathologistMahnaz Minai, HistotechnologistKevin Bock, Histotechnologist
Contact Dr. Ian Moore by email or phone with inquiries or questions regarding current or new projects.
7:00 a.m. – 3:30 p.m., Monday–FridayClosed on all federal holidays
Twinbrook III, 2nd FloorOffice: Room 2W-01Lab: Room 2W-03
NIAID/IDPS12735 Twinbrook Parkway, Rm 2W-03Rockville, MD 20892-8134
Boonnak K, Vogel L, Orandle M, Zimmerman D, Talor E, Subbarao K. Antigen-activated dendritic cells ameliorate influenza A infections. J Clin Invest. 2013 Jul 1;123(7):2850-61.
Via LE, Weiner DM, Schimel D, Lin PL, Dayao E, Tankersley SL, Cai Y, Coleman MT, Tomko J, Paripati P, Orandle M, Kastenmayer RJ, Tartakovsky M, Rosenthal A, Portevin D, Eum SY, Lahouar S, Gagneux S, Young DB, Flynn JL, Barry CE 3rd. Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus). Infect Immun. 2013 Aug;81(8):2909-19.
Waisberg M, Lin CK, Huang CY, Pena M, Orandle M, Bolland S, Pierce SK. The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice. PLoS One. 2013 May 10;8(5):e62820.
Yi L, Liu Q, Orandle MS, Sadiq-Ali S, Koontz SM, Choi U, Torres-Velez FJ, Jackson SH. p47(phox) directs murine macrophage cell fate decisions. Am J Pathol. 2012 Mar;180(3):1049-58.
Suguitan AL Jr, Matsuoka Y, Lau YF, Santos CP, Vogel L, Cheng LI, Orandle M, Subbarao K. The multibasic cleavage site of the hemagglutinin of highly pathogenic A/Vietnam/1203/2004 (H5N1) avian influenza virus acts as a virulence factor in a host-specific manner in mammals. J Virol. 2012 Mar;86(5):2706-14.
Shulzhenko N, Morgun A, Hsiao W, Battle M, Yao M, Gavrilova O, Orandle M, Mayer L, Macpherson AJ, McCoy KD, Fraser-Liggett C, Matzinger P. Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med. 2011 Nov 20;17(12):1585-93.
Last Updated October 27, 2014