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David N. Garboczi, Ph.D.

Chief, Structural Biology Unit, RTB

Major Areas of Research

  • Production of large amounts of highly purified, correctly folded macromolecules
  • Preparation diffraction-quality crystals
  • Determination of structures by X-ray crystallography and other macromolecules
 

Program Description

The Structural Biology Unit enables intramural NIAID investigators to use state-of-the-art applications in X-ray crystallography in their research programs. We provide expertise, instruction, and instrumentation in X-ray crystallography of macromolecules. Our staff is available to assist in producing the highly purified macromolecules required for growing crystals, in acquiring X-ray data from the crystals, and in using the X-ray data to determine three-dimensional crystal structures.

Instrumentation

Our facility is equipped with specialized instrumentation dedicated to the science of structural biology, which entails answering biological questions by investigating the structure of macromolecules.

Research Group

David N. Garboczi, Ph.D.
Apostolos G. Gittis, Ph.D.
Daniel Tata, B.S.
Kavita Singh, Ph.D.
Phuc "Jim" Nguyen, B.S.

Last Updated October 31, 2012

Last Reviewed October 31, 2012