Access the SPICE software (ZIP).
Multicolor flow cytometry experiments generate vast amounts of complex data and require sophisticated software for their evaluation. SPICE is a data-mining software application that analyzes large FLOWJO data sets from polychromatic flow cytometry and organizes the normalized data graphically. SPICE enables users to discover potential correlations in their experimental data within complex data sets. Many potential applications for SPICE exist: the software can be used to analyze any multivariate data set for which a series of nominal measurements and a single continuous measurement is available.
This software is provided free of charge by the National Institute of Allergy and Infectious Diseases.
SPICE was developed by the NIAID Office of Cyber Infrastructure and Computational Biology Bioinformatics and Computational Biosciences Branch (OCICB/BCBB) in collaboration with Dr. Mario Roederer, senior investigator of the ImmunoTechnology Section (ITS) of the NIAID Vaccine Research Center. SPICE is currently used in the ITS lab to reveal relationships among numerous T-cell immune responses resulting from vaccine challenges.
Last Updated March 20, 2012
Last Reviewed June 17, 2010