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Bioinformatics Resource Centers (BRCs)

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About

What services are provided?

The Bioinformatics Resource Centers (BRCs) for Infectious Diseases program, a continuation and expansion of a program initiated in 2004, consists of five centers, each specializing in a different group of pathogens. Pathogens include, but are not limited to, those in the NIAID Category A-C Priority Pathogen lists for biodefense research, and pathogens causing emerging/reemerging infectious diseases. The groups of pathogens are:

  • All bacterial species
  • All viral families
  • All eukaryotic pathogen species
  • Invertebrate vectors of human pathogens
  • Influenza virus

Each Center

  • Stores, updates, integrates, and displays the following types of data: genome sequence and annotation, functional genomics, proteomics, metagenomics other “-omics”, epidemiology, surveillance, population genetics, genotype/phenotype association, antimicrobial resistance, antigenic expression, basic, and clinical.
  • Makes available analytical resources, bioinformatics tools, and service
  • s for data analysis.
  • Supplies experimental protocols and other relevant metadata
  • Offers bioinformatics training at the BRC sites or at the requesting institution or laboratory.
  • Partners with infectious disease research communities through the establishment of “Driving Biological Projects” to provide experimental biology laboratories with bioinformatics services.

Where are services provided?

The five Bioinformatics Resource Centers provide data, tools and services related to the above-mentioned groups of pathogens.

In addition, 24-hour annotation services for bacterial genomes and metagenomics datasets are freely available respectively at http://rast.nmpdr.org/ and http://metagenomics.nmpdr.org/.

Access

Data, bioinformatics tools and services provided by the five BRCs are freely and publicly available to the scientific community through user-friendly Web interfaces. The BRCs Pathogen Portal promotes interoperability among the BRCs and with other bioinformatics resources.

The experimental data and information generated by the Driving Biological Projects will also be made accessible to the broad scientific community through the individual BRCs and/or the BRCs Pathogen Portal. Such information is expected to support or improve the annotation of the genome, proteome and metabolome of the targeted pathogens.

Bioinformatics training opportunities are available at no cost upon request to the centers.

As of January 1, 2010, all data and information formerly available through the Administrative Resource Center for Biodefense Proteomics Research website are now available as part of the BRCs Pathogen Portal.

Pathogen Functional Genomics Resource Center (PFGRC) microarray designs, protocols, and software tools are available as part of the BRCs Pathogen Portal. Reagents are available at BEI Resources.

Data Release

Information and Related Resources

Last Updated January 23, 2014