Consider Alternatives to Using Animals
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When planning your research, consider whether you can achieve your
scientific objectives while reducing the number of animals, refining
the use of animals by minimizing their pain or distress, using
a lower order species, or designing your experiments to avoid using
animals at all.
USDA regulations require that investigators search the scientific literature
for alternatives. Conduct this search while
you plan your experiments. Include the search results in the animal
study protocol for your IACUC's
approval.
Considering alternatives during the planning stage gives you enough
time to incorporate methods that benefit the animals and the science.
It also shows peer
reviewers that you are thorough and reduces your chances of
a bar
to award because of animal
welfare concerns.
Limit Animal Use and Discomfort
- Limit animal involvement by using the minimum number required
to obtain valid results.
- Use non-animal methods, such as mathematical models, computer
simulation, or in vitro biological systems.
- Avoid or minimize animal discomfort, distress, and pain as is
consistent with sound scientific practices.
- Use appropriate sedation, analgesia, or anesthesia when your
procedures will cause more than momentary pain or distress. Do
not perform surgical or other painful procedures on non-anesthetized
animals.
- If animals are necessary, select the lowest
phylogenetic species appropriate for the experiment.
Resources
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