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Effect of Vector Innate Immunity and Human-Derived Immune Molecules on the Transmission of Vector-Borne Pathogens

Bethesda, Maryland
May 14-15, 2013

This workshop was the fourth in a series of activities focusing on the topic of how vector factors influence human immune responses to vector-borne pathogens and vice versa. In May 2011 we organized a meeting on the Immunological Consequences of Vector Derived Factors followed by a symposium during the American Society of Tropical Medicine and Hygiene in Philadelphia, PA on December 2011. In May 2012 we convened a workshop focusing on the Role of Immune-Cell Subsets in the Establishment of Vector-Borne Infections.

This fourth event focused on how human immune factors imbibed with a blood meal affect not only the vector but also the pathogens that may be found in the vector; and how the vector microbiome and innate immunity interfere with pathogen development and transmission.

To ensure that the discussions are cross-cutting and stimulating, and that the interactions led to scientific collaborations, we developed a novel format for this meeting. Senior investigators presented talks that provided background information. Senior postdocs or junior faculty presented a hypothetical project that addressed a specific question related to the interaction among the organisms involved in the spread of vector-borne diseases (pathogen and arthropod vector). This hypothetical project not only showcased the young investigator’s expertise and creativity, but also clearly laid out what additional expertise would be required to complete such a multi-disciplinary project.

We anticipate that this format will facilitate the assembly of collaborative research teams as well as generated discussions that may help young investigators initiate a new and independent research program in this field.

Last Updated June 26, 2013