Skip Navigation
Archive

NIAID Archive

Important note: Information on this page was accurate at the time of publication. This page is no longer being updated.
​​
NIH HHS News Release Logo
National Institute of Allergy and
Infectious Diseases (NIAID)
http://www.niaid.nih.gov

FOR IMMEDIATE RELEASE
Monday, June 23, 2003

Media Contact:
Laurie K. Doepel
(301) 402-1663
niaidnews@niaid.nih.gov
Skip Content Marketing
  • Share this:
  • submit to facebook
  • Tweet it
  • submit to reddit
  • submit to StumbleUpon
  • submit to Google +

NIAID Offers “SARS Chip” Free to Researchers

NIAID Partnership with TIGR and Affymetrix Catalyzes SARS Research

To spur research on severe acute respiratory syndrome (SARS), the National Institute of Allergy and Infectious Diseases (NIAID) today announced a free distribution program for a new “SARS chip” that will enable researchers to rapidly detect tiny genetic variations among different SARS virus strains. Today’s announcement is the result of an alliance of government, not-for-profit and industry partners.

NIAID has purchased several hundred SARS microarrays—essentially a reference strain of the SARS coronavirus embedded in a quartz chip—and will distribute the arrays at no cost to qualified researchers worldwide. Distribution of the GeneChip® brand SARS Array, made by Affymetrix, Inc., will be coordinated by the NIAID’s Pathogen Functional Genomics Resource Center (PFGRC). The PFGRC is operated by The Institute for Genomic Research under a contract from NIAID. Any researcher can request the SARS Array using a simple Web-based application process.

“Through this collaboration, NIAID has quickly responded to make this genomic resource widely available to the SARS research community,” says NIAID Director Anthony S. Fauci, M.D. “This powerful tool will help us better understand this newly recognized pathogen and its spread, and will provide new leads in our search for effective SARS countermeasures.”

No vaccine or specific treatments exist for the pneumonia-like disease, which has infected more than 8,400 people and caused about 800 deaths since it emerged for the first time in November 2002.

The new array comprises the 29,700 DNA base pairs of the SARS coronavirus. It was designed using data from research centers in the United States, Canada and Asia that had sequenced the complete genome of the SARS coronavirus. The SARS Array will help scientists achieve a number of objectives:

  • By comparing the genomes of different SARS virus isolates and then using genetic relatedness to group them into subtypes, scientists can construct a “family tree” of the SARS coronaviruses.
  • By comparing clinical outcomes among individuals infected with different SARS virus subtypes, scientists can determine which strains are most dangerous and gain key information for the development of targeted antiviral drugs.
  • Over time, epidemiologists can trace how the virus evolves as it spreads to different populations in different geographic locales.

Details on the application procedure are posted on the NIAID Web site at http://www.niaid.nih.gov/dmid/genomes/pfgrc. The SARS-CoV array program is part of an ongoing effort by NIAID to promote genomics as a vehicle to improve the understanding of disease-causing microbes and the development of diagnostics and other medical tools for them.

In 2001, NIAID awarded a five-year contract to TIGR to establish and operate the PFGRC. The PFGRC is a centralized facility providing the research community with resources and training needed to conduct functional genomics studies on a variety of human pathogens and invertebrate vectors of disease for which genomic sequence information is available.


NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at www.niaid.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

NIH...Turning Discovery Into Health ®

back to top


Archive

NIAID Archive

Important note: Information on this page was accurate at the time of publication. This page is no longer being updated.
​​​​

Last Updated June 23, 2003

Last Reviewed June 23, 2003