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February 15, 2005

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A Statement by the Centers for Disease Control and Prevention (CDC) and the
National Institutes of Health (NIH)
"Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population," by Simonsen et al. (2005)


A study published this week in the Archives of Internal Medicine reports that vaccination of the elderly population against influenza may be less effective in preventing death among the elderly than previously assumed.  This study's findings have caused some confusion about whether people 65 years old and older should receive an influenza vaccination.
 
CDC and NIH continue to support the Advisory Committee on Immunization Practices (ACIP) recommendation that people aged 65 and older get vaccinated against influenza each year.  People aged 65 and older are at highest risk for complications, hospitalizations, and deaths from influenza.  Vaccination remains the best protection from influenza available for people 65 and older and their loved ones.
 
Numerous studies have shown that influenza vaccination works- including to help protect the elderly from serious illness and hospitalizations- but the degree to which it works varies from year to year and can be difficult to measure.  For example, influenza seasons differ each year in length and severity, and the health status of individuals also matters. 
 
In the current study by Simonsen et al, the authors in no way imply that the elderly should not receive influenza vaccine. Rather, the study concludes that the vaccine may prevent fewer deaths among the elderly than previous studies would have suggested.  Therefore, the authors note that there is room for improvement in influenza prevention efforts, including research into developing more effective vaccines for the elderly and the increased use of medicines to treat flu.

In addition, recently published studies raise the possibility that it may be beneficial to vaccinate larger numbers of healthy persons, including children, to prevent transmission of influenza viruses to high-risk persons such as the elderly.

Expansion of groups for whom influenza vaccination is recommended is under discussion by the ACIP and CDC, and is partly contingent on adequate vaccine supply in the future.
 
The CDC and ACIP continually review their influenza vaccine recommendations as well as studies and published research in order to develop the best recommendations for protecting all Americans from influenza.  This study is a reminder that there is room for improvement in how we protect the elderly from influenza, and CDC and NIH encourage research that strengthens our ability to do so.

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Media inquiries can be directed to the NIAID News Office at 301-402-1663, niaidnews@niaid.nih.gov .


NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at www.niaid.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

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NIAID Archive

Important note: Information on this page was accurate at the time of publication. This page is no longer being updated.
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Last Updated February 15, 2005