News from NIAID-Supported Institutions for 2011

Below are links to press releases about NIAID-funded research from some of the institutions we support.

December 2011

Researchers Discover Neutrophils in Spleen When No Infection is Present
Dec. 25, 2011—Hospital del Mar Research Institute

UTSW Research Suggests New Way to Ensure Effectiveness of TB Treatment
Dec. 22, 2011—University of Texas Southwestern Medical Center

Genetics and Immunity Interact in Dengue Disease Severity
Dec. 21, 2011—Broad Institute

Purdue Biologists Identify New Strategy Used by Bacteria During Infection
Dec. 21, 2011—Purdue University

Pathogenic Landscape of HIV: Hundreds of Connections Between Viral and Human Proteins Identified in UCSF-Led Study
Dec. 21, 2011—University of California, San Francisco

Stopping Influenza Evolution Before it Starts
Dec. 20, 2011—MIT

Study Suggests Early ART in Recently HIV-Infected Patients Preferable to Delayed Treatment
Dec. 16, 2011—Infectious Diseases Society of America

Penn Study Shows How B Cells May Generate Antibodies After Vaccination
Dec. 15, 2011—Perelman School of Medicine at the University of Pennsylvania

Soligenix Initiates Next Generation Anthrax Vaccine Development Program under Agreement with Harvard University
Dec. 15, 2011—Soligenix, Inc.

First Molecular Evidence Links Live Poultry Markets to Human H5N1 Infection in China
Dec. 15, 2011—American Society For Microbiology

Breakthrough Offers New Hope in Fight Against Global Pandemic
Dec. 14, 2011—Gladstone Institutes

Work in Cells, Animals, Patients Reveals Toxin’s Role in Asthma
Dec. 14, 2011 — University of Texas Health Science Center at San Antonio

SRI International Awarded Contract Worth Up to $100M from National Institute of Allergy and Infectious Diseases
Dec.14, 2011 — SRI International

"Pep Talk" Can Revive Immune Cells Exhausted by Chronic Viral Infection
Dec. 13,  2011—Emory Vaccine Center

New Discovery on How the Body Fights Dengue Fever
Dec. 12, 2012—American Society For Microbiology

Improved Medication Use Could Reduce Severe Asthma Attacks
Dec. 12, 2011—Henry Ford Hospital

Engaging in the Enterprise of Invention at Princeton
Dec. 12, 2011—Princeton University

New Finding Clears Malaria
Dec. 12, 2011—University of Iowa

Changing the Locks: HIV Discovery Could Allow Scientists to Block Virus’s Entry into Cell Nucleus
Dec. 9, 2011—Wellcome Trust

Fish May Provide Answers to Stopping Disease Spread, Wayne State University Researcher Says
Dec. 8, 2011 —Wayne State University

How Salmonella Forms Evil Twins to Evade the Body’s Defenses
Dec. 7, 2011—University of Washington

When Prophecy Fails: How to Better Predict Success in HIV Prevention Clinical Trials
Dec. 7, 2011—University of North Carolina at Chapel Hill

Novel Drug Wipes Out Deadliest Malaria Parasite Through Starvation
Dec. 7, 2011 —Albert Einstein College of Medicine

UCLA Researchers Suggest Unconventional Approach to control HIV Epidemics
Dec. 7, 2011—UCLA

Infectious Fungus, Thought to be Asexual, Isn’t
Dec. 5, 2011—Brown University

Defensive Measures: Toward a Vaccine for Ebola
Dec. 4, 2011 —Arizona State University

Cell Surface Mutation Protects Against Common Type of Malaria
Dec. 1, 2011—Case Western Reserve University School of Medicine

Vaccine Targeting Latent TB Enters Clinical Testing
Dec. 1, 2011—Statens Serum Institut

School Receives $8 Million Grant to Study Asthma, Allergies
Dec 1, 2011—Washington University School of Medicine in St. Louis

November 2011 

Biologists Deliver Neutralizing Antibodies that Protect Against HIV Infection in Mice
Nov. 30, 2011—Caltech

New Approach to Graft-versus-Host Disease Treatment Results in Sustained Improvement for Some Patients
Nov. 30, 2011—Dana-Farber Cancer Institute

Scientists Discover Anti-Inflammatory Polyphenols in Apple Peels
Nov. 30, 2011—Federation of American Societies for Experimental Biology

Scripps Florida Scientist Awarded $3.4 Million for HIV/AIDS Research
Nov. 30, 2011—Scripps Research Institute

Timing is Everything: Bacterial Attachment Mimics the Just-in-Time Industrial Delivery Model
Nov. 29, 2011—Indiana University Bloomington

SRI Researchers Validate Preclinical Effectiveness of Tuberculosis Drug Target that Could Shorten Treatment Time
Nov. 29, 2011—SRI

Stopping “Superbugs” in their Tracks
Nov. 18, 2011—University of Virginia Health System

UofL Researcher Determines How Legionnaires’ Bacteria Cause Disease; Science Publishes Results
Nov. 17, 2011—University of Louisville

Bacteria Responsible for Middle Ear Infections, Pink Eye and Sinusitis May Protect Themselves by Stealing Immune Molecules
Nov. 17, 2011—Nationwide Children's Hospital

Drug Clears Chronic Urinary Infections in Mice
Nov. 16, 2011—Washington University School of Medicine in St. Louis

New TB Treatment Limits Infection While Reducing Drug Resistance
Nov. 16, 2011—Emory University

Wayne State University Researchers Receive NIH Funding to Study Novel Treatment for Antibiotic-Resistant Bacteria
Nov. 16, 2011—Wayne State University

First Combination ARV Vaginal Ring for HIV Prevention Being Tested in Phase I Safety Trial
Nov. 15, 2011—Microbicide Trials Network

US Government HIV/AIDS Clinical Trial Sites to Accelerate Completion of Phase III TB Drug Trial
Nov. 15, 2011—GCI Health- TB Alliance

Contrasting Patterns of Malaria Drug Resistance Found Between Humans and Mosquitoes
Nov. 15, 2011—Johns Hopkins Bloomberg School of Public Health

Early Acyclovir for Eczema Herpeticum Shortens Hospital Stay
Nov. 14, 2011—Children's Hospital of Philadelphia

Bacterial Genes Tell the Tale of an Outbreak’s Evolution
Nov. 14, 2011—Harvard Medical School and Children’s Hospital Boston

Malaria's Achilles' Heel Revealed?
Nov. 9, 2011—Wellcome Trust Sanger Institute

Global Flu Watch: Report of Rare Flu Coinfection in Southeast Asia Hot Spot
Nov. 2, 2011—American Society of Tropical Medicine and Hygiene

Mayo Clinic Researchers Discover Why Measles Spreads so Quickly
Nov. 2, 2011—Mayo Clinic

‘Protein Microarrays’ May Reveal New Weapons Against Malaria
Nov. 1, 2011—Walter and Eliza Hall Institute

Acinetobacter baumannii Found Growing in Nearly Half of Infected Patient Rooms
Nov. 1, 2011—University of Maryland School of Medicine

Team Discovers How a Cancer-Causing Bacterium Spurs Cell Death
Nov. 1, 2011—University of Illinois at Urbana-Champaign

Aeolus Pharmaceuticals Announces Positive Results From Study of AEOL 10150 and Neupogen® as Combination Therapy for Treatment of Acute Radiation Syndrome
Nov. 1, 2011—Aeolus Pharmaceuticals

October 2011

PharmAthene Progresses Second Generation rPA Anthrax Vaccine
Oct. 31, 2011—PharmAthene

Enzymes Act Like a Switch, Turning Antibiotic Resistance On and Off in Enterococci
Oct. 31, 2011—Medical College of Wisconsin

Study Finds Specific Gene Linked to Cold Sore Susceptibility
Oct. 28, 2011—Infectious Diseases Society of America

NYU College of Nursing Receives $2.8M NIH/NIAID Grant to Study Combination HIV Prevention for Kenyan Youth
Oct. 28, 2011—NYU College of Nursing

Natural Killer Cells Could be Key to Anthrax Defense
Oct. 27, 2011—University of Texas Medical Branch at Galveston

Building Better HIV Antibodies
Oct. 27, 2011—Caltech

What Role do Cytokines Play in Autoimmune Diseases?
Oct. 27, 2011—Department of Microbiology and Immunology, University of Maryland School of Medicine

Veterinary Researchers Discover First U.S. Strains of Hepatitis E Virus from Rabbits
Oct. 26, 2011—Virginia Tech

Standard Definition of Loss-to-Follow-up for ART patients
Oct. 25, 2011—University of Alabama, Birmingham

Obesity Limits Effectiveness of Flu Vaccines
Oct. 25, 2011—UNC Gillings School of Global Public Health

Study Offers Clues as to Why Some Patients Get Infections from Cardiac Implants
Oct. 24, 2011—Ohio State

Genetic Difference in Staph Infects Some Heart Devices, Not Others
Oct. 24, 2011—Duke University Medical Center

Geoscientists Find Key to Why Some Patients Get Infections from Cardiac Implants
Oct. 24, 2011—National Science Foundation

USF Study Suggests Dormant Malaria Parasites in Red Blood Cells May Contribute to Treatment Failure
Oct. 24, 2011—University of South Florida

Unravelling the Mysteries of the Natural Killer Within Us
Oct. 24, 2011—Monash University

Human Norovirus In Groundwater Remains Infective After Two Months
Oct. 20, 2011—Emory University

BU Uncovers Mechanisms Used by Wolbachia Bacteria to Control Vectors of Deadly Diseases
Oct. 20, 2011—Boston University Medical Center

West Nile Virus Transmission Linked to Land Use Patterns, 'Super-Spreaders'
Oct. 20, 2011—University of California Santa Cruz

COPD Foundation Announces Landmark Measure: 1,000th Patient Enrolled in Bronchiectasis Research Registry
Oct. 20, 2011—COPD Foundation

Research Could Lead to New Treatments for IBD, Viral Infections
Oct. 19, 2011—University of Texas Southwestern Medical Center

T32 Interdisciplinary NIH Training Grant Awarded
Oct. 19, 2011—Boston University Medical Center

Early HIV Treatment Dramatically Increases Survival in Patients Co-Infected with Tuberculosis 
Oct. 19, 2011—Children's Hospital Boston

Scientists Report Major Advance in Human Antibody Therapy Against Deadly Hendra Virus
Oct. 19, 2011—Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.

Scientists Report Major Advance in the Treatment of Hendra Virus 
Oct. 20, 2011—Boston University

SAIC Awarded Contract by National Institute of Allergy and Infectious Diseases
Oct. 19, 2011—SAIC

NIAID Awards Contract Worth up to $36 Million for the Development of a Novel Tetraphase
Antibiotic
Oct. 19, 2011—Tetraphase Pharmaceuticals, Inc.

Trudeau Institute Announces its Latest Discovery in the Fight Against Tuberculosis
Oct. 18, 2011—Trudeau Institute

Trudeau Institute Reports New Approach to Treating Listeria Infections; Strategy Could Lead to New Treatments for Sepsis
Oct. 17, 2011—Trudeau Institute

Hospital Superbug Debugged
Oct. 14, 2011—Monash University School of Biomedical Sciences

Study Could Help Battle Against Superbugs
Oct. 14, 2011—The Roslin Institute and Centre for Infectious Diseases, University of Edinburgh

Scripps Research Scientists Reveal Surprising Picture of How Powerful Antibody Neutralizes HIV
Oct. 13, 2011—Scripps Research Institute

Enanta Awarded up to $42.7 Million NIAID Contract to Develop a Novel Broad Spectrum Bicyclolide Antibiotic
Oct. 13, 2011—Enanta Pharmaceuticals, Inc.

Scientists Find Vitamin D is Crucial in Human Immune Response to Tuberculosis
Oct. 12, 2011—University of California - Los Angeles Health Sciences

CUBRC Awarded NIAID Contract Worth up to $36 Million for the Development of a Novel Tetracycline-Based Antibiotic
Oct. 11, 2011—CUBRC

Peanut Allergy Turned Off by Tricking Immune System
Oct. 11, 2011—Northwestern University’s Feinberg School of Medicine

Study Could Help Improve Gene Therapy for Heart Disease, Cancer
Oct. 11, 2011—Loyola University Health System

United Therapeutics Subsidiary Enters Into Contract With National Institutes of Health for Award of up to $45 Million to Support Glycobiology Antiviral Program
Oct. 10, 2011—Unither Virology

Induced Immune Tolerance for Kidney Transplantation
Oct. 5, 2011—Stanford University School of Medicine

Center for Modeling Immunity to Enteric Pathogens Releases Revolutionary Software
Oct. 5, 2011—Virginia Tech –Virginia Bioinformatics Institute

Long-Term Oral Meds Cause Better Outcomes in Babies with HSV
Oct. 5, 2011—University of Alabama at Birmingham

Researchers Question National Quality Measure for Childhood Asthma
Oct. 4, 2011—University of Colorado Denver

Estimating Severity of a Flu Epidemic
Oct. 4, 2011

Researchers from Boston University Receive Grant to Develop Improved Virus Detection System
Oct. 4, 2011—Boston University Medical Center

Scientists Find Mechanism that Leads to Drug Resistance in Bacteria Causing Melioidosis
Oct.4, 2011

Nanoparticles Seek and Destroy Glioblastoma in Mice
Oct. 3, 2011—Sanford-Burnham Medical Research Institute

GeoVax Phase 2a Clinical Trial Completes Enrollment
Oct. 3, 2011—GeoVax

Tuberculosis Bacterium's Outer Cell Wall Disarms the Body's Defense to Remain Infectious
Oct. 3, 2011—Ohio State University

Rebooting the System: Immune Cells Repair Damaged Lung Tissues after Flu Infection, Penn Study Finds
Oct. 3, 2011—University of Pennsylvania School of Medicine

Study in Lancet Finds Use of Hormonal Contraception Doubles HIV Risk
Oct. 3, 2011—University of Washington

September 2011

G-Zero Therapeutics Receives $3M in NIH Advanced Technology Small Business Innovation Research Funding
Sept. 30, 2011—G-Zero Therapeutics

Hunting for “Hot Spots” for Chromosome Reshuffling
Sept. 29, 2011—Children's Hospital Boston

Tracing an Elusive Killer Parasite in Peru
Sept. 27, 2011—University of Pennsylvania School of Medicine

Enzymes Possible Targets for New Anti-Malaria Drugs
Sept. 27, 2011—Virginia Tech

New Study Adds Further Guidance on When to Start Antiretroviral Therapy for HIV 
Sept. 26, 2011—University of North Carolina at Chapel Hill

Compound Kills Highly Contagious Flu Strain by Activating Antiviral Protein
Sept. 26, 2011—UT Southwestern Medical Center

Targeting HIV's Sugar Coating
Sept. 23, 2011—University of Utah

Newly Identified Antibodies may Improve Pneumonia Vaccine Design
Sept. 22, 2011—Albert Einstein College of Medicine

Decoding Vaccination: Mayo Researchers Reveal Genetic Underpinnings of Response to Measles Vaccine
Sept. 22, 2011—Mayo Clinic

Researchers Discover How "Promiscuous Parasites" Hijack Host Immune Cells
Sept. 21, 2011—Cornell University

Cost-Effectiveness of Early Versus Standard Antiretroviral Therapy in HIV-Infected Adults in Haiti
Sept. 20, 2011—PLoS Medicine

"Natural Experiment" Documents the Population Benefit of Vaccinating Preschoolers Against the Flu
Sept. 19, 2011—Children's Hospital Boston

Expanding Flu Vaccinations to Older Children Reduces Emergency Visits for Flu-Like Illnesses by 34 Percent
Sept. 19, 2011—Canadian Medical Association

Researchers Identify Components that Keep Immune System in Check
Sept. 19, 2011—University of North Carolina at Chapel Hill

Shark Compound Proves Potential as Drug to Treat Human Viruses, says GUMC Researcher
Sept. 19, 2011—Georgetown University Medical Center

Mast Cells Reduce Toxicity of Gila Monster and Scorpion Venom
Sept. 19, 2011—Stanford University School of Medicine

2009 H1N1 Pandemic Flu More Damaging to Lungs, Opens Opportunities for Bacterial Infection
Sept. 19, 2011—American Society for Microbiology

Breast Milk Antibody Fights HIV but Needs Boost
Sept. 19, 2011—American Society For Microbiology

Danger Signal Limits Hepatitis C Infection
Sept. 19, 2011—American Society For Microbiology

Elite Controllers Block Integration of HIV DNA into Host Genome
Sept. 19, 2011—American Society For Microbiology

Scripps Research Team Discovers Treatable Mechanism Responsible for Often Deadly Response to Flu
Sept.15, 2011—The Scripps Research Institute

Notre Dame Researchers Demonstrate Antibiotic Sensing Event Central to MRSA Antibiotic Resistance
Sept. 15, 2011—University of Notre Dame

Advanced BioScience Laboratories Awarded “NIAID Preclinical Development Support”
Sept. 14, 2011—Advanced BioScience Laboratories

Mass. Eye and Ear Awarded Largest NIH Grant in Hospital’s History: $11 Million/5-year Project to Coordinate Harvard-wide Project on Antibiotic Resistance
Sept. 6, 2011—Massachusetts Eye and Ear Infirmary

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