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News from NIAID-Supported Institutions for 2014

Below are links to press releases about NIAID-funded research from some of the institutions we support.

December 2014

Molecules Seen Binding to HIV-1’s Protective Capsule, Blocking Infection
December 30, 2014—The University of Texas Health Science Center at San Antonio

New Treatment Strategy Allows Lower Doses of Toxic Tuberculosis Drug Without Compromising Potency
December 30, 2014—Johns Hopkins University School of Medicine

Artful Imaging Leads to FASEB Honor
December 30, 2014—Albert Einstein College of Medicine

Lyme Disease Enhances Spread of Emerging Tick Infection
December 29, 2014—Yale School of Public Health

Tracing Evolution of Chicken Flu Virus Yields Insight Into Origins of Deadly H7N9 Strain
December 29, 2014— St. Jude Children’s Research Hospital

The Protein GRP78 Identified as a Possible Universal Therapeutic Target for Multiple Viral and Bacterial Infections, Including Ebola, Influenza and Hepatitis and Brain Cancer
December 29, 2014—Virginia Commonwealth University

Enzyme's Alter Ego Helps Activate the Immune System
December 29, 2014—The Johns Hopkins University

Miller School Researchers Receive $5.67 Million Grant for HIV/AIDS Clinical Trials 
December 29, 2014—University of Miami Miller School of Medicine

Team Finds Mechanism of Toxin’s Inflammatory Effect on Lungs   
December 29, 2014—The University of Texas Health Science Center at San Antonio

Hearing Loss and HIV 
December 26, 2014—San Diego State University

Penn and UGA Awarded $23.4 Million Contract for Pathogen Genomics Database   
December 18, 2014—University of Pennsylvania

Study Identifies 53 Approved Drugs that May Block Ebola Infection 
December 17, 2014—Icahn School of Medicine at Mount Sinai

Penn Researchers Tame the Inflammatory Response in Kidney Dialysis   
December 11, 2014—Perelman School of Medicine at the University of  Pennsylvania

Cause of Malaria Drug Resistance in SE Asia Identified 
December 11, 2014—Columbia University Medical Center

New Notre Dame-IUSM Study Examines Important Ebola Protein 
December 10, 2014—University of Notre Dame

Novel fMRI Technique Identifies HIV-Associated Cognitive Decline Before Symptoms Occur 
December 10, 2014—Georgetown University Medical Center

Drug Developed at Pitt Proves Effective Against Antibiotic-Resistant ‘Superbugs’   
December 10, 2014—University of Pittsburgh Center for Vaccine Research

Immunizing Schoolkids Fights Flu in Others, Too 
December 9, 2014—University of Florida
Vaccine Holds Hope of Preventing Antibiotic Resistant Skin Infections 
December 8, 2014—Los Angeles Biomedical Research Institute

Rapid Ebola Test Is Focus of NIH Grant to Rutgers Scientist 
December 8, 2014—Rutgers New Jersey Medical School

November 2014

Notre Dame Biologist Nora Besansky leads International Consortium in Sequencing the Genomes of Malaria-Carrying Mosquitoes 
November 27, 2014—University of Notre Dame

Drugs to Block Angiogenesis Could Provide New Treatment for TB 
November 24, 2014—Duke University School of Medicine
Team Reveals Weak Spots in Ebola’s Defenses 
November 24, 2014—The Scripps Research Institute

Researchers Tease Out Glitches in Immune System's Self-Recognition 
November 21, 2014—The Johns Hopkins University

Halting the Hijacker: Cellular Targets to Thwart Influenza Virus Infection 
November 20, 2014—University of Wisconsin-Madison

Breakthrough in Managing Yellow Fever Disease 
November 20, 2014—University of California, Riverside

New Study Reveals Why Some People May Be Immune to HIV-1   
November 19, 2014—University of Minnesota
UTHealth Awarded $7.3 Million for Health Information Technology Research 
November 18, 2014—The University of Texas Health Science Center at Houston

Creating Trust in the Time of Ebola 
November 17, 2014—Johns Hopkins Bloomberg School of Public Health

Ferret Genome Holds Clues to Respiratory Diseases 
November 17, 2014—University of Washington
Semen Directly Impairs Effectiveness of Microbicides that Target HIV   
November 12, 2014—Gladstone Institutes 
Research Suggests How Mosquitoes Evolved an Attraction to Human Scent 
November 12, 2014—The Rockefeller University

Inhaled Ebola Vaccine May Offer Long-Term Protection from Virus 
November 3, 2014—The University of Texas at Austin

New Technique Efficiently Turns Antibodies Into Highly Tuned “Nanobodies” 
November 2, 2014—Rockefeller University


October 2014

Improved Mouse Model Will Accelerate Research on Potential Ebola Vaccines, Treatments 
October 31, 2014—University of North Carolina at Chapel Hill
Study: “Wimpy” Antibody Protects Against Kidney Disease in Mice 
October 31, 2014—University of Cincinnati

Mouse Model Suggests Varied Genetic Dispositions to Ebola 
October 30, 2014—University of Washington
UC Davis Scientists Discover Exact Receptor for DEET That Repels Mosquitoes 
October 27, 2014—University of California, Davis

Divide and Conquer: Novel Trick Helps Rare Pathogen Infect Healthy People   
October 17, 2014—University of Birmingham

Scientific Breakthrough Will Help Design the Antibiotics of the Future   
October 17, 2014—University of Bristol

Study Models Ways to Cut Mexico’s HIV Rates 
October 15, 2014—Brown University

Antiretroviral Therapy Benefits HIV-infected Stimulant Users, UCSF Study Shows 
October 10, 2014—University of California - San Francisco

School of Medicine Begins Ebola Vaccine Trials 
October 9, 2014—University of Maryland School of Medicine (UM SOM)

UAB Part of NIH-Funded Research Consortia Studying More Than 200 Rare Diseases   
October 9, 2014—University of Alabama at Birmingham

Scientists Discover Pain Receptor on T-Cells 
October 5, 2014—University of California, San Diego School of Medicine

Gut Bacteria Are Protected by Host During Illness 
October 2, 2014—University of Chicago

September 2014

Surprising Diversity of Antibody Family Provides Clues for HIV Vaccine Design 
September 29, 2014—The Scripps Research Institute

Geisel Researchers Contribute to Study of Trained Immunity 
September 26, 2014—Geisel School of Medicine at Dartmouth
Dry Roasting Could Help Trigger Peanut Allergy 
September 22, 2014—Oxford University

Penn Researchers Describe New Cancer Drug Target Involving Lipid Chemical Messengers 
September 19, 2014—Perelman School of Medicine, University of Pennsylvania

Research Predicts Possible 6,800 New Ebola Cases This Month 
September 19, 2014—Arizona State University

Research Yields a Game Changer for Improving Understanding of Ebola and Great Apes 
September 18, 2014—The Wildlife Conservation Society

Professor Dennis Burton: In Search of an Effective HIV/AIDS Vaccine 
September 15, 2014—The Scripps Research Institute
New Insights in Survival Strategies of Bacteria   
September 14, 2014—VIB (the Flanders Institute for Biotechnology)
Geneva & Partners in Development of Ebola Drug 
September 12, 2014—The Geneva Foundation
Study Sheds Light on Asthma and Respiratory Viruses   
September 9, 2014—Washington University School of Medicine in St. Louis
Unusual Immune Cell Needed to Prevent Oral Thrush, Pitt Researchers Find 
September 8, 2014—University of Pittsburgh School of Medicine
Suppressing Food Allergies Quickly Is the Goal of UC Research Team 
September 8, 2014—University of Cincinnati College of Medicine
Team Identifies Important Regulators of Immune Cell Response   
September 8, 2014—The Scripps Research Institute
MCW Scientists to Investigate New Therapy for Obstructive Lung Disease 
September 4, 2014—The Medical College of Wisconsin

Avian Influenza Virus Isolated in Harbor Seals Poses a Threat to Humans 
September 4, 2014—St. Jude Children’s Research Hospital
Leaky Gut—A Source of Non-AIDS Complications in HIV-Positive Patients 
September 3, 2014—Case Western Reserve University School of Medicine

War Between Bacteria and Phages Benefits Humans   
September 2, 2014—Tufts University

August 2014

Discovery Reveals how Bacteria Distinguish Harmful Versus Helpful Viruses 
August 31, 2014—The Rockefeller University

Drug Shows Promise Against Sudan Strain of Ebola in Mice 
August 28, 2014—Albert Einstein College of Medicine

Synthesis Produces New Antibiotic 
August 28, 2014—Rice University

Key to Universal Flu Vaccine: Embrace the Unfamiliar 
August 27, 2014—Emory Vaccine Center
Fungus Deadly to AIDS Patients Found to Grow on Trees 
August 21, 2014—Duke University School of Medicine

Some Anti-Inflammatory Drugs Affect More Than Their Targets
August 21, 2014—Johns Hopkins University School of Medicine

Food Allergies More Widespread Among Inner-City Children 
August 14, 2014—Johns Hopkins Medicine

Gut Flora Influences HIV Immune Response 
August 13, 2014—Duke Medicine

OMRF Receives $14.5 Million Grant to Continue Anthrax Studies 
August 13, 2014—Oklahoma Medical Research Foundation

Developing A Better Test For Lyme Disease Diagnosis 
August 6, 2014—RareCyte, Inc.

July 2014

Molecule Enhances Copper’s Lethal Punch Against Microbes 
July 31, 2014—Duke University

Researchers Uncover Clues to Flu’s Mechanisms 
July 31, 2014—Rice University
"Viral Fitness" Discovery Defines HIV Vulnerability 
July 11, 2014—Emory University Health Sciences
Recalled Yogurt Contained Highly Pathogenic Mold 
July 8, 2014—Duke University
NYU Researchers Tackle Racial/Ethnic Disparities in HIV Medical Studies   
July 7, 2014—New York University College of Nursing
Researchers Learn How Beryllium Causes Deadly Lung Disease 
July 3, 2014—National Jewish Health
Screening Children for Celiac Disease 
July 3 2014—University of Colorado School of Medicine

Institute for Genome Sciences Awarded NIAID Grant 
July 1, 2014—University of Maryland School of Medicine

Sorrento Awarded up to $2.6 Million from the National Institutes of Health (NIH) for the Development of New Anti-bacterial Bispecific Antibodies and Antibody Formulated Drug Conjugates 
July 1, 2014—Sorrento Therapeutics, Inc.

June 2014

Fighting Parasitic Infection Inadvertently Unleashes Dormant Virus 
June 26, 2014—Washington University School of Medicine in St. Louis

New Infections Cause Dormant Viruses to Reactivate 
June 26, 2014—University of Florida
Researchers One Step Closer to Countering Deadly Nipah Virus 
June 25, 2014—University of Texas Medical Branch at Galveston

Lowering Toxicity of New HIV Drugs Predicted to Improve Life Expectancy 
June 25, 2014—University of Pittsburgh Graduate School of Public Health

TSRL Announces Receipt of $4.2 Million in New SBIR Funding 
June 24, 2014—Therapeutic Systems Research Laboratories, Inc.

New Monkey Model for AIDS Offers Promise for Medical Research 
June 19, 2014—The Rockefeller University


New Stanford Blood Test Identifies Heart-Transplant Rejection Earlier Than Biopsy Can 
June 18, 2014—Stanford University

Researchers Map Gene Differences in Yellow Fever, Malaria Mosquitoes, to Help Prevent Disease 
June 17, 2014—Virginia Tech

Study Shows Chikungunya Virus Mutation Places Several Countries at Risk of Epidemic Circulation 
June 16, 2014—University of Texas Medical Branch at Galveston

Genetic Barcode for Malaria Could Help Contain Outbreaks 
June 13, 2014—London School of Hygiene & Tropical Medicine

Grant to Entomologist Will Advance Research on African Malaria Mosquito 
June 12, 2014—University of California, Riverside
Dormant Viruses Re-Emerge in Patients with Lingering Sepsis, Signaling Immune Suppression   
June 11, 2014—Washington University School of Medicine in St. Louis

Study Finds How Protein Blocks HIV Life Cycle in Elite Controllers   
June 11, 2014—Massachusetts General Hospital (MGH)

TB Dogma Upended: Even Uninfected Cells Trigger Immune Defenses 
June 11, 2014—NYU Langone Medical Center

Genes Found in Nature Yield 1918-Like Virus with Pandemic Potential 
June 11, 2014—University of Wisconsin-Madison

A Key Step Toward a Safer Strep Vaccine 
June 11, 2014—University of California, San Diego School of Medicine

Infant Immune Systems Learn Fast, but Have Short Memories 
June 11, 2014—Cornell University

Herpes Infected Humans Before They Were Human 
June 10, 2014—University of California, San Diego School of Medicine
Finding Could Lead to New Strategies for Malaria Control 
June 6, 2014—Harvard School of Public Health

HIV Transmission Networks Mapped to Reduce Infection Rate 
June 5, 2014—University of California, San Diego School of Medicine

Researchers at the Gladstone Institutes Find Novel Approach to Reactivate Latent HIV   
June 5, 2014—Gladstone Institutes


May 2014

Penn Medicine Program Receives $10 Million Renewal for Studying the Oldest Branch of the Immune System 
May 29, 2014—University of Pennsylvania Perelman School of Medicine

UNL Team Awarded $1.9M to Develop New Approach to HIV Vaccine 
May 29, 2014—University of Nebraska-Lincoln
Stanford Researchers Discover Immune System's Rules of Engagement 
May 22, 2014—Stanford School of Medicine

Bacterial Adaptation Contributes to Pneumococcal Threat in Sickle Cell Disease Patients 
May 22, 2014—St. Jude Children’s Research Hospital

Scientists Develop New Approach for Sampling Gut Bacteria 
May 19, 2014—The Forsyth Institute
Painkillers May Decrease Susceptibility to Recurring Urinary Infections   
May 18, 2014—Washington University School of Medicine
Breakthrough in HIV/AIDS Research Gives Hope for Improved Drug Therapy 
May 16, 2014—University of Pittsburgh Center for Vaccine Research
"Bystander" Chronic Infections Thwart Development of Immune Cell Memory, Penn Study Finds 
May 15, 2014—University of Pennsylvania Perelman School of Medicine
Penn Vet Study Reveals Salmonella’s Hideout Strategy 
May 15, 2014— University of Pennsylvania School of Veterinary Medicine

TB Lung Infection Causes Changes in the Diversity of Gut Bacteria in Mice 
May 13, 2014—Johns Hopkins

Birth by C-Section, Early Antibiotic Use Put Kids at Risk for Allergic Esophagitis   
May 12, 2014—Johns Hopkins Children’s Center

Carbohydrates Direct Immunity Against Camouflaged Bacteria 
May 12, 2014—Emory University School of Medicine
$32 Million NIH Grant Funds Study of Multipurpose Infection Fighter   
May 8, 2014—Washington University School of Medicine
UTMB Awarded $4.4M to Develop Universal Flu Vaccine   
May 7, 2014—University of Texas Medical Branch
Immune Cells Outsmart Bacterial Infection by Dying, Penn Vet Study Shows 
May 5, 2014—University of Pennsylvania School of Veterinary Medicine

Penn Vet Research Identifies Compounds That Control Hemorrhagic Viruses 
May 1, 2014—University of Pennsylvania School of Veterinary Medicine

April 2014

Autoimmune Diseases May Succumb to New Drug Strategy 
April 30, 2014—UC San Francisco

New Experimental Vaccine Produces Immune Response Against Middle East Respiratory Syndrome Coronavirus (MERS-CoV) 
April 30, 2014—University of Maryland School of Medicine

Live Virus Implicates Camels in MERS Outbreak 
April 29, 2014—Columbia University Mailman School of Public Health

Low Cholesterol in Immune Cells Tied to Slow Progression of HIV 
April 29, 2014—University of Pittsburgh Graduate School of Public Health
Team Finds New Point of Attack on HIV for Vaccine Development 
April 28, 2014—The Scripps Research Institute
Multitarget TB Drug Could Treat Other Diseases, Evade Resistance 
April, 17, 2014—University of Illinois
Deadly Human Pathogen Cryptococcus Fully Sequenced 
April 17, 2014—Duke University
HIV+ Women Respond Well to HPV Vaccine 
April 16, 2014— Brown University
Scientists Unlock Secrets of Protein Produced by Disease-Causing Fungus   
April 16, 2014—The University of Texas Health Science Center at San Antonio 
New MRSA Superbug Emerges in Brazil 
April 16, 2014—The University of Texas Health Science Center at Houston   
Some Immune Cells Defend Only One Organ 
April 16, 2014—Washington University School of Medicine in St. Louis   
HIV Battle Must Focus on Hard-Hit Streets
April 10, 2014—Brown University
Researchers Discover Possible New Target to Attack Flu Virus 
April 9, 2014—The University of Texas at Austin
Rapid, Broad Countermeasures Sought Against Mystery Infections 
April 8, 2014—University of Washington
Disruption of VISTA Plays an Important Role in Regulating Immune Response 
April 7, 2014—Geisel School of Medicine at Dartmouth

Scientists Generate 3D Structure for the Malaria Parasite Genome
April 4, 2014—University of California, Riverside


March 2014

Air Pollution from Traffic Increases Odds of Hospital Readmission for Asthma 
March 27, 2014—Cincinnati Children’s Hospital Medical Center
Using Tobacco to Thwart West Nile Virus 
March 27, 2014—Arizona State University
Penn Dental Medicine-NIH Team Reverses Bone Loss in Immune Disorder 
March 26, 2014—University of Pennsylvania School of Dental Medicine
New Childhood Tuberculosis Estimates Double the Number Previously Thought   
March 24, 2014—Brigham and Women's Hospital
Drugs Fail to Reawaken Dormant HIV Infection 
March 24, 2014—Johns Hopkins Medicine
Consortium Wins Up to $28 Million to Find Best Ebola Treatment 
March 20, 2014—The Scripps Research Institute
Nasty Nanoinjectors Pose a New Target for Antibiotic Research   
March 13, 2014—University of Kansas
Notre Dame Chemists Discover New Class of Antibiotics 
March 6, 2014—University of Notre Dame
In First Moments of Infection, a Division and a Decision 
March 4, 2014—University of California, San Diego School of Medicine
Novel Drug Treatment Protects Primates from Deadly Marburg Virus 
March 3, 2014—U.S. Army Medical Research Institute of Infectious Diseases

BioCryst Announces Nature Publication Demonstrating Efficacy of BCX4430 in a Non-Human Primate Model of Filovirus Infection
March 3, 2014—BioCryst Pharmaceuticals, Inc.

February 2014

Mayo Clinic Discovers African-Americans Respond Better to Rubella Vaccine 
February 26, 2014—Mayo Clinic 
UNC Researchers Discover New Target for Dengue Virus Vaccine   
February 26, 2014—University of North Carolina 
Vitamin A May Help Boost Immune System to Fight Tuberculosis 
February 25, 2014—UCLA
Taming Microbes to Combat Antibiotic Resistance NIH Grant to LA BioMed Researchers Funds New Approach to Treat MRSA 
February 25, 2014—Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
Northwestern Medicine Awarded More Than $8.4 Million for Chronic Rhinosinusitis Research 
February 25, 2014—Northwestern Memorial Hospital

Essential Protein Discovered for Malaria Parasite's Transmission to Mosquitos
February 20, 2014—Penn State

The Nose Knows in Asthma 
February 19, 2014—National Jewish Health

Of Mice and Men: Fine-Tuning Salmonella-Based Vaccines 
February 17, 2014—Arizona State University

Environment Influences Ability of Bacterium to Block Malaria Transmission 
February 17, 2014—Penn State

Researchers Find Source of New Lineage of Immune Cells 
February 14, 2014—University of Chicago

UA Study on Flu Evolution May Change Textbooks, History Books 
February 14, 2014—University of Arizona

Popular Disinfectants Do Not Kill HPV
February 12, 2014—Penn State

Field Trials Show New Technology Able To Prevent Lyme Disease Transmission 
February 12, 2014—US BIOLOGIC

Chips that Listen to Bacteria
February 11, 2014—Columbia University School of Engineering and Applied Science

Researchers Discover Immune Signature that Predicts Poor Outcome in Influenza Patients 
February 10, 2014—St. Jude Children’s Research Hospital

Newly Found Tactics in Offense-Defense Struggle with Hepatitis C Virus 
February 10, 2014—University of Washington

Caltech-Developed Method for Delivering HIV-Fighting Antibodies Proven Even More Promising 
February 9, 2014—California Institute of Technology

New Investigational Drug Holds Promise for Combatting Deadly Mucormycosis Infections   
February 6, 2014—Los Angeles Biomedical Research Institute
UC Irvine Salmonella Study has Surprising Results 
February 6, 2014—University of California, Irvine
Quick Test Finds Signs of Diarrheal Disease 
February 6, 2014—Rice University
Powerful Bacterial Immune Response Defined by New Study   
February 6, 2014—University of California, Davis
The Ultimate Decoy: Scripps Research Institute Scientists Find Protein that Helps Bacteria Misdirect Immune System
February 6, 2014—The Scripps Research Institute
Decoding Dengue and West Nile
February 6, 2014—University of Michigan
Immune Cells Need a Second Opinion   
February 4, 2014—University of Bonn Medical Center
Bacterial Fibers Critical to Human, Avian Infection 
February 4, 2014—Biodesign Institute at Arizona Sta
te Unive
HIV-Infected Teens Delaying Treatment Until Advanced Disease, Johns Hopkins Study Shows 
February 3, 2014—Johns Hopkins
Mosquito Sperm Have a Sense of Smell
February 3, 2014—Vanderbilt University

January 2014

DNA of Peanut-Allergic Kids Changes with Immune Therapy, Study Finds 
January 31, 2014—Stanford University School of Medicine

U.Va., Russian Researchers Target Drug-Resistant TB 
January 31, 2014—University of Virginia School of Medicine

A Detailed Look at HIV in Action 
January 30, 2014—California Institute of Technology

Trick that Aids Viral Infection is Identified 
January 30, 2014—Washington University School of Medicine in St. Louis

Findings Point to Potential Treatment for virus Causing Childhood Illnesses 
January 29, 2014—Purdue University

Promising Class of Antibiotics Discovered for Treatment of Drug-Resistant Tuberculosis 
January 27, 2014—St. Jude Children’s Research Hospital

Team to Study Control of Malaria-Related Parasite Growth with $2.1 Million NIH Grant 
January 22, 2014—University of South Florida

Decoded: DNA of Blood-Sucking Worm that Infects World’s Poor
January 19, 2014—Washington University School of Medicine in St. Louis

Soligenix Announces Positive One-Year High-Temperature Stability Results with ThermoVax™ Vaccine Heat Stabilization Technology 
January 15, 2014—Soligenix, Inc.

Engineering Professor Co-Authors Nature Medicine Paper on HIV 
January 13, 2014—University of Delaware

Wistar to Launch Largest Randomized Trial Aiming for an HIV Cure by Diminishing Viral Reservoir Beyond Current Therapies 
January 13, 2014— The Wistar Institute

Enanta Pharmaceuticals Initiates Phase 1 Study of MRSA Infection Candidate EDP-788
January 13, 2014—Enanta Pharmaceuticals, Inc.

MGH/Ragon Institute Study Identifies Population of Stem-Like Cells Where HIV Persists in Spite of Treatment
January 13, 2014—Massachusetts General Hospital

Knopp Biosciences And NIH to Collaborate in Evaluating Dexpramipexole in Patients with Hypereosinophilic Syndrome
January 8, 2014—Knopp Biosciences LLC

Scripps Florida Scientists Identify Possible Key to Drug Resistance in Crohn’s Disease
January 8, 2014—The Scripps Research Institute

On-Demand Vaccines Possible with Engineered Nanoparticles
January 7, 2014—University of Washington

Finding About Classic Suppressor of Immunity Points Toward New Therapies for Bad Infections
January 7, 2014—Georgia Regents University

Draper Nanotechnology Could Fight Influenza, Other Viruses
January 6, 2014—Draper Laboratory


Last Updated May 11, 2015