For Institute program-specific acronyms, go to NIAID Profile and Fact Book.
Applicant who is within 10 years of either of the following:
ESI is a subset of new investigator status, so ESIs must meet those criteria as well. ESI status affects initial peer review and institute funding decisions.
Go to these resources:
Congressional requirement that a federal agency set aside funds within an appropriation for a stated recipient or purpose, for example, to establish a research center grant program or conduct a clinical trial.
NIH database system downloaded from IMPAC that shows the following information about a grant application:
ECB also lets members of NIAID's main advisory Council recommend awards early for fundable applications with no special concerns. See human subjects concern, human subjects codes, and animals in research codes.
Go to ECB and NIAID's Electronic Council Book SOP.
Information technology infrastructure that enables NIH and other federal agencies to electronically receive and review applications and administer grants. eRA enables NIH and its grantees to have an online dialogue throughout the life cycle of a grant. See eRA Commons.
Go to eRA.
Formerly used term. See Research Performance Progress Report (RPPR).
Formerly used term. See Research Portfolio Online Reporting Tool (RePORT).
Invention report due to NIAID within two months after an investigator gives written disclosure to an organizational official.
For more information on grants, go to NIAID's Invention Reporting Has Four Parts in the Strategy for NIH Funding and NIH's iEdison.
For more information on contracts, go to NIAID's Invention Reporting for Contracts SOP.
Concurrence by a full advisory Council or a subset of Council members (or occasionally another group) with an initial peer review group to recommend awards for funding. See second-level review.
Go to NIAID's Advisory Council portal.
For electronic applications, see Research and Related Budget component form.
For paper applications, Form page 5 in the PHS 398 Grant Application used when requesting more than $250,000 or applying from a foreign institution. Also see Detailed Budget for Initial Budget Period.
For smaller budgets, see modular budget.
Go to these resources:
Web-based interface where NIH grantees, staff, and the public access and share administrative information about grants. Part of Electronic Research Administration, it includes both restricted and public sites.
Go to eRA Commons.
For electronic grant applications, failure point resulting from validations in Grants.gov or the NIH eRA Commons. An error stops an application from becoming final and moving to the NIH Center for Scientific Review.
Errors reflect inaccuracies, inconsistencies, omissions, or incorrect formatting. See warning.
Go to these NIAID resources:
Percentage of increase applicants can request in a competing non-modular grant application to cover annual changes in the price of items and services. It covers personnel costs but not equipment. Also referred to as inflationary factor.
The awarded escalation factor is linked to the Biomedical Research and Development Price Index. See financial management plan and recommended level of future support.
Go to NIAID's Financial Management Plan on Paylines and Funding.
See early-stage investigator.
Standards in contracting used to evaluate an offeror's technical and operational effectiveness.
Go to NIAID's Technical Review SOPs on the Contracts portal.
NIAID management committee comprising staff from the NIAID Office of the Director, division directors, and other managers.
Executive Committee makes scientific and management policy decisions, allocates resources, establishes grant paylines, approves grant funding plans, and reviews concepts for presentation to NIAID's main advisory Council.
Human subjects term indicating six research categories exempt from human subjects regulations. See exemption for human subjects research.
Go to definitions in 45 CFR 46.101 and the NIAID Human Subjects Application and Grant Handbook.
Research excluded from human subjects regulations 45 CFR 46.101. The six human subjects exemptions rarely apply to NIAID-supported investigators because their research is either human subjects or not human subjects. See exemption categories for human subjects research.
FDA term for the exemption from the legal requirement that a drug be the subject of an approved marketing application before it is transported or distributed across state lines. The exemption takes place through an investigational new drug from the FDA.
Go to IND definition in 21 CFR 312.3 and FDA's Investigational New Drug (IND) Application.
Specimen or data that are no longer being collected.
Legislation providing greater autonomy to grantees based on regulation 45 CFR Part 74. With the exception of automatic carryover of funds from one budget period to the next, expanded authorities apply to all grants.
Go to these NIAID resources:
FDA process that gives access to investigational drugs and investigational medical devices, including treatment investigational new drugs and open study protocols, to people with life-threatening illnesses who are not eligible for a clinical trial when no other effective therapy exists. Also called compassionate use.
Go to definitions in 21 CFR 312.34 and 21 CFR 312.36.
Adverse event described in package labels, brochures, protocols, and consent forms. Go to the NIAID Clinical Terms of Award.
Review of a research project by a designated voting member or members rather than an entire institutional review board, allowed for some low-risk research and minor changes to a study.
Second-level review of qualifying grant applications by a subset of advisory Council members a few weeks after initial peer review to enable NIAID to make awards earlier. To qualify, an application must rank within the payline and have no concerns identified by the study section or Council.
NIH Guide term for the date a funding opportunity announcement expires and moves to the Grants.gov archive. Expiration date differs from closing date. See the equivalent Grants.gov term: archive date.
Go to NIAID's Application portal.
NIH grant that funds novel scientific ideas, model systems, tools, agents, targets, and technologies that have the potential to substantially advance biomedical research.
R21s are not intended for new investigators, and there is no evidence that they provide a path to an independent research career. R21s are awarded for up to two years and are not renewable.
Also go to NIH's Exploratory/Developmental Research Grant Award (R21).
Research supported by a grant or contract and administered by an NIAID extramural program division:
Also see intramural.
Go to NIAID's Extramural and Intramural Research questions and answers and NIAID Organizational Charts.
Last Updated May 03, 2013
Last Reviewed April 02, 2012