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Strategy for NIH Funding
Strategy to Write the Research Plan · Highlight Significance and Innovation
Pages of Part 3. Write Your Application
On this resource page you will see that the primary audience for your application is your peer review group and learn how to write for the reviewers who are experts in your field and those who are experts in other fields.
Here we emphasize the importance of investigating committees and members before you write the application, or even before you pick a project, and how well a review roster correlates with the actual membership of the committee that will review your application.
Before reading the information in this part, you may want to first read about planning the application in Part 2.
While this document is geared toward the basic research project grant, the R01, much of it is useful for other grants.
(This section has factual information only; for advice on this topic, go to Our Advice below.)
Your scientific review group is the primary audience for your application.
NIH scientific review groups—also called study sections in the Center for Scientific Review (CSR)—are made up of mostly academic scientists who meet for roughly two days, three times a year.
The primary reviewer presents your application's topic, strengths, and weaknesses to the group, and other assigned reviewers may comment.
Study sections usually have about 20 peer reviewers, but all do not play equally critical roles. Three act on your behalf: your primary and secondary reviewers plus at least one additional reader.
They are chosen by the group's scientific review officer (SRO)—a federal scientist—because their expertise is closest to your field. You should not expect the other members of the study section to be experts in your field or familiar with your science.
Your assigned reviewers read your application thoroughly, write a critique before the meeting, and assign preliminary scores for each review criterion as well as an initial overall impact/priority score. (Read about scoring at How Reviewers Score Applications in Part 5.)
These initial remarks launch the group discussion, the basis for the overall impact/priority score that each of your reviewers gives your application. More than anything else, that score determines your application's funding fate. Read more about peer review in Part 5. Assignment and Review.
NIH encourages you to choose a study section you feel would appreciate your ideas. You may request a study section in your application cover letter. Don’t request reviewers by name—if you do, they could be disqualified!
Find study sections on CSR's Integrated Review Groups. Find roster links at the top of the study section pages.
You can also log in to the Commons about 30 days before the review meeting to find your study section's roster.
Read more and get advice at Investigate Committees and Members below.
(This section has advice only; you should also read the factual information above at Just the Facts.)
Study sections usually have about 20 peer reviewers, but all do not play equally critical roles for your application.
All writers shape their material to the understanding and tastes of their audience.
Shakespeare, for example, was not only a poetic genius but also a celebrated playwright in his day, whose popularity stemmed from writing plays that appealed to people from all walks of life.
As a writer of an NIH grant application, your audience is much smaller. In fact, the most important people to reach may total only three.
Focusing the spotlight on such a tiny group is a much easier job. The catch is to know who the players are and what they're looking for.
Secondarily, you'll need to capture the interest of your audience that's not on stage but still vital to your success.
If you haven't chosen a project yet, now is the best time to look into which study sections your application may fit.
Being reviewed by a group that appreciates your ideas is critical to your success. The more they are in sync with your research, the less application space you will need to describe its significance—leaving more space to convince them that you and your team are able to get the job done.
Read more about choosing a study section below in Investigate Committees and Members.
Broadly speaking, the primary audience for your application is its peer review group.
As is noted above, the primary and secondary reviewers (plus at least one reader)—we'll call them assigned reviewers—act on your behalf at the meeting by taking the following actions.
Note that all 20 reviewers will score the application—even those who didn't read it or are not well versed in your field.
In case you're wondering why review meetings work this way: it's just not feasible for everyone to read all applications.
Review meetings cover dozens, sometimes hundreds, of applications, meaning reviewers have thousands of pages to read. Serving as a volunteer reviewer for NIH does not replace a reviewer's day job, and many must peruse applications after work hours.
Because reviewers can't possibly read all the applications in depth in the limited time they have before the meeting, they rely on the expertise of the assigned reviewers to focus the discussion.
In the next section, we'll show you how to appeal to everyone and make advocates out of your assigned reviewers.
Write and organize the application so the primary reviewer can readily grasp what you are proposing and be well poised to explain it to the others.
In the various parts of the application, you'll use different approaches to reach out to your audience so you can accommodate different levels of knowledge about your techniques and field.
Your best strategy is to try to get as many people excited about your project as you can. You'll do that by:
It can't hurt to grab their attention and get them onstage too! Any reviewer is more likely to read your application if it is an intriguing area, has a well-thought-out title, and shows well-crafted Specific Aims. Addressing all your reviewers is key if you're proposing highly innovative research. For more on that, go to Getting a Grant for Innovative Research.
Think of an application as being in a relationship with the review committee.
As with all relationships, you have to take other peoples' perspective into account. The relationship is as much about them as it is about you. For that reason, you have to learn about your reviewers and what they are looking for, as we describe below in Investigate Committees and Members.
If your reviewers are at the top of your field, they will know where the opportunities are and have strong views about what research should be conducted to move the field forward. By looking at their research and talking to other experts in the field, you should have an idea of how to meet your reviewers expectations of your choice and execution of project.
Play to the house. Tell your reviewers why the Institute should fund you and why they should give you the best score by describing how your topic is high impact and your objectives worth pursuing.
Fire up your reviewers by convincing them of these key points.
Be aware that a grant application is not a scientific review article. It's more of a conversation that excites its participants into valuing your proposal as highly significant and worthy of our investment.
Besides stimulating enthusiasm and being persuasive, you will need to focus your reviewers' attention by leaving out any facts that do not make your case.
Expect your assigned reviewers to read your Research Strategy and other important parts of the application.
Target your assigned reviewers. Help your assigned reviewers become your advocate by building a strong case for your research and making it easy for them to perform.
Organize and write so your assigned reviewers can readily find and understand the goals, significance, and feasibility of your project. Make explaining your research easy by including lines they can deliver to the rest of the study section.
Don't take that step to mean that your assigned reviewers will gloss over your application. On the contrary, expect them to read your Research Strategy and other important parts closely. When you write, keep in mind that they will:
Don't neglect the others. During the roughly 15-minute discussion, members of the group will ask the assigned reviewers questions and skim parts of the application—most likely, the following:
So you'll write those sections to meet the needs of those reviewers who are experts in other fields. In addition to the points noted above under "Play to the house," be sure to use a level at which an intelligent reader can understand your work, as in a Scientific American article.
Checkpoint. As I write my application, check that:
After you have chosen a study section, determine how its membership may affect your writing.
Being reviewed by a group that appreciates your scientific perspective and project is critical to your success.
Your grant application makes the case that you are a scientist who is competent to lead an important research project. But as with anything, beauty is in the eye of the beholder: your reviewers must agree.
Be in sync with your reviewers. First and foremost, your reviewers need to share your perspective that the topic you chose is vital to your field.
The repercussions of not having the right reviewers are great, e.g., they may see the field as having other priorities (you chose the wrong project) or believe that the research you proposed is too far out of the mainstream (the project is too innovative).
So it's critical to choose an NIH review committee that would embrace both your field and the direction in which you are planning to take your research.
Here's how to find the committees and people.
Spending time exploring the perspectives of different review committees and their members will help guide you at all of these steps:
This process is iterative; read more in Pick a Research Project in Part 2.
How to proceed with the search. Look at the rosters online, and find a committee with some people who will appreciate your research and share your scientific perspective. Be aware that this process is not perfect: the Center for Scientific Review may reconfigure study sections, use ad hoc reviewers, or (more rarely) not honor your request.
But even though there's no guarantee that the same people will review your application, it's important to see who may be on the committee, so you can learn the possible perspectives they and their peers have on your area of science.
Next, read their publications that are important to your field so you can write your application with those perspectives in mind, acknowledging that there are other points of view.
Forge ahead, following these guidelines.
Keep looking until you find the right audience for your application. Go to NIH's RePORTER to search for funded projects, experts and their grants, and the study sections that reviewed their applications.
To search for a study section, go to the Center for Scientific Review and review Integrated Review Groups. Find roster links at the top of the study section pages.
Note that in the following situations, your application will be assigned to a special emphasis panel, so you may not be able to find a roster in the Commons or elsewhere online until close to 30 days before the review meeting:
When CSR does post the rosters, it often aggregates several panels into one list to ensure reviewer confidentiality. Contact your scientific review officer with questions about your assignment, such as the review date and areas of expertise on the panel.
If you have a multidisciplinary application and don't see all the expertise on the roster, don't assume CSR will add it, so write for those reviewers who are experts in other fields.
Gauge the effect on your writing. After you have picked a study section, determine how its membership will affect your writing.
Try to figure out who could be your assigned reviewers, so you can tailor your writing to them (or others who may be present at the meeting with comparable expertise). To learn more about their research, go to their Web sites, and read their publications.
Ask these questions:
Depending on the answer to those questions, define the level of detail to include in the application about the significance and innovation of the research.
If you have a multidisciplinary application and don't see all the expertise on the roster, don't assume CSR will add it. Instead, write for those reviewers who are experts in other fields by avoiding technical jargon.
Ask investigators working in a different field from yours to read your application and give you feedback on readability.
Note any competitors. Look for reviewers who cannot give your application an impartial review.
This is not to say you should categorically avoid competitors. If you can trust them to stay objective, they may actually help you since they already know your field and appreciate the significance of your research.
However, if you believe the study section has appropriate expertise but you're concerned about a particular reviewer, you can inform your scientific review officer when you apply. NIH will make sure your application receives a fair review.
In your application cover letter, you will request the study section you've selected. You'll also have an opportunity to note what expertise is needed to understand your research and mention any reviewers who should not review your application. Read more at Create a Cover Letter in Part 4.
All this research into study sections and members takes time but is well worth it—you have a major stake in the people you choose to review your application.
To read more about the peer review process, go to Part 5. Assignment and Review, including Ensure You Get the Right Assignments.
Strategy for NIH Funding
See the other sections ofPart 3. Write Your Application
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Last Updated September 26, 2014
Last Reviewed June 29, 2012