See the Glossary for terms.
NIH published this RFA in an April 4, 2012, Guide notice.
Yes. Applicants should describe the Specific Aims in a one-page attachment, concisely stating the goals and expected outcomes, including the potential impact on the field. In the 12 pages of the Research Strategy, applicants should clearly describe how they plan to achieve the Specific Aims of the project and the organizational structures, roles, and responsibilities of the U.S. PD(s)/PI(s) and NFSC collaborative partners in accomplishing the proposed research.
The RFA instructs applicants to include a description of the collaborative research, detailing the integration of the U.S. and Chinese collaborative efforts.
This same application, including details of the work done by the U.S. PD/PI and China collaborator, will also be reviewed confidentially during the NSFC review process.
NIH will not consider accepting late applications for this RFA.
No. Early stage and new investigators will not receive any special consideration.
In the cover letter, applicants should clearly indicate the area of science proposed in the application and the preferred NIH institute. Applicants proposing research involving HIV/AIDS should indicate NIAID as the preference.
No. U.S. applicants should work closely with their Chinese collaborating investigators, who are responsible for obtaining the necessary approvals.
If the proposed research requires exporting biospecimens from China, U.S. applicants must include the following information in their applications:
In addition, a Material Transfer Agreement (MTA) may be needed for exchange of materials between two institutions. Contact the authorized organizational representative (AOR) at both organizations for institutional requirements (e.g., intellectual property issues). Also work with the AORs to address federal regulations for each country (e.g., customs.)
A U.S. investigator and Chinese collaborator work together to create a joint application that they submit to their respective agencies as follows:
The Chinese collaborator should check the NSFC Funding Opportunity Announcement (in Chinese) for additional information.
This RFA allows multiple PIs, which means more than one principal investigator at one or more institutions. Each is a full-fledged PI who has responsibilities appropriate to that role. There should be only one U.S. contact PI. Include a leadership plan for a multi-PI application.
Yes. You may submit a multi PD/PI application, but for this RFA all PDs/PIs should be U.S. investigators and name the Chinese investigator as a collaborating partner.
Though not a requirement, NIH strongly encourages you to provide a biographical sketch for all Senior/Key Personnel.
Applicants in response to this FOA must use the R&R (detailed) budget. If you receive a warning that the wrong budget format is being used, you may ignore it because warnings will not stop the validations process. If the modular budget is used, an error will occur and the application will not pass validations.
At this time, it is not clear if this RFA will be reissued in the future.
Yes, you must complete the human subjects section in the application if you or your collaborator in China will be doing research involving human subjects. Similarly, if you or your Chinese collaborator is planning to work on animals, you should complete the Vertebrate Animal section in the application.
Applicants and collaborating partners are expected to adhere to NIH regulations for the conduct of research involving human subjects and vertebrate animals.
Applications in response to this RFA will be reviewed based on the review criteria in the RFA, not like a traditional R01. As stated in the RFA, "Since a principal aim of this FOA is to attract and support new ideas, a key feature of this FOA is that preliminary data, unlike as in standard R01 applications, are not required for this R01 submission."
No. You cannot submit a closely related application for an independent R01 before a funding decision is made for this application. As explained in the May 15, 2009, Guide notice, NIH will not accept similar grant applications with essentially the same research focus from the same applicant organization.
The China component is extremely important. The application is incomplete without the China component and would not be peer reviewed without it. U.S. applications and NSFC (Chinese) applications will be received and reviewed independently by NIH and NSFC respectively before funding decisions are made.
No. These R01s are not percentiled because the applications are received and reviewed in response to the RFA. Applications in response to an RFA are usually funded based on the priority score and programmatic importance.
Funding decisions for applications submitted to NIH will be made by NIH based on merit with consideration of the research priorities of the U.S.-China program and in consultation with the NIH-NSFC Executive Secretariat. In the parallel processes conducted by NIH and NSFC, both the U.S. and Chinese applications must be determined to be eligible and responsive to be considered for funding under the program.
No. You do not need to have an active NIAID or NIH R01 to be eligible to submit an application in response to the RFA.
Yes. Submit the Letter of Support to grants.gov as a PDF. A scanned copy of hard signatures is acceptable.
There is no set limit to the amount of travel funds that the U.S. applicant can request. However, the total cost is already capped at $200,000 and the U.S applicant would need to justify the requested budget. Reviewers will also consider whether the budget and the requested travel funds are justified and reasonable.
No, it is not required. However, NIH encourages U.S. investigators to include this information, as well as a budget for any activities that they plan to undertake in China, as separate, clearly marked attachments to their NIH applications (in English). Use the Other Attachments option on the Research and Related Other Project Information form. Do not use NIH application budget forms for the Chinese budget.
All applications, regardless of the amount of direct costs requested for any one year, should include a data sharing plan. Applications should follow the NIH Data Sharing Policy and Implementation Guidance.
For applications proposing research on Parkinson's disease (PD) on U.S. patients:
Applications will not be evaluated for scientific and technical merit in study sections at the Center for Scientific Review. Instead, NIH will assign applications to scientific review groups (special emphasis panels) convened by NIAID, National Cancer Institute, National Institute of Mental Health, and National Institute of Neurological Disorders and Stroke, in accordance with NIH peer review policy and procedures, using the review criteria listed in the April 4, 2012, Guide notice. Applicants can see their review assignments in the eRA Commons after they apply.
Each of the participating institutes (ICs) will review applications. NIAID will review all HIV/AIDS applications.
No. U.S. institutions and Chinese collaborators can conduct their research in either country or both. However, the U.S. and Chinese investigators must demonstrate that they are collaborative partners in accomplishing the research. In addition, the U.S. component can be conducted at other foreign sites provided that there is a U.S.-Chinese collaboration in the proposed research.
The U.S.-China Program for Biomedical Collaborative Research stimulates collaborative basic, translational, and applied research between investigators from the U.S. and China in allergy, immunology, and infectious diseases, including HIV/AIDS and its comorbidities and coinfections, cancer, mental health, Parkinson’s disease, and stroke.
U.S. and Chinese investigators work together to identify projects that address the research objectives and funding requirements described in the April 4, 2012, Guide notice.
NSFC is the National Natural Science Foundation of China. For more information, visit NSFC's Web site in Chinese or English.
Chinese collaborators must be current or former NSFC grantees. For a searchable database of funded NSFC investigators (in Chinese), go to NSFC's Internet-based Science Information System.
Potential collaborators and scientists in Special Administrative Regions of China (e.g., Hong Kong) should contact NSFC to discuss their eligibility requirements.
For more details on eligibility requirements for Chinese collaborators, go to the NSFC Funding Opportunity Announcement (in Chinese).
Read the April 4, 2012, Guide notice and note the following:
No. Foreign institutions and non-U.S. components of U.S. organizations may not apply for funding.
Applications must list at least one investigator from a U.S. institution as the Program Director/Principal Investigator, and name the Chinese investigator as a collaborating partner.
Yes. Note that federal institutions must ensure that their authorizing legislation allows them to receive NIH grants and comply with the terms and conditions of an NIH award.
Contact your agency to find out if it is eligible.
No. However, they may apply to a separate U.S.-China Program for Biomedical Research Cooperation.
For more information, contact:
This initiative supports research areas outlined in the Funding Opportunity Description in the April 4, 2012, Guide notice. It does not support the following research activities:
Possibly, depending on the research focus (as indicated for each participating NIH institute) and its relevance to the intent of this initiative.
Before submitting their applications, U.S. investigators should discuss research plans with a Scientific/Research Contact listed under Agency Contacts in the April 4, 2012, Guide notice.
Note, however, that certain restrictions to permissible scientific activities are defined in the announcement.
Only if they include this information in their applications. PIs concerned about confidentiality or proprietary information should take the sharing requirement into account when deciding what information to include.
No. Only applicants can send this information to their collaborators.
U.S. applicants can request up to $200,000 a year in total costs (direct plus facilities and administrative costs) for up to three years.
Chinese collaborators can ask for up to 3 million renminbi over three years.
Yes. U.S. applicants can spend funds in China under this announcement but should justify in their applications why such an expense is needed to complete their research projects. Further, a U.S. investigator's budget should not overlap with that of his or her Chinese collaborator.
Before submitting an application, applicants should discuss budgets that propose to spend funds in China with a Scientific/Research Contact listed under Agency Contacts in the April 4, 2012, Guide notice.
U.S. institutions do not pay for facilities and administrative costs for their Chinese collaborators. However, they can include items needed at any foreign site (whether in China or elsewhere) as direct costs in their budgets.
Chinese collaborators receive support directly from NSFC.
For more information on calculating facilities and administrative costs on an NIH grant, contact your institution's business office and read Where do I find guidance on calculating facilities and administrative costs? in our Managing a Grant questions and answers.
No. Documents must have original signatures, which are then scanned and submitted.
Yes, they will receive feedback in the form of summary statements after peer review of their applications.
NSFC will review applications from Chinese collaborators using review criteria that match NIH's.
Yes. Reviewers will evaluate all investigators for appropriate scientific background to conduct the proposed research.
Though not a requirement, NIH strongly encourages it.
Yes, as long as the applications are scientifically distinct. Note that NIH will not accept any application that is essentially the same as one already reviewed or pending initial peer review.
Contact the appropriate Scientific/Research Contact listed under Agency Contacts in the April 4, 2012, Guide notice.
If you didn't find your question here, we also have general Peer Review at NIAID questions and answers.
Last Updated September 05, 2012
Last Reviewed September 05, 2012