See the Glossary for more terms.
NIH published this funding opportunity announcement (FOA) in a December 13, 2013, Guide notice.
The questions and answers below are for the R21 opportunity. For those applying for the R01 or U01 companion FOA, see the following:
Yes. To be eligible, the South African institution must meet the following criteria. The institution must be:
If you have any questions regarding the eligibility of your South African institution, contact Arlene Smith (firstname.lastname@example.org) at the South African Medical Research Council (MRC).
Though you can't be a PI, you can still be part of the proposed project as key personnel.
Yes. NIH encourages new investigators, especially early-stage investigators (ESIs), to apply.
To find out whether you qualify as new or ESI, go to How to Qualify for New and Early-Stage Investigator Status in our New Investigator Guide to NIH Funding.
Yes. Since you had children after completing your terminal degree, you would likely get an ESI extension of one year (six months for each child). For information on requesting permission for an extension, go to How do I request an extension of my ESI status? on NIH's Frequently Asked Questions About the NIH ESI Policy page.
Yes. See the International Awards section of our Questions and Answers as well as other resources on our International Awards portal.
Yes. Go to the Small and Exploratory/Developmental Research Grants, R03, R21, R21/R33 section of our Other Grant Types portal.
Yes. Applications must include at least one PD/PI affiliated with a U.S. institution and one PD/PI affiliated with an eligible South African institution (see next question). If they do not, applications will be considered nonresponsive and will not be reviewed.
Yes. It must be an eligible National Research Foundation (NRF) South African institution, defined as a legally constituted public higher education institution or organization wherein research is one of the primary purposes for its existence, including the training of postgraduate students.
No. As long as the PD/PI is a full-time employee of an eligible South African institution or under a long-term contract for the duration of the award, he or she is eligible. Keep in mind that it's important to document this in the application.
No. Investigators from both countries will work together to prepare and submit one application, which should follow the multiple PI approach. See next question.
For a multiple PI application, you should know that:
For more information, read Multiple PI Facts in the Strategy for NIH Funding, but note that the Facts refer to investigator-initiated applications so some of the information does not apply in this case.
For the R01 and R21 together, NIH plans to commit approximately $8 million to fund up to 25 awards this fiscal year (FY 2014).
Yes. The combined budget for direct costs for the two-year project period may not exceed $275,000, and no more than $200,000 may be requested in any single year. At least 50 percent of the total budget costs must support the South African institution.
To see what research areas related to HIV/AIDS and TB are of interest, read the examples in the Research Objectives section of the FOA. Keep in mind that these are broad topics under which your proposed project may fall.
If you'd like to know whether your research is appropriate (i.e., responsive) for this FOA, contact the Scientific/Research Contact(s) listed in the announcement. Consider submitting an optional letter of intent (LOI), which is due a month before the application. Learn more about LOIs in our December 19, 2013, Funding Newsletter article "Why Writing Letters of Intent Helps Us Help You."
Clinical trials (stage I, II, III, or IV) are not allowed through this FOA. Applications proposing trials will be deemed nonresponsive and will not be reviewed.
No. As with applications that propose clinical trials, those that include the use of select agents will be nonresponsive to this FOA and will not be reviewed.
For a list of what is considered a select agent, go to HHS and USDA Select Agents and Toxins, and to see if an agent is exempt or excluded, see Select Agent Exclusions. Find other resources at NIH's Select Agent Information.
Contact the Scientific/Research Contact(s) listed in the FOA.
Last Updated February 21, 2014
Last Reviewed February 21, 2014