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PHS 2590 Progress Report SOP

Lock icon: This link will not work for public visitors.Some links will work for NIAID staff only.

This standard operating procedure (SOP) includes the following sections: Purpose, Procedure, Contacts, and Links.


To document progress of a grant through a PHS 2590 noncompeting progress report and document a program officer's evaluation of the progress report in IMPAC.


Except for those with multiyear awards, NIH grantees must submit annual reports describing scientific progress and identifying changes in objectives, scope, or key personnel.

Multiyear awards receive all funding in the first year and have different rules. For more information, go to NIH Instructions for Progress Reports for Multiyear Funded (MYF) Awards.

NIH does not notify grantees that a progress report is late, and may delay awards if reporting elements are not complete.

NIAID program officers review each progress report to determine whether NIAID will continue funding a project, and NIAID grants management specialists evaluate each grant's administrative and fiscal status. Both must approve a progress report before NIAID can issue an award.

Find more information in Understand the Annual Progress Report in the Strategy for NIH Funding.

Note: This SOP covers progress reports for training, multiproject, foreign, and small business awards, as well as any other grants for which PIs are allowed to use the PHS 2590 form. For awards that require the Research Performance Progress Report (RPPR), go to the Research Performance Progress Report (RPPR) SOP.

Authorized Organizational Representative (AOR)

  • Find a list of due progress reports in the eRA Commons at Progress Report Search by Institutional Profile File (IPF) Number. To find your IPF number, use the IPF Number Search.
  • Secure a PI signature assurance and keep it on file.
  • Submit PI's progress report to NIH's central mailing address:

    National Institutes of Health
    6705 Rockledge Drive, Room 2207, MSC 7987
    Bethesda, MD 20892-7987 (use this ZIP code for the U.S. Postal Service, including express mail)
    Bethesda, MD 20817 (use this ZIP code for commercial carriers such as FedEx and UPS)


  • Use eRA Commons to get a list of progress reports, their due dates, and pre-populated face pages.
  • Sign and date a PI signature assurance that your business office keeps on file.
    • For multiple PI grants, investigators other than the contact PI must provide a separate signature assurance.
  • Submit a detailed budget if you anticipate significant rebudgeting.
  • Include My NCBI's official PDF list of publications in the Publications section.
  • Read PHS 2590 Non-Competing Continuation Progress Report forms and instructions to get complete details. Make sure you use the latest version.
  • For applications with multiple PIs, do the following:
    • Submit only one PHS 2590.
    • List the contact PI on the PHS 2590 Face Page and additional PIs on Form Page 1 Continued.
    • Ensure all PIs have a signature assurance on file with their institutions.
    • For changes to the leadership plan:
      • Mark "change" on the Progress Report Summary.
      • Describe changes to communication plans, procedures for resolving conflicts, and the administrative, technical, and scientific responsibilities for the PIs.
  • Once you have completed the PHS 2590, send it to your AOR for review, signature, and submission to NIH.

Program Officers

  • Review progress reports to do the following:
    • Evaluate scientific progress during the past budget period. Request additional information from the PI if necessary.
    • Determine whether there has been a change in scope due to documented changes in the use of human subjects.
    • Verify PIs have complied with public access rules.
    • Confirm that NIAID still has justification for funding the project.
  • Document your review and approval or disapproval of progress reports electronically using the Program Officer Checklist in IMPAC's Lock icon: This link will not work for public visitors. Program module (PGM).
    • For all grants except for T32s and T35s, generate Checklists by the 10th of the month before the grant anniversary date. For T32 and T35 grants, generate Checklists two and a half months before the start date.
    • Use the Program Signoff Notes section to document approval or disapproval of changes in staffing, personnel effort, changes in scope, or plans to use funds in the upcoming budget period. Identify issues that may require follow-up by a grants management specialist.
  • For step-by-step instructions on using the PGM to review progress reports, see Lock icon: This link will not work for public visitors.Complete a Program Official Checklist.
  • For more information on program officer responsibilities, see Lock icon: This link will not work for public visitors.NIH Policy Manual Chapter 54444, Evaluation of Grant Progress Reports by Program Officials.
  • Get an IMPAC account by completing the Lock icon: This link will not work for public visitors. IMPAC Registration Form.

Grants Management Specialists

  • Evaluate the grant's administrative and fiscal status.
  • Perform an administrative and fiscal evaluation using information in the progress report.
  • Access the Program Officer Checklist from the IMPAC Grants Management module.
    • Review the Checklist for the program officer's recommendations and for items that require follow-up.
    • Do not issue an award until all Checklist items are resolved.
  • For more responsibilities, GMP staff can see GMP's Lock icon: This link will not work for public visitors.Non-Competing Progress Reports (eSNAPs and SNAPs) SOP.


See the GMP Assignments by Geographic Region and Program Code for the appropriate GMP specialist.

Lock icon: This link will not work for public visitors.Contact for NIAID Staff

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Last Updated August 15, 2014

Last Reviewed August 15, 2014