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To ensure contracts comply with PHS and NIH policies involving the care and use of live vertebrate research animals.
To receive an NIH contract, offerors proposing work with live vertebrate research animals must base their animal care and use programs on the Guide for the Care and Use of Laboratory Animals and abide by the PHS Policy on Humane Care and Use of Laboratory Animals. PHS policy is summarized in the brochure What Investigators Need to Know About the Use of Animals.
NIH policy does not allow the award of a contract involving the use of live vertebrate animals to an offeror without an NIH Office of Laboratory Animal Welfare (OLAW)-approved assurance and valid institutional animal care and use committee (IACUC) approval unless OLAW provides special approval and the contract contains language restricting the use of animals.
Additionally, NIH policy requires evaluation of proposals as "acceptable" or "unacceptable" with regard to the five points stated in the Care of Live Vertebrate Animals provision in the technical proposal instructions of the solicitation.
Also see the following guidance:
Find more information at Animals in Research on the Research Funding Web site.
Offerors, see the Office of Acquisitions staff listing for the appropriate contract specialist.
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HHSAR 352.270-5 Care of Laboratory Animals
Institutional Animal Care and Use Committee Guidebook
OLAW Public Health Service Policy on Humane Care and Use of Laboratory Animals
What Investigators Need to Know About the Use of Animals
Vertebrate Animals in Research questions and answers
Disaster Planning and Response Resources: OLAW
Instructions for Completion and Technical Evaluation of the Vertebrate Animal Section (VAS) in NIH Contract Proposals
American Veterinary Medical Association (AVMA) Guidelines on Euthanasia
Last Updated December 13, 2013
Last Reviewed March 27, 2012