See the Glossary for more terms.
Some links will work for NIAID staff only.
This standard operating procedure (SOP) includes the following sections: Purpose, Procedure, Contacts, and Links.
To help scientists begin independent research earlier in their career.
The NIH Pathway to Independence Award (K99/R00) supports salary and research expenses in the mentored K99 phase for new investigators.
The R00 phase provides salary and fringe benefits to continue the research project independently. In the second phase the investigator must have a tenure-track, full-time assistant professor position or equivalent.
For non-U.S. citizen and permanent residents, the applicant institution is responsible for determining and documenting in the application that the applicant investigator's visa will allow him or her to remain in this country long enough to be productive on the research project in the U.S. for the duration of the proposed independent research (R00) phase.
An institute's intramural laboratory may use its funds to support the applicant during the K99 phase. Principal investigators who want to continue into the R00 phase must obtain an extramural institution position.
Note the following:
As with other K awards, investigators may request part-time appointments and other adjustments. For more information, see the Career Development Grants SOP.
For applications due on or after February 12, 2016, eligibility is restricted to people with a doctoral degree and no more than four years of postdoctoral training as of the relevant application due date regardless of whether the application is new or a resubmission. To be eligible to apply, you must be in a mentored, postdoctoral training position.
K99 Mentored Phase
R00 Independent Phase
For more information, GMP staff can see GMP's Pathway to Independence (K99-R00) Awards SOP.
Applicants with questions should read Communicating With NIAID—How to Get Help.
AITrainingHelpDesk@niaid.nih.gov—Office of Research Training and Special Programs
Chernay Mason for career (K) awards
Contact for NIAID Staff—Grants Management Career Award Coordinator
Contact for NIAID Staff—NIAID Budget Office
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Career Development Awards
Career Development Grants SOP
NIAID Training and Career portal
NIH's Pathway to Independence Award FAQs
Last Updated December 04, 2015
Last Reviewed February 11, 2013