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Applicati​on Resubmissions SOP

 This standard operating procedure (SOP) includes the following sections: Purpose, Procedure, Contacts, and Links.

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To enable investigators to resubmit their applications when their initial peer review results are not in the fundable range.


For unfunded applications, an investigator may resubmit an application once within 37 months of the application's original receipt date.

Resubmissions must address reviewer comments from the original application's summary statement.

Investigators and Applicants

  • Include an introduction that addresses the previous summary statement and indicate how your resubmission differs from the previous submission. For an electronic application, the introduction is a PDF attached to the PHS 398 Research Plan component.
  • Identifying individual changes in the text of specific aims, research strategy and other application attachments is no longer required (NOT-OD-15-030), though NIH will continue to accept applications that contain the specific mark-ups.
  • Indicate substantial scientific changes by outlining them in your introduction, summarizing substantial additions, deletions, and changes to the application as well as responding to major weaknesses raised in the summary statement.
    • Note: Identifying individual changes by using brackets, indents, or change of typography in the text of Specific Aims, Research Strategy, and other application attachments is no longer required, though NIH will continue to accept applications that contain the specific mark-ups.
  • If your application in response to a request for applications (RFA) did not succeed and you want to submit it again, you could convert it into a new investigator-initiated application.
  • Follow our advice for timing and other matters.
  • If you are not funded after the initial submission and one resubmission, you must submit a new research application. You may not address previous summary statement issues as a separate attachment in a new application.


Applicants with questions should read Communicating With NIAID—How to Get Help.

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If you have knowledge to share or want more information on this topic, email with the title of this page or its URL and your question or comment. Thanks for helping us clarify and expand our knowledge base.


NIH's Frequently Asked Questions about resubmissions

NIH Policy on Resubmission Applications—explains what NIH will allow after an unsuccessful resubmission

December 4, 2014 Guide notice: NIH Modification to Guidance on Marking Changes in Resubmission Applications

Strategy for NIH Funding


Last Updated August 02, 2015

Last Reviewed February 10, 2015