See the Glossary for more terms.
Some links will work for NIAID staff only.
This standard operating procedure (SOP) includes the following sections: Purpose, Procedure, Contacts, and Links.
To ensure contracts comply with PHS and NIH policies involving the care and use of live vertebrate research animals.
To receive an NIH contract, offerors proposing work with live vertebrate research animals must base their animal care and use programs on the Guide for the Care and Use of Laboratory Animals and abide by the PHS Policy on Humane Care and Use of Laboratory Animals. PHS policy is summarized in the brochure What Investigators Need to Know About the Use of Animals.
NIH policy does not allow the award of a contract involving the use of live vertebrate animals to an offeror without an NIH Office of Laboratory Animal Welfare (OLAW)-approved assurance and valid institutional animal care and use committee (IACUC) approval unless OLAW provides special approval and the contract contains language restricting the use of animals.
Additionally, NIH policy requires evaluation of proposals as "acceptable" or "unacceptable" with regard to the five points stated in the Care of Live Vertebrate Animals provision in the technical proposal instructions of the solicitation. For proposals that receive an "unacceptable" rating, NIAID and the offeror will resolve the issues in negotiations, as they may affect NIAID’s assessment of the risk of a proposal when determining best value.
Also see the following guidance:
Find more information at Animals in Research on the Research Funding website.
Offerors, see the Office of Acquisitions staff listing for the appropriate contract specialist.
Contact for NIAID Staff
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AVMA Guidelines for the Euthanasia of Animals
Disaster Planning and Response Resources: OLAW
HHSAR 352.270-5 Care of Laboratory Animals
Institutional Animal Care and Use Committee Guidebook
Instructions for Completion and Technical Evaluation of the Vertebrate Animal Section (VAS) in NIH Contract Proposals
OLAW Public Health Service Policy on Humane Care and Use of Laboratory Animals
U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training
Vertebrate Animals in Research Questions and Answers
What Investigators Need to Know About the Use of Animals
Last Updated May 19, 2015
Last Reviewed March 17, 2015