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To require institutions applying for animal research awards to comply with NIH policies for the care of research animals.
To receive PHS awards, applicants working with research animals must abide by the PHS Policy on Humane Care and Use of Laboratory Animals and follow the American Veterinary Medical Association Guidelines on Euthanasia.
They must also base their programs of animal care and use on the Guide for the Care and Use of Laboratory Animals. To clarify how to use this guide, NIH’s Office of Laboratory Animal Welfare (OLAW) issued Position Statements, including an Adoption and Implementation Plan.
PHS policy is summarized in the brochure What Investigators Need to Know About the Use of Animals.
PHS's definition of research animal use includes production of custom antibodies and animals obtained for their tissues. Read more at Applicability of the PHS Policy.
Applicants must follow instructions in the funding opportunity announcement. Contract offerors must follow instructions in the solicitation.
An application involving research animals must address the five points listed in the Vertebrate Animals Section of the Research Plan. If it does not, CSR or NIAID (depending on where it is reviewed) will designate it incomplete and code it accordingly. See Answer the Five Points in the Vertebrate Animals Section for more information.
For grants, certain animal research codes in IMPAC and on an application's summary statement indicate a bar to award that must be resolved before funding. For a list of codes, go to Research Animals Involvement Codes.
Find more information on animal research requirements at Animals in Research.
Applicants and grantees should go to Contact Staff for Help in the Strategy for NIH Funding to determine who to contact.
Offerors should ask the primary contact listed in the RFP. See the Extramural R&D Solicitations list, or, see the Office of Acquisitions staff listing.
Contact for NIAID Staff
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Vertebrate Animals in Research questions and answers
OLAW: Office of Laboratory Animal Welfare
Animal Welfare Assurance for Foreign Institutions
Grant Application, Electronic SOP
Grant Application, Paper SOP
Worksheet for Review of the Vertebrate Animal Section (PDF)
Last Updated March 05, 2013
Last Reviewed February 14, 2013