See the Glossary for more terms.
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To prevent NIAID from making an award before resolving scientific review group concerns about the care or use of research animals.
To receive a PHS award, investigators working with research animals must base their programs of animal care and use on the Guide for the Care and Use of Laboratory Animals and abide by the PHS Policy on Humane Care and Use of Laboratory Animals. There are no exemptions from the PHS policy.
PHS policy is summarized in the brochure What Investigators Need to Know About the Use of Animals. Applicants must follow NIH application instructions.
Missing or insufficient animal care and use information may adversely affect an application's overall impact score.
Peer review recommendations may prevent NIAID from making an award before animal care and use documentation is in place and concerns are resolved.
Bars to award must be resolved before we can fund animal research.
NIAID staff work with applicants and NIH's Office of Laboratory Animal Welfare (OLAW) to resolve animal-related bars to award.
If an institution does not have an animal welfare assurance from OLAW, NIAID will withhold funding until an assurance is in place.
Find more information on animal research requirements at Animals in Research on the NIAID Research Funding Web site.
An animal welfare code 20 indicates that the application requires administrative review, e.g., for a lack of an animal welfare assurance or a change of institutions.
To get this bar lifted:
An animal welfare code 44 indicates a bar due to scientific review group concerns.
To lift this bar:
Verification of IACUC review and approval is required for any application involving use of live vertebrate animals. Submission of an IACUC approval date is not required before review, but is a just-in-time requirement before award.
Note that the resolution of vertebrate animal concerns may result in protocol modifications that require re-review by the IACUC and an updated verification of IACUC approval. NIAID does not issue a restricted award when vertebrate animal concerns are unresolved, except at the end of the fiscal year with permission from OLAW.
End of year. At the end of a fiscal year, NIAID may make restricted awards to institutions that lack animal welfare assurances or IACUC approvals. However, OLAW does not permit NIAID to award applications with code 44 bars to award.
To make restricted awards at the end of a fiscal year, grants management staff do the following:
Applicants should contact their program officer to discuss bars to award.
Contact for NIAID Staff
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Animals in Research SOP
Bars to Grant Awards SOP
Institutional Animal Care and Use Committee Guidebook
Public Health Service Policy on Humane Care and Use of Laboratory Animals
Vertebrate Animals in Research questions and answers
Last Updated June 20, 2013
Last Reviewed September 19, 2012