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Multiproject Awards

Lock icon: This link will not work for public visitors.Some links will work for NIAID staff only.

Standard Operating Procedure Table of Contents


To provide grant funding to at least two related research projects.


You may apply for a multiproject grant in one the following two ways:

  • Respond to a P01, P30, P50, or U19 request for applications (RFA).
  • Submit an application for an investigator-initiated P01 program project grant.

P01 grants support multidisciplinary, long-term research programs headed by an investigator who brings in a group of other investigators to support the project and share resources. This is the only option that allows investigator-initiated applications—go to the NIAID Investigator-Initiated Program Project Applications (P01) FOA.

P30 center core grants that support shared resources and facilities for a multidisciplinary research team or group of investigators focusing on a common research topic. 

P50 grants are research center grants where a multidisciplinary group of investigators share a common research topic. They are solicited through RFAs.

U19 grants are cooperative agreements, requiring substantial involvement from agency staff. See NIAID's Lock icon: This link will not work for public visitors.Cooperative Agreements Staff Portal.

Please note that NIH's big grant policy applies to multiproject applications, as described below.


  • If you are responding to an RFA or program announcement, read it thoroughly for eligibility conditions.
  • Read the Guidance for Preparing a Multiproject Research Application for NIAID-specific instructions.
  • For an investigator-initiated P01 application, contact an NIAID program officer when still in the planning stage to assess the likelihood of our approval of your idea.
    • NIAID must approve your application before you apply, indicating that we agree to allow Center for Scientific Review to assign it here for possible funding.
    • Your application must include a cover letter from an NIAID program officer that approves the submission.
    • For an overview on submitting an application, see P01 Program Project Grants.
  • For any multiproject application, you must get an NIAID program officer's approval six weeks before submitting if your application requests direct costs of $500,000 or more in any year of the grant, even if none of the individual projects request that much.
    • If you are requesting close to $500,000, read our Big Grants SOP for guidance.
    • Even if you plan to request under $500,000, we strongly encourage you to discuss your idea with an NIAID program officer when still in the planning stage.

Program Staff

  • Document your approval by following the procedures in the Big Grants SOP.


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Program Announcements SOP

Request for Applications SOP

NIAID Guidelines for Determining Whether a Resubmitted Program Project Application Qualifies as New

Lock icon: This link will not work for public visitors.Decision Tree For Whether a Resubmission P01 Is a New Application


Last Updated May 29, 2013

Last Reviewed May 29, 2013