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Reassortment vs. Reverse Genetics

A comparison of the age-old method of making a flu vaccine with a new, more efficient technique.

Reassortment

View Reassortment Illustration showing how researchers use reassortment, which is the swapping and mixing of gene segments between two different viral strains inside a fertilized chicken egg, to create a new vaccine.
High resolution illustration is available for downloading

Reverse Genetics

View Reverse Genetics Illustration showing how researchers use reverse genetics to custom-make a flu strain to be incorporated into a vaccine.
High resolution illustration is available for downloading

Credit: These images are in the public domain. Please credit the National Institute of Allergy and Infectious Diseases (NIAID).

Last Updated December 03, 2006