Topical microbicides are preparations (for example, gels, creams, or foams) that are applied either vaginally and/or rectally to prevent sexually transmitted diseases such as HIV. Ideally, microbicides would be unnoticeable, fast-acting against HIV and a broad range of other sexually transmitted pathogens, inexpensive, safe for use at least one to two times daily, and easy to store.
A topical microbicide may prevent HIV transmission by
The main goal of the NIAID HIV Topical Microbicide Reseach Program is to support research that leads to identifying and developing safe, effective, and acceptable topical microbicides. NIAID’s topical microbicide research is outlined in the NIAID Topical Microbicide Strategic Plan, and includes basic research through preclinical development and clinical trials. Currently, the priority areas include:
Last Updated June 18, 2010
Last Reviewed March 26, 2010