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Topical Microbicides

Research Activities

NIAID has supported topical microbicide development through a broad-based Topical Microbicide Program guided by the NIAID Topical Microbicide Strategic Plan. The program is implemented through NIAID’s Division of Acquired Immunodeficiency Disease and the Division of Microbiology and Infectious Diseases Sexually Transmitted Diseases Branch. NIAID has also co-sponsored several microbicide research and development programs with the Eunice Kennedy Shriver National Institute of Child Health and Development (NICHD) and, more recently, with the National Institute of Mental Health (NIMH).

In addition, NIAID works with other government agencies and nongovernment agencies (for example, U.S. Agency for International Development, Centers for Disease Control and Prevention, and Contraceptive Research and Development) to coordinate activities and exchange scientific and technical information. Similarly, NIAID recently began a formal partnership with the International Partnership for Microbicides to increase sharing of information and expertise in an effort to develop topical microbicides. More information is available from the press release. Efforts to coordinate support for microbicide research and development among global funders is in the process of being formalized through a process initiated by the Bill & Melinda Gates Foundation and the Alliance for Microbicide Development.

  • HIV Prevention Trials Network (HPTN)
    Co-sponsored by NIAID, NICHD, NIMH, and the National Institute on Drug Abuse, HPTN is a worldwide collaborative clinical trials network that develops and tests the safety and efficacy of primarily non-vaccine interventions designed to prevent the transmission of HIV.
    More information about topical microbicide research in HPTN.
  • CRISP database
    This online database can be used to search for ongoing research supported by NIAID and the National Institutes of Health. (Keywords: Microbicide, HIV, or search for a specific microbicide or strategy.)
  • AIDSinfo
    This government website has information on HIV/AIDS-related health topics, treatment and prevention guidelines, information on drugs and vaccines, and a database of all federally funded HIV/AIDS clinical trials.

Additional Information

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Last Updated July 18, 2006

Last Reviewed March 26, 2010