NIAID conducts and supports research around the world that aims to find prevention and treatment methods for debilitating and deadly infectious diseases, including cholera.
Because the bacteria that cause cholera, Vibrio cholerae, is spread through contaminated water, cholera is not a public health issue in countries where drinking water and sewage are separated and treated.
It is unlikely that an outbreak of cholera would occur in the United States or other developed countries, but cholera epidemics are a very big public health concern in Haiti, India, and other developing areas of the world.
NIAID-supported scientists conducting basic cholera research are studying the genetics of V. cholerae, its evolution, and how it interacts with environmental factors. Vaccine and treatment researchers are exploring live and “killed” vaccine formulations and novel molecular and folk-based remedies for cholera.
Last Updated March 01, 2011
Last Reviewed January 24, 2011