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Finding a Cure for HIV/AIDS

Research to find a cure for HIV/AIDS is among NIAID top priorities. NIAID supports a large portfolio of investigator-initiated grants in HIV cure research to identify where HIV hides, known as the HIV reservoir, and to determine how these hideouts are established and maintained. In addition, NIAID also funds research to control and eliminate the viral reservoir.

Research Goals

  • Identify and characterize replication-competent HIV reservoirs throughout the body
  • Determine the effects of early antiretroviral treatment, chemotherapy and transplantation, latency reversal, immune modulation, cell and gene therapies, and other interventions on the HIV reservoir
  • Develop assays and model systems, including nonhuman primate and humanized mouse models, to quantify and study HIV latency
  • Identify which reservoirs serve as the source of viral rebound when antiretroviral therapy is stopped
  • Determine the role of HIV integration site and homeostatic proliferation on virus elimination strategies
  • Investigate strategies that lead to purging of the latent reservoir and a cure for HIV/AIDS or control of viral rebound and sustained remission

Funding Opportunities

For updates on potential HIV cure-related funding opportunities, see the latest DAIDS council-approved concepts.

Currently Active Grants (under RFAs and PAs only)

External Funding Opportunity Announcements

Scientific Meetings


What's New

All HIV/AIDS News Releases

News From NIAID-Supported Institutions​​​​​​​

Last Updated April 28, 2016