NIAID is supporting a number of vaccine trials around the world with a variety of organizations, centers, partnerships, and programs.
The Vaccine Research Center (VRC) at the National Institutes of Health (NIH) was established to facilitate research in vaccine development. VRC is dedicated to improving global human health through the rigorous pursuit of effective vaccines for human diseases.
Formed in 1999 by NIAID, the HIV Vaccine Trials Network (HVTN) is an international collaboration of scientists and educators searching for an effective and safe HIV vaccine. HVTN mission is to facilitate the process of testing preventive vaccines against HIV/AIDS. Our organization conducts all phases of clinical trials, from evaluating experimental vaccines for safety and the ability to stimulate immune responses, to testing vaccine efficacy. Led by investigators and powered by collaborators, HVTN conducts its research through multicenter clinical trials in a global network of domestic and international sites. Organized by committee and intellectual discipline, the investigators develop, discuss, implement, analyze, and prioritize both vaccine design concepts and studies. Protocols are developed by HVTN investigators and include partnerships between vaccine developers, clinical experts, and biostatisticians. HVTN works closely with NIH staff in initiating, conducting, funding, and coordinating all vaccine development processes.
The Partnership for AIDS Vaccine Evaluation (PAVE) is a voluntary consortium of U.S. government agencies and U.S. government-funded organizations involved in HIV vaccine research. Members of PAVE include NIH, HVTN, VRC, U.S. Military HIV Research Program, and Centers of Disease Control and Prevention.
The Center for HIV/AIDS Vaccine Immunology (CHAVI) was established by the NIAID Division of AIDS (DAIDS) as part of the Global HIV/AIDS Vaccine Enterprise. It aims to elucidate basic sciences questions and conduct early phase clinical trials of HIV vaccine candidate at clinical sites around the world. Dr. Barton Haynes of Duke University serves as the principle investigator of CHAVI’s scientific leadership group.
Established in 1985 to protect troops entering endemic HIV areas, the U.S. Military HIV Research Program (USMHRP) brings together scientists from the Army, Navy, and Air Force. DAIDS jointly plans and executes HIV/AIDS research projects with the USMHRP through an interagency agreement.
This is a virtual consortium of organizations committed to the development of a preventive HIV/AIDS vaccine. It implements shared scientific plans, mobilize resources, and improve worldwide collaborations.
The International AIDS Vaccine Initiative (IAVI) was founded in 1996 to speed discovery of an HIV vaccine. IAVI partners worldwide with private companies, academic institutions, and government agencies, such as NIH.
For a list of all federally funded vaccine studies, please visit AIDSinfo.
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Last Updated February 08, 2006