Primary Immune Deficiency Diseases

Major Primary Immune Deficiency Diseases Studied by NIAID

We currently support research for the following primary immune deficiency diseases:

• Autoimmune Lymphoproliferative Syndrome (ALPS)
• Chronic Granulomatous Disease (CGD)
• Common Variable Immunodeficiency (CVID)
• DiGeorge Syndrome
• Hyper-Immunoglobulin E Syndrome (also known as Job’s Syndrome)
• Hyper-Immunoglobulin M (Hyper-IgM) Syndrome
• Leukocyte Adhesion Deficiency (LAD)
• NF-κB Essential Modifier (NEMO) Mutations
• Selective Immunoglobulin A (IgA) Deficiency
• Severe Combined Immunodeficiency (SCID)
• Wiskott-Aldrich Syndrome (WAS)
• X-Linked Agammaglobulinemia (XLA)
• X-Linked Lymphoproliferative Disease (XLP)