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Primary Immune Deficiency Diseases (PIDDs)​

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Quick Facts

  • Primary immune deficiency diseases are due to genetic factors; PIDDs should not be confused with secondary or acquired immune deficiencies, which are caused by something outside the body such as a virus or immune suppressing drugs.
  • An estimated 500,000 Americans are afflicted with PIDDs; 5,000 to 10,000 are severely affected.
  • There are more than 200 different forms of PIDDs; almost all of these diseases are considered rare (each affecting fewer than 200,000 people in the United States).
  • Because of the high level of recurring infections in affected people, morbidity, mortality, and medical costs are high.
  • With proper surveillance, many of these diseases can be detected and effectively treated or managed in infancy and early childhood.

Last Updated December 05, 2014