Skip Navigation

Primary Immune Deficiency Diseases

Skip Content Marketing
  • Share this:
  • submit to facebook
  • Tweet it
  • submit to reddit
  • submit to StumbleUpon
  • submit to Google +

Quick Facts

  • Primary immune deficiency diseases (PIDDs) are due to genetic mutations that are inherited; PIDDs should not be confused with secondary or acquired immune deficiencies, which are caused by something outside the body such as a virus or immune suppressing drugs.
  • An estimated 500,000 Americans are afflicted with PIDDs; 5,000 to 10,000 are severely affected. 
  • There are more than 150 different forms of PIDDs; almost all of these diseases are considered rare (affecting fewer than 200,000 people in the United States).
  • Because of the high level of recurring infections in affected people, morbidity, mortality, and medical costs are high.
  • With proper surveillance, many of these diseases can be detected in infancy and early childhood.

Last Updated July 17, 2012

Last Reviewed September 15, 2009