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Primary Immune Deficiency Diseases (PIDD)

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Clinical Studies in Primary Immune Deficiency Diseases

Our clinical studies are aimed to better understand the causes, complications, and disease course of primary immune deficiency diseases (PIDDs) and investigate new therapies and preventions.

Laboratory of Clinical Infectious Diseases

  • Immunopathogenesis Section
    Examine immune cell defects in chronic granulomatous disease, hyper-immunoglobulin E (Job’s) syndrome, leukocyte adhesion deficiency, GATA2 deficiency, CTLA4 deficiency, and STAT1 deficiency
  • Fungal Pathogenesis Unit
    Examine immune and microbiologic features associated with candidiasis and APECED syndrome

Laboratory of Host Defenses

NIAID PID Clinic

  • Provide thorough examination, diagnosis, and treatment recommendations for individuals and families affected by PIDDs
  • Offer eligible individuals the opportunity to participate in an ongoing clinical trial at NIAID or outside NIAID

Laboratory of Immunology

  • Clinical and Molecular Genomics Unit
    Investigate the molecular, cellular, and immunological mechanisms of genetic diseases of the immune system and attempt to discover new therapeutic approaches based on this knowledge

Laboratory of Allergic Diseases

  • Genetics and Pathogenesis of Allergy Section
    Study patients with allergic disease that is part of a syndrome, often immune deficiency, and why defects in the molecules that cause the disease also cause allergic disease.
  • Food & Allergy Research Unit
    Investigate the genetic and immunologic pathways that lead to food allergy and related conditions

Laboratory of Molecular Immunology

  • Molecular Signaling Section
    Develop new treatments for WHIM syndrome and related disorders based on precise understanding of the underlying genetic, biochemical, and cellular mechanisms of disease

Last Updated December 05, 2014

Last Reviewed October 04, 2009