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NIAID Role in Lupus Research

NIAID-supported research on autoimmune diseases, including lupus, focuses on

  • Developing a greater understanding of the fundamental biologic principles underlying disease onset and progression
  • Developing improved animal and in vitro models of disease
  • Devising improved diagnostic tools
  • Creating more effective interventions and preventive strategies
  • Identifying the epidemiologic profiles of autoimmune diseases

NIAID-supported studies have used cutting-edge technologies to perform genetic analyses comparing large cohorts of people with autoimmune diseases to healthy control subjects. These studies have revealed new genetic risk factors for individual autoimmune diseases including systemic lupus erythematosus (SLE), as well as gene variants that predispose a person to more than one autoimmune disease. Recently, researchers found three new genetic loci for SLE.

Last Updated February 25, 2009

Last Reviewed February 25, 2009