Health experts recommend antibiotics if you have been exposed to wild rodent fleas, during a plague outbreak in animals, or to a possible plague-infected animal. Because there are so few cases of plague in the United States, experts do not recommend taking antibiotics unless it's certain a person has been exposed to plague-infected fleas or animals.
Currently, there is no commercially available vaccine against plague in the United States.
Last Updated January 15, 2015
Last Reviewed January 15, 2015