BAA-NIAID-DAIT-NIHAI2013166 - Development of Medical Countermeasures to Enhance Platelet Regeneration and Survival Following Radiation Exposure from a Radiological/Nuclear IncidentDue Date July 1, 2013
Request for Information (Department of the Army – Solicitation #W911QY-13-S-0003): Identification of Radiological Diagnostic Devices. Due Date: March 26, 2013.
DARPA-SN-13-24: Reducing Ionizing Radiation Risk (RFI). Receipt date April 2, 2013.
FDA BAA-12-00118: Food and Drug Administration Broad Agency Announcement for the Advanced Research and Development of Regulatory Science and Innovation. Continuously open announcement valid through May 22, 2013.
BARDA-CBRN-BAA-12-100-SOL-00011: Advanced Research and Development of Chemical, Biological, Radiological, and Nuclear Medicine Countermeasures
In the aftermath of an incident in which a significant number of civilians are exposed to radiation or radioactive materials, health authorities will need to be able to rapidly identify individuals who are contaminated externally with radioactive material, have incorporated radioactive material into their bodies, or have been exposed to medically significant doses of radiation. Detecting radioactive contamination is the easier task, because powerful technologies for detection and quantitation of even small amounts of radioactive materials already exist. For example, Geiger counters or doorframe/portal monitors can detect the presence of many radioactive materials and can thus help to identify individuals who must be decontaminated immediately after any necessary medical stabilization of trauma or burn injury. Monitoring of blood or urine samples for radioactivity also can be used to reveal the presence of internalized radioactive material.
Although radioactive material can be detected with instruments, assessment of the dose of radiation a person has already received, such as from gamma radiation released by the detonation of a nuclear device, is more difficult. Radiation exposure can be assessed through clinical history, signs, symptoms, and laboratory tests such as lymphocyte counts and dicentric chromosome assays. These methods are not currently adequate for a mass-casualty scenario as signs and symptoms can be misleading and laboratory tests are time-consuming and expensive.
NIH plans to pursue the goals in this research area primarily through the Centers for Medical Countermeasures Against Radiation program. Examples of research and development areas to be addressed in these centers include:
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Last Updated April 07, 2010