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Radiation and Nuclear Countermeasures Program

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Medical Countermeasures Against Radiological Threats (MCART) Publications

2014

MacVittie TJ. The MCART consortium animal models series: an evolving MCART. Health Phys. 2014 Jan;106(1):1-6.  

Plett PA, Chua HL, Sampson CH, Katz BP, Fam CM, Anderson LJ, Cox GN, Orschell CM. PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome. Health Phys. 2014 Jan;106(1):7-20.  

Chua HL, Plett PA, Sampson CH, Katz BP, Carnathan GW, MacVittie TJ, Lenden K, Orschell CM. Survival efficacy of the PEGylated G-CSFs Maxy-G34 and neulasta in a mouse model of lethal H-ARS, and residual bone marrow damage in treated survivors. Health Phys. 2014 Jan;106(1):21-38.  

Farese AM, Brown CR, Smith CP, Gibbs AM, Katz BP, Johnson CS, Prado KL, MacVittie TJ. The ability of filgrastim to mitigate mortality following LD50/60 total-body irradiation is administration time-dependent. Health Phys. 2014 Jan;106(1):39-47.  

Jackson IL, Xu PT, Nguyen G, Down JD, Johnson CS, Katz BP, Hadley CC, Vujaskovic Z. Characterization of the dose response relationship for lung injury following acute radiation exposure in three well-established murine strains: developing an interspecies bridge to link animal models with human lung. Health Phys. 2014 Jan;106(1):48-55.  

Garofalo M, Bennett A, Farese AM, Ward A, Taylor-Howell C, Cui W, Gibbs A, Lasio G, Jackson W 3rd, MacVittie TJ. The delayed pulmonary syndrome following acute high-dose irradiation: a rhesus macaque model. Health Phys. 2014 Jan;106(1):56-72.  

Garofalo MC, Ward AA, Farese AM, Bennett A, Taylor-Howell C, Cui W, Gibbs A, Prado KL, MacVittie TJ. A pilot study in rhesus macaques to assess the treatment efficacy of a small molecular weight catalytic metalloporphyrin antioxidant (AEOL 10150) in mitigating radiation-induced lung damage. Health Phys. 2014 Jan;106(1):73-83.  

MacVittie TJ, Bennett AW, V Cohen M, Farese AM, Higgins A, Hankey KG. Immune cell reconstitution after exposure to potentially lethal doses of radiation in the nonhuman primate.
Health Phys. 2014 Jan;106(1):84-96

Kazi AM, MacVittie TJ, Lasio G, Lu W, Prado KL. The MCART radiation physics core: the quest for radiation dosimetry standardization. Health Phys. 2014 Jan;106(1):97-105.  

Jones JW, Scott AJ, Tudor G, Xu PT, Jackson IL, Vujaskovic Z, Booth C, MacVittie TJ, Ernst RK, Kane MA. Identification and quantitation of biomarkers for radiation-induced injury via mass spectrometry. Health Phys. 2014 Jan;106(1):106-19.  

Scott AJ, Jones JW, Orschell CM, MacVittie TJ, Kane MA, Ernst RK. Mass spectrometry imaging enriches biomarker discovery approaches with candidate mapping. Health Phys. 2014 Jan;106(1):120-8.  

Dörr H, Lamkowski A, Graessle DH, Bennett A, Shapiro A, Farese AM, Garofalo M, MacVittie TJ, Meineke V. Linking the human response to unplanned radiation and treatment to the nonhuman primate response to controlled radiation and treatment. Health Phys. 2014 Jan;106(1):129-34.

2012

MacVittie TJ. The MCART Consortium Animal Models Series. Health Phys. 2012 Oct;103(4):340-2.

Plett PA, Sampson CH, Chua HL, Joshi M, Booth C, Gough A, Johnson CS, Katz BP, Farese AM, Parker J, MacVittie TJ, Orschell CM.  Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome. Health Phys. 2012 Oct;103(4):343-55.

Chua HL, Plett PA, Sampson CH, Joshi M, Tabbey R, Katz BP, MacVittie TJ, Orschell CM. Long-term hematopoietic stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome. Health Phys. 2012 Oct;103(4):356-66.

Farese AM, Cohen MV, Katz BP, Smith CP, Jackson W 3rd, Cohen DM, MacVittie TJ. A nonhuman primate model of the hematopoietic acute radiation syndrome plus medical management. Health Phys. 2012 Oct;103(4):367-82.

Booth C, Tudor G, Tudor J, Katz BP, MacVittie TJ. Acute gastrointestinal syndrome in high-dose irradiated miceHealth Phys. 103(4):383-399, October 2012.

Booth C, Tudor G, Tonge N, Shea-Donohue T, MacVittie TJ. Evidence of Delayed Gastrointestinal Syndrome in High-dose Irradiated MiceHealth Phys. 103(4):400-410, October 2012.

MacVittie TJ, Farese AM, Bennett A, Gelfond D, Shea-Donohue T, Tudor G, Booth C, McFarland E, Jackson W 3rd. The acute gastrointestinal subsyndrome of the acute radiation syndrome: a rhesus macaque model. Health Phys. 2012 Oct;103(4):411-26.

MacVittie TJ, Bennett A, Booth C, Garofalo M, Tudor G, Ward A, Shea-Donohue T, Gelfond D, McFarland E, Jackson W, Lu W, Farese AM. The Prolonged Gastrointestinal Syndrome in Rhesus Macaques: The Relationship Between Gastrointestinal, Hematopoietic, and Delayed Multi-organ Sequelae Following Acute, Potentially Lethal, Partial-body Irradiation. Health Phys. 2012 Oct;103(4):427-53.

McGurk R, Hadley C, Jackson IL, Vujaskovic Z. Development and dosimetry of a small animal lung irradiation platform.  Health Phys. 2012 Oct;103(4):454-462.

Jackson IL, Xu P, Hadley C, Katz BP, McGurk R, Down JD, Vujaskovic Z.  A Preclinical Rodent Model of Radiation-induced Lung Injury for Medical Countermeasure Screening in Accordance With the FDA Animal Rule. Health Phys. 2012 Oct;103(4):463-473.

Weber W, Doyle-Eisele M, Seilkop SK, Guilmette R. Biokinetics of Systemically Distributed 60Co in the Rat: An Experimental Model Useful in Evaluating Medical Countermeasures for Internal Contamination. Health Phys. 2012 Oct;103(4):474-83.

Miller G, Bertelli L, Klare K, Weber W, Doyle-Eisele M, Guilmette R. Software for Empirical Building of Biokinetic Models for Normal and Decorporation-affected Data. Health Phys. 2012 Oct;103(4):484-94.

Last Updated September 21, 2012

Last Reviewed September 21, 2012