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Centers for Medical Countermeasures against Radiation (CMCR) Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006

2014

Shvedova AA, Yanamala N, Kisin ER, Tkach AV, Murray AR, Hubbs A, Chirila MM, Keohavong P, Sycheva LP, Kagan VE, Castranova V.  Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. Am J Physiol Lung Cell Mol Physiol. 2014:306(2):L170-82.

Mak TD, Laiakis EC, Goudarzi M, Fornace AJ Jr. MetaboLyzer: a novel statistical workflow for analyzing Postprocessed LC-MS metabolomics data. Anal Chem. 2014:86(1):506-13.

Gopal R, Rangel-Moreno J, Fallert Junecko BA, Mallon DJ, Chen K, Pociask DA, Connell TD, Reinhart TA, Alcorn JF, Ross TM, Kolls JK, Khader SA. Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection. Am J Pathol. 2014: 184(1):55-63.

Swartz HM, Williams BB, Zaki BI, Hartford AC, Jarvis LA, Chen EY, Comi RJ, Ernstoff MS, Hou H, Khan N, Swarts SG, Flood AB, Kuppusamy P. Clinical EPR: unique opportunities and some challenges. Acad Radiol. 2014 21(2):197-206.

Stoyanovsky DA, Sparvero LJ, Amoscato AA, He RR, Watkins S, Pitt BR, Bayir H, Kagan VE. Improved spatial resolution of matrix-assisted laser desorption/ionization imaging of lipids in the brain by alkylated derivatives of 2,5-dihydroxybenzoic acid. Rapid Commun Mass Spectrom. 2014: 28(5):403-12.

Kanter DJ, O'Brien MB, Shi XH, Chu T, Mishima T, Beriwal S, Epperly MW, Wipf P, Greenberger JS, Sadovsky Y. The impact of ionizing radiation on placental trophoblasts. Placenta. 2014: 35(2):85-91.

2013

Ambrose M, Gatti RA. Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions. Blood. 2013: 121(20):4036-45.

Andón FT, Kapralov AA, Yanamala N, Feng W, Baygan A, Chambers BJ, Hultenby K, Ye F, Toprak MS, Brandner BD, Fornara A, Klein-Seetharaman J, Kotchey GP, Star A, Shvedova AA, Fadeel B, Kagan VE. Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase. Small. 2013: 9(16):2721-9, 2720.

Beyoğlu D, Imbeaud S, Maurhofer O, Bioulac-Sage P, Zucman-Rossi J, Dufour JF, Idle JR. Tissue metabolomics of hepatocellular carcinoma: tumor energy metabolism and the role of transcriptomic classification.  Hepatology. 2013: 58(1):229-38.

Botelho FM, Rangel-Moreno J, Fritz D, Randall TD, Xing Z, Richards CD. Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation. J Immunol. 2013: 191(3):1453-64.

Burnett AF, Biju PG, Lui H, Hauer-Jensen M. Oral interleukin 11 as a countermeasure to lethal total-body irradiation in a murine model. Radiat Res. 2013: 180(6):595-602.

Cherry JD, Williams JP, O'Banion MK, Olschowka JA. Thermal injury lowers the threshold for radiation-induced neuroinflammation and cognitive dysfunction. Radiat Res. 2013: 180(4):398-406.

Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D, Qiang Wang KZ, Zhu J, Klein-Seetharaman J, Balasubramanian K, Amoscato AA, Borisenko G, Huang Z, Gusdon AM, Cheikhi A, Steer EK, Wang R, Baty C, Watkins S, Bahar I, Bayır H, Kagan VE. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nat Cell Biol. 2013: 15(10):1197-205.

Cobanoglu MC, Liu C, Hu F, Oltvai ZN, Bahar I. Predicting drug-target interactions using probabilistic matrix factorization. J Chem Inf Model. 2013: 53(12):3399-409. Di YP, Tkach AV, Yanamala N, Stanley S, Gao S, Shurin MR, Kisin ER, Kagan VE, Shvedova A. Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes. Am J Respir Cell Mol Biol. 2013: 49(5):759-67.

Demidenko E, Williams BB, Flood AB, Swartz HM. Standard error of inverse prediction for dose-response relationship: approximate and exact statistical inference. Stat Med. 2013: 32(12):2048-61.

Dickson R, Kim JO, Huq MS, Bednarz G, Suyama J, Yealy D, Izadbakhsh M, Greenberger J. Interceptor and Phantom Trials of EDNS at UPMC. Health Phys. 2013: 105(5 Suppl 3):S199-208.

Down JD, Medhora M, Jackson IL, Cline JM, Vujaskovic Z. Do variations in mast cell hyperplasia account for differences in radiation-induced lung injury among different mouse strains, rats and nonhuman primates? Radiat Res. 2013: 180(2):216-21.

Forrester HB, Ivashkevich A, McKay MJ, Leong T, de Kretser DM, Sprung CN. Follistatin is induced by ionizing radiation and potentially predictive of radiosensitivity in radiation-induced fibrosis patient derived fibroblasts. PLoS One. 2013: 8(10):e77119.

Gamper AM, Rofougaran R, Watkins SC, Greenberger JS, Beumer JH, Bakkenist CJ. ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage. Nucleic Acids Res. 2013: 41(22):10334-44.

Goff JP, Shields DS, Wang H, Skoda EM, Sprachman MM, Wipf P, Garapati VK, Atkinson J, London B, Lazo JS, Kagan V, Epperly MW, Greenberger JS. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013: 41(11):957-66.

Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowicz VO, Steyn AJ, Babu S, Kaushal D, Zúñiga J, Vogl T, Rangel-Moreno J, Khader SA. S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. Am J Respir Crit Care Med. 2013:188(9):1137-46.

Grad M, Young EF, Smilenov L, Brenner DJ, Attinger D. A simple add-on microfluidic appliance for accurately sorting small populations of cells with high fidelity. J Micromech Microeng. 2013: 23(11).

Hyduke DR, Laiakis EC, Li HH, Fornace AJ Jr. Identifying radiation exposure biomarkers from mouse blood transcriptome. Int J Bioinform Res Appl. 2013:9(4):365-85.

Johnston CJ, Manning CM, Rangel-Moreno J, Randall TD, Hernady E, Finkelstein JN, Williams JP. Neonatal irradiation sensitizes mice to delayed pulmonary challenge. Radiat Res. 2013: 179(4):475-84.

Kalash R, Epperly MW, Goff J, Dixon T, Sprachman MM, Zhang X, Shields D, Cao S, Franicola D, Wipf P, Berhane H, Wang H, Au J, Greenberger JS. Amelioration of radiation-induced pulmonary fibrosis by a water-soluble bifunctional sulfoxide radiation mitigator (MMS350). Radiat Res. 2013: 180(5):474-90.

Kurland IJ, Accili D, Burant C, Fischer SM, Kahn BB, Newgard CB, Ramagiri S, Ronnett GV, Ryals JA, Sanders M, Shambaugh J, Shockcor J, Gross SS. Application of combined omics platforms to accelerate biomedical discovery in diabesity. Ann N Y Acad Sci. 2013: 1287:1-16.

Lazo JS, Sharlow ER, Epperly MW, Lira A, Leimgruber S, Skoda EM, Wipf P, Greenberger JS. Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death. J Pharmacol Exp Ther. 2013: 347(3):669-80.

Lenarczyk M, Lam V, Jensen E, Fish BL, Su J, Koprowski S, Komorowski RA, Harmann L, Migrino RQ, Li XA, Hopewell JW, Moulder JE, Baker JE. Cardiac injury after 10 gy total body irradiation: indirect role of effects on abdominal organs. Radiat Res. 2013: 180(3):247-58.

Levêque P, Desmet C, Dos Santos-Goncalvez AM, Beun S, Leprince JG, Leloup G, Gallez B. Influence of free radicals signal from dental resins on the radio-induced signal in teeth in EPR retrospective dosimetry. PLoS One. 2013: 8(5):e62225.

Landes RD, Lensing SY, Kodell RL, Hauer-Jensen M. Practical advice on calculating confidence intervals for radioprotection effects and reducing animal numbers in radiation countermeasure experiments. Radiat Res. 2013: 180(6):567-74.

Li P, Du F, Yuelling LW, Lin T, Muradimova RE, Tricarico R, Wang J, Enikolopov G, Bellacosa A, Wechsler-Reya RJ, Yang ZJ. A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. Nat Neurosci. 2013: 16(12):1737-44.

Manna SK, Krausz KW, Bonzo JA, Idle JR, Gonzalez FJ. Metabolomics reveals aging-associated attenuation of noninvasive radiation biomarkers in mice: potential role of polyamine catabolism and incoherent DNA damage-repair. J Proteome Res. 2013: 12(5):2269-81.

Manning CM, Johnston CJ, Reed CK, Lawrence BP, Williams JP, Finkelstein JN. Lung irradiation increases mortality after influenza A virus challenge occurring late after exposure. Int J Radiat Oncol Biol Phys. 2013: 86(1):128-35.

Martin NT, Nakamura K, Davies R, Nahas SA, Brown C, Tunuguntla R, Gatti RA, Hu H. ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response. PLoS Genet. 2013: 9(5):e1003505.

Palmer JL, Deburghgraeve CR, Bird MD, Hauer-Jensen M, Chen MM, Yong S, Kovacs EJ. Combined radiation and burn injury results in exaggerated early pulmonary inflammation. Radiat Res. 2013: 180(3):276-83.

Paul S, Smilenov LB, Amundson SA Widespread decreased expression of immune function genes in human peripheral blood following radiation exposure. Radiat Res. 2013: 180(6):575-83.

Ponnaiya B, Amundson SA, Ghandhi SA, Smilenov LB, Geard CR, Buonanno M, Brenner DJ. Single-cell responses to ionizing radiation. Radiat Environ Biophys. 2013: 52(4):523-30.

Shuryak I, Smilenov LB, Kleiman NJ, Brenner DJ. Potential reduction of contralateral second breast-cancer risks by prophylactic mammary irradiation: validation in a breast-cancer-prone mouse model. PLoS One. 2013: 8(12):e85795.

Slight SR, Monin L, Gopal R, Avery L, Davis M, Cleveland H, Oury TD, Rangel-Moreno J, Khader SA. IL-10 restrains IL-17 to limit lung pathology characteristics following pulmonary infection with Francisella tularensis live vaccine strain. Am J Pathol. 2013: 183(5):1397-404.

Sprung CN, Ivashkevich A, Forrester HB, Redon CE, Georgakilas A, Martin OA. Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects. Cancer Lett. 2013: pii: S0304-3835(13)00661-7.

Tyurina YY, Winnica DE, Kapralova VI, Kapralov AA, Tyurin VA, Kagan VE. LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: implications for mitochondrial dysfunction associated with Parkinson's disease. Mol Nutr Food Res. 2013: 57(8):1410-22.

Wen H, Miao EA, Ting JP. Mechanisms of NOD-like receptor-associated inflammasome activation.  Immunity. 2013: 39(3):432-41.

Xu Y, Turner HC, Garty G, Brenner D. A Rapid, Quantitative Method to Characterize The Human Lymphocyte Concentration for Automated High-Throughput Radiation Biodosimetry. Biomed Eng Res. 2013: 2(1):16-19.

Yanamala N, Hatfield MK, Farcas MT, Schwegler-Berry D, Hummer JA, Shurin MR, Birch ME, Gutkin DW, Kisin E, Kagan VE, Bugarski AD, Shvedova AA. Biodiesel versus diesel exposure: enhanced pulmonary inflammation, oxidative stress, and differential morphological changes in the mouse lung.Toxicol Appl Pharmacol. 2013: 272(2):373-83.

Zachman DK, Leon RP, Das P, Goldman DC, Hamlin KL, Guha C, Fleming WH. Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury. Stem Cell Res. 2013: 11(3):1013-21.

Hacke K, Treger J, Bogan B, Schiestl R, Kasahara N. Genetic modification of mouse bone marrow by lentiviral vector-mediated delivery of hypoxanthine-Guanine phosphoribosyltransferase short hairpin RNA confers chemoprotection against 6-thioguanine cytotoxicity. Transplant Proc. 2013: 45(5), 2040-4.

Manning, C, Johnston C, Hernady E, Miller J, Reed C, Lawrence P, Williams J, Finkelstein J. Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein. Radiat Res. 2013: 179(6), 617-29.

Laurent G, German N, Saha A, de Boer V, Davies M, Koves T, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch S, Sharpe A, Kurland I, Steegborn C, Gygi S, Muoio D, Ruderman, Neil B; Haigis, Marcia C. SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase' Mol Cell (2013): 50(5), 686-98.

Frantz MC, Skoda E, Sacher J, Epperly M, Goff J, Greenberger J, Wipf P. Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria. Org Biomol Chem. 2013: 11(25), 4147-53.

Arachchige A, Samarabandu J, Knoll J, Rogan P. Intensity integrated Laplacian-based thickness measurement for detecting human metaphase chromosome centromere location. IEEE Trans Biomed Eng. 2013: 60(7), 2005-13.

Goff J, Shields D, Wang H, Skoda E, Sprachman M, Wipf P, Garapati V, Atkinson J, London B, Lazo J, Kagan V, Epperly M, Greenberger J. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013.

Tyurina Y, Winnica D, Kapralova V, Kapralov A, Tyurin V, Kagan V. LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: Implications for mitochondrial dysfunction associated with Parkinson's disease. Mol Nutr Food Res. 2013: 57(8), 1410-22.

Epperly M, Chaillet J, Kalash R, Shaffer B, Goff J, Franicola D, Zhang X, Dixon T, Houghton F, Wang H, Berhane H, Romero C, Kim J, Greenberger J. Conditional Radioresistance of tet-Inducible Manganese Superoxide Dismutase Bone Marrow Stromal Cell Lines. Radiat Res. 2013: 180(2), 189-204.

Coy, Stephen L; Krylov, Evgeny V; Nazarov, Erkinjon G; Fornace Jr, Albert J; Kidd, Richard D. Differential mobility spectrometry with nanospray ion source as a compact detector for small organics and inorganicsInt J Ion Mobil Spectrom. 2013: 16(3), 217-227.

Forrester HB, Temple-Smith P; Ham S, de Kretser D, Southwick G, Sprung CN. Genome-wide analysis using exon arrays demonstrates an important role for expression of extra-cellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease. PLoS One. 2013: 8(3), e59056.

Pinto VH, Carvalhoda-Silva D, Santos, JL, Weitner T, Fonseca MG, Yoshida MI, Idemori YM, Batinic-Haberle I, Reboucas JS. Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+). J Pharm Biomed Anal. 2013: 73, 29-34.

Doan PL, Himburg, HA, Helms K, Russell JL, Fixsen E, Quarmyne M, Harris JR, Deoliviera D, Sullivan JM, Chao NJ, Kirsch DG, Chute JP. Epidermal growth factor regulates hematopoietic regeneration after radiation injury. Nat Med. 2013: 19(3), 295-304.

Chen, Benny J; Jiao, Yiqun; Zhang, Ping; Sun, Albert Y; Pitt, Geoffrey S; Deoliveira, Divino; Drago, Nicholas; Ye, Tong; Liu, Chen; Chao, Nelson J. Long-term in vivo imaging of multiple organs at the single cell level. PLoS One. 2013: 8(1), e52087.

Zheng J, Garg S, Wang J, Loose DS, Hauer-Jensen M. Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestine. PLoS One. 2013: 8(1), e53711.

Lynch HE, Sempowski GD. Molecular measurement of T cell receptor excision circles. Methods Mol Biol. 2013: 979, 147-59.

Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting, JP. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. PLoS One. 2013: 8(4), e60842.

Tovmasyan A, Weitner T, Sheng H, Lu M, Rajic Z, Warner DS, Spasojevic I, Reboucas JS, Benov L, Batinic-Haberle I. Differential Coordination Demands in Fe versus Mn Water-Soluble Cationic Metalloporphyrins Translate into Remarkably Different Aqueous Redox Chemistry and Biology. Inorg Chem. 2013: 52(10), 5677-91.

Pothlichet J, Meunier, I, Davis, BK, Ting, JP, Skamene E, von Messling V, Vidal SM. Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells. PLoS Pathog. 2013: 9(4), e1003256.

Miao W, Xufeng R, Park M-R, Gu H, Hu L, Kang JW, Ma S, Liang PH, Li Y, Cheng H, Yu H, Epperly M, Greenberger J, Cheng T. Hematopoietic stem cell regeneration enhanced by ectopic expression of ROS-detoxifying enzymes in transplant mice. Mol Ther. 2013: 21(2), 423-32.

Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. J Clin Invest. 2013: 123(2), 712-26.

Johnston CJ, Manning CM, Rangel-Moreno J, Randall TD, Hernady E, Finkelstein JN, Williams JP. Neonatal irradiation sensitizes mice to delayed pulmonary challenge. Radiat Res. 2013: 179(4), 475-84.

Beyoglu D, Imbeaud S, Maurhofer O, Bioulac-Sage P, Zucman-Rossi J, Dufour J, Idle J. Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classificationHepatology. (2013).

Zhou D, Deoliveira D, Kang Y, Choi S, Li Z, Chao N, Chen B. Insulin-like growth factor 1 mitigates hematopoietic toxicity after lethal total body irradiationInt J Radiat Oncol Biol Phys. 2013: 85(4), 1141-8.

Doan P, Russel JL, Himburg H, Helms K, Harris JR, Lucas J et alTie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injuryStem Cells. 2013: 31(2), 327-37.

Racioppi L. CaMKK2: a novel target for shaping the androgen-regulated tumor ecosystemTrends Mol Med. 2013: 19(2), 83-8.

Tovmasyan A, Sheng H, Weitner T, Arulpragasam A, Lu M, Warner D et alDesign, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulatorsMed Princ Pract. 2013: 22(2), 103-30.

Zheng J, Garg S, Wang J, Loose D, Hauer-Jensen M. Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestinePLoS One. 2013: 8(1), e53711.

Lynch H, Sempowski G. Molecular measurement of T cell receptor excision circlesMethods Mol Biol. 2013: 979, 147-59.

Weitner T, Kos I, Sheng H, Tovmasyan A, Reboucas J, Fan P, Warner D et alComprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP(5+) and MnTnHex-2-PyP(5+)Free Radic Biol Med. 2013: 58, 73-80.

Zhou S, Nissao E, Jackson I, Leong W, Dancy L, Cuttitta F et alRadiation-induced lung injury is mitigated by blockade of gastrin-releasing peptideAm J Pathol. 2013: 182(4), 1248-54.

Gao X, Huang Y, Makhov M, Epperly M, Lu J, Grab S et alNanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriersMol Pharm. 2013: 10(1), 187-98.

Miao W, Xufeng R, Park M, Gu H, Hu L, Kang J et alHematopoietic stem cell regeneration enhanced by ectopic expression of ROS-detoxifying enzymes in transplant miceMol Ther. 2013: 21(2), 423-32.

Manning C, Johnston C, Reed C, Lawrence BP, Williams J, Finkelstein J. Lung irradiation increases mortality after influenza aýývirus challenge occurring late after exposureInt J Radiat Oncol Biol Phys. 2013: 86(1), 128-35.​

Xie M, Gorodetsky R,  Micevicz E, Mackenzie N, Gaberman E, Levdansky et al. Marrow-derived stromal cell delivery on fibrin microbeads can correct radiation-induced wound-healing deficits. J Invest Dermatol. 2013: 133(2), 553-61.

Ghosh S, Singh R, Chakraborty K,  Kulkarni S, Uppal A, Luo Y et al. Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model. Mol Biosyst. 2013: 9(4), 723-31.

Chen B, Jiao Y, Zhang P, Sun A, Pitt G, Deoliveira D et al. Long-term in vivo imaging of multiple organs at the single cell level. PLoS One. 2013: 8(1), e52087.

2012

Blecher K, Martinez LR, Tuckman-Vernon C, Nacharaju P, Schairer D, Chouake J, Friedman JM, Alfieri A, Guha C, Nosanchuk JD, Friedman AJ. Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine. 2012: 8(8):1364-71.

Hannan R, Zhang H, Wallecha A, Singh R, Liu L, Cohen P, Alfieri A, Rothman J, Guha C. Combined immunotherapy with Listeria monocytogenes-based PSA vaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer. Cancer Immunol Immunother. 2012: 61(12):2227-38.

Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol. 2012: 13(12):1155-61.

Sahler J, Woeller C, Spinelli S, Blumberg N, Phipps R. A novel method for overexpression of peroxisome proliferator-activated receptor-γ in megakaryocyte and platelet microparticles achieves transcellular signaling. J Thromb Haemost. 2012: 10(12):2563-72.

Swartz HM, Flood AB, Williams BB, Dong R, Swarts SG, He X, Grinberg O, Sidabras J, Demidenko E, Gui J, Gladstone DJ, Jarvis LA, Kmiec MM, Kobayashi K, Lesniewski PN, Marsh SD, Matthews TP, Nicolalde RJ, Pennington PM, Raynolds T, Salikhov I, Wilcox DE, Zaki BI. Electron paramagnetic resonance dosimetry for a large-scale radiation incident. Health Phys. 2012: 103(3):255-67.

Vaitheesvaran B, Yang L, Hartil K, Glaser S, Yazulla S, Bruce JE, Kurland IJ. Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation. PLoS One. 2012: 7(3):e33717.

Zhang H, Liu L, Yu D, Kandimalla ER, Sun HB, Agrawal S, Guha C. An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy. PLoS One. 2012: 7(5):e38111.

Schaue D, Kachikwu E, McBride W. Cytokines in radiobiological responses: a review. Radiat Res. 2012: 178(6), 505-23.

Chen Y, Wang H, Zhang J, Garty G, Simaan N, Yao L et al. Automated Recognition of Robotic Manipulation Failures in High-throughput Biodosimetry Tool. Expert Syst Appl. 2012: 39(10), 9602-9611.

Johnson C, PattersonA, Krausz K, Kalinich J, Tyburski J, Kang D et al. Radiation metabolomics. 5. Identification of urinary biomarkers of ionizing radiation exposure in nonhuman primates by mass spectrometry-based metabolomics. Radiat Res. 2012: 178(4), 328-40.

Fahrner R,  Beyoglu D, Beldi G, Idle J. Metabolomic markers for intestinal ischemia in a mouse model. J Surg Res. 2012: 178(2), 879-87.

Biju P, Garg S,Wang W, Choudhry M, Kovacs E, Fink L et al. Procalcitonin as a predictive biomarker for total body irradiation-induced bacterial load and lethality in mice. Shock 2012: 38(2), 170-6.

Zhou D, Deoliveira D, Kang Y, Choi S, Li Z, Chao N et al. Insulin-Like Growth Factor 1 Mitigates Hematopoietic Toxicity After Lethal Total Body Irradiation. Int J Radiat Oncol Biol Phys. 2012: 85(4), 1141-8.

Mendoza A, Neely C, Charles A, Kartchner L, Brickey W, Khoury A et al. Radiation combined with thermal injury induces immature myeloid cells. Shock. 2012: 38(5), 532-42.

Racioppi L, Means A. Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology. J Biol Chem. 2012: 287(38), 31658-65.

Himburg H, Harris J, Ito T, Daher P, Russell J, Quarmyne M et al. Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. Cell Rep. 2012: 2(4), 964-75.

Zellefrow C, Sharlow E, Epperly M, Reese C, Shun T, Lira A et al. Identification of druggable targets for radiation mitigation using a small interfering RNA screening assay. Radiat Res. 2012: 178(3), 150-9.

Xun Z, Rivera-Sanchez S, Ayala-Pena S, Lim J, Budworth H, Skoda E et al. Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease. Cell Rep. 2012: 2(5), 1137-42.

Swartz H, Flood A, Williams B, Dong R, Swarts S, He X et al. Electron paramagnetic resonance dosimetry for a large-scale radiation incident. Health Phys. 2012: 103(3), 255-67.

Cummings R, Gerber S, Judge J, Ryan J, Pentland A, Lord E. Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism. J Immunol. 2012: 189(9), 4247-57.

Peslak S, Wenger J, Bemis J, Kingsley P, Koniski A, McGrath K, Palis J. EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress. Blood. 2012: 120(12), 2501-11.

Manning C, Johnston C, Reed C, Lawrence B, Williams J, Finkelstein J. Lung Irradiation Increases Mortality After Influenza A Virus Challenge Occurring Late After Exposure. Int J Radiat Oncol Biol Phys. 2012: 1-8.

Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58(2), 169-77.

Beyoglu D, Smith R, Idle JR. Dog bites man or man bites dog? The enigma of the amino acid conjugations.Biochem Pharmacol .2012;83(10),1331-9.

Chen Y, Wang H, Zhang J, Garty G, Simaan N, Yao YL, Brenner DJ. Automated Recognition of Robotic Manipulation Failures in High-throughput Biodosimetry Tool. Expert Syst Appl . 2012;39(10), 9602-9611.

Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha , Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP-Y. MyD88 provides a protective role in long-term radiation-induced lung injury. Int J Radiat Biol. 2012;88(4), 335-47.

Landes, RD; Lensing, SY; Kodell, RL; Hauer-Jensen, M. Statistical analysis of survival data from radiation countermeasure experiments. Radiat Res. 2012; 177(5), 546-54.

Zhang Y, Zhang, X, Rabbani, ZN, Jackson IL, Vujaskovic, Z. Oxidative stress mediates radiation lung injury by inducing apoptosis. Int J Radiat Oncol Biol Phys. 2012; 83(2), 740-8.

Allen IC, Wilson, JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RT, Davis BK, Uronis JM, Herfarth HH, Jobin, C, Rogers, AB, Ting JP-Y. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-ýýB signaling. Immunity. 2012; 36(5), 742-54.

Kapralov AA, Feng WH, Amoscato AA, Yanamala N, Balasubramanian K, Winnica DE. et al. Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration ACS Nano. 2012; 6(5), 4147-56.

Saha, Subhrajit; Bhanja, Payel; Liu, Laibin; Alfieri, Alan A; Yu, Dong; Kandimalla, Ekambar R; Agrawal, Sudhir; Guha, Chandan . TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome. PLoS One. 2012;7(1):e29357.

Allen, Irving C; Lich, John D; Arthur, Janelle C; Jania, Corey M; Roberts, Reid A; Callaway, Justin B; Tilley, Stephen L; Ting, Jenny P-Y. Characterization of NLRP12 during the development of allergic airway disease in mice. PLoS One. 2012;7(1):e30612.

Nowak, Grazyna; Bakajsova, Diana; Hayes, Corey; Hauer-Jensen, Martin; Compadre, Cesar M. γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther. 2012 Feb;340(2):330-8.

Berbee, Maaike; Hauer-Jensen, Martin. Novel drugs to ameliorate gastrointestinal normal tissue radiation toxicity in clinical practice: what is emerging from the laboratory? Curr Opin Support Palliat Care. 2012 Mar;6(1):54-9.

Allen, Irving C; Jania, Corey M; Wilson, Justin E; Tekeppe, Erin M; Hua, Xiaoyang; Brickey, Willie J; Kwan, Mildred; Koller, Beverly H; Tilley, Stephen L; Ting, Jenny P-Y. Analysis of NLRP3 in the development of allergic airway disease in mice. J Immunol. 2012 Mar 15;188(6):2884-93.

Hein, Amy M; O'Banion, M Kerry. Neuroinflammation and cognitive dysfunction in chronic disease and aging. J Neuroimmune Pharmacol. 2012 Mar;7(1):3-6.

Hacke, Katrin; Szakmary, Akos; Cuddihy, Andrew R; Rozengurt, Nora; Lemp, Nathan A; Aubrecht, Jiri; Lawson, Gregory W; Rao, Nagesh P; Crooks, Gay M; Schiestl, Robert H; Kasahara, Noriyuki. Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol. 2012 Jan;40(1):3-13.e3.

Gatti, Richard A. SMRT compounds correct nonsense mutations in primary immunodeficiency and other genetic models. Ann N Y Acad Sci. 2012 Feb;1250:33-40.

Davies, Robert C; Pettijohn, Kelly; Fike, Francesca; Wang, Jiexi; Nahas, Shareef A; Tunuguntla, Rashmi; Hu, Hailiang; Gatti, Richard A; McCurdy, Deborah. Defective DNA double-strand break repair in pediatric systemic lupus erythematosus. Arthritis Rheum. 2012 Feb;64(2):568-78.

2011

Kim, Kwanghee; Damoiseaux, Robert; Norris, Andrew J; Rivina, Leena; Bradley, Kenneth; Jung, Michael E; Gatti, Richard A; Schiestl, Robert H; McBride, William H. High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol. 2011 Aug;87(8):839-45.

Williams, Jacqueline P; McBride, William H. After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS). Int J Radiat Biol. 2011 Aug;87(8):851-68.

Garty G, Chen Y, Turner HC, Zhang J, Lyulko OV, Bertucci A, Xu Y, Wang H, Simaan N, Randers-Pehrson G, Lawrence Yao Y, Brenner DJ. The RABiT: a rapid automated biodosimetry tool for radiological triage. II. Technological developments. Int J Radiat Biol. 2011 Aug;87(8):776-90.

Garty, Guy; Karam, Andrew; Brenner, David J. Infrastructure to support ultra high throughput biodosimetry screening after a radiological event. Int J Radiat Biol. 2011 Aug;87(8):754-65.

Yang, Li; Vaitheesvaran, Bhavapriya; Hartil, Kirsten; Robinson, Alan J; Hoopmann, Michael R; Eng, Jimmy K; Kurland, Irwin J; Bruce, James E. The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching. J Proteome Res. 2011 Sep 2;10(9):4134-49.

Paul, Sunirmal; Amundson, Sally A. Gene expression signatures of radiation exposure in peripheral white blood cells of smokers and non-smokers. Int J Radiat Biol. 2011 Aug;87(8):791-801.

Coy, Stephen L; Cheema, Amrita K; Tyburski, John B; Laiakis, Evagelia C; Collins, Sean P; Fornace Jr, Albert. Radiation metabolomics and its potential in biodosimetry. Int J Radiat Biol. 2011 Aug;87(8):802-23.

Patterson, Andrew D; Maurhofer, Olivier; Beyoglu, Diren; Lanz, Christian; Krausz, Kristopher W; Pabst, Thomas; Gonzalez, Frank J; Dufour, Jean-Francois; Idle, Jeffrey R. Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling. Cancer Res. 2011 Nov 1;71(21):6590-600.

Williams, Paul D; Owens, Charles R; Dziegielewski, Jaroslaw; Moskaluk, Christopher A; Read, Paul W; Larner, James M; Story, Michael D; Brock, William A; Amundson, Sally A; Lee, Jae K; Theodorescu, Dan. Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy. Neoplasia. 2011 Dec;13(12):1122-31.

Ross, Joel R; Case, Cullen; Confer, Dennis; Weisdorf, Daniel J; Weinstock, David; Krawisz, Robert; Chute, John; Wilhauk, Julie; Navarro, Willis; Hartzman, Robert; Norman Coleman, C; Hatchett, Richard; Chao, Nelson. Radiation injury treatment network (RITN): healthcare professionals preparing for a mass casualty radiological or nuclear incident. Int J Radiat Biol. 2011 Aug;87(8):748-53.

Klymenko, Sergiy V; Belyi, David A; Ross, Joel R; Owzar, Kouros; Jiang, Chen; Li, Zhiguo; N Minchenko, Janna; N Kovalenko, Aleksandr; Bebeshko, Volodymyr G; J Chao, Nelson. Hematopoietic cell infusion for the treatment of nuclear disaster victims: new data from the Chernobyl accident. Int J Radiat Biol. 2011 Aug;87(8):846-50.

Deoliveira, Divino; Jiao, Yiqun; Ross, Joel R; Corbin, Kayla; Xiao, Qizhen; Toncheva, Greta; Anderson-Evans, Colin; Yoshizumi, Terry T; Chen, Benny J; Chao, Nelson J. An ear punch model for studying the effect of radiation on wound healing. Int J Radiat Biol. 2011 Aug;87(8):869-77.

Batinic-Haberle, Ines; Rajic, Zrinka; Tovmasyan, Artak; Reboucas, Julio S; Ye, Xiaodong; Leong, Kam W; Dewhirst, Mark W; Vujaskovic, Zeljko; Benov, Ludmil; Spasojevic, Ivan. Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. Free Radic Biol Med. 2011 Sep 1;51(5):1035-53.

Jia, Dan; Gaddy, Dana; Suva, Larry J; Corry, Peter M. Rapid loss of bone mass and strength in mice after abdominal irradiation. Radiat Res. 2011 Nov;176(5):624-35.

Williams, Benjamin B; Dong, Ruhong; Nicolalde, Roberto J; Matthews, Thomas P; Gladstone, David J; Demidenko, Eugene; Zaki, Bassem I; Salikhov, Ildar K; Lesniewski, Piotr N; Swartz, Harold M. Physically-based biodosimetry using in vivo EPR of teeth in patients undergoing total body irradiation. Int J Radiat Biol. 2011 Aug;87(8):766-75.

He, Xiaoming; Gui, Jiang; Matthews, Thomas P; Williams, Benjamin B; Swarts, Steven G; Grinberg, Oleg; Sidabras, Jason; Wilcox, Dean E; Swartz, Harold M. Advances towards using finger/toenail dosimetry to triage a large population after potential exposure to ionizing radiation. Radiat Meas. 2011 Sep;46(9):882-887.

Flood, Ann Barry; Nicolalde, Roberto J; Demidenko, Eugene; Williams, Benjamin B; Shapiro, Alla; Wiley Jr, Albert L; Swartz, Harold M. A Framework for Comparative Evaluation of Dosimetric Methods to Triage a Large Population Following a Radiological Event. Radiat Meas. 2011 Sep 1;46(9):916-922.

Williams, Benjamin B; Dong, Ruhong; Flood, Ann Barry; Grinberg, Oleg; Kmiec, Maciej; Lesniewski, Piotr N; Matthews, Thomas P; Nicolalde, Roberto J; Raynolds, Tim; Salikhov, Ildar K; Swartz, Harold M. A Deployable In Vivo EPR Tooth Dosimeter for Triage After a Radiation Event Involving Large Populations. Radiat Meas. 2011 Sep 1;46(9):772-777.

Jiang, Jianfei; Maeda, Akihiro; Ji, Jing; Baty, Catherine J; Watkins, Simon C; Greenberger, Joel S; Kagan, Valerian E. Are mitochondrial reactive oxygen species required for autophagy? Biochem Biophys Res Commun. 2011 Aug 19;412(1):55-60.

Tyurina, Yulia Y; Kisin, Elena R; Murray, Ashley; Tyurin, Vladimir A; Kapralova, Valentina I; Sparvero, Louis J; Amoscato, Andrew A; Samhan-Arias, Alejandro K; Swedin, Linda; Lahesmaa, Riitta; Fadeel, Bengt; Shvedova, Anna A; Kagan, Valerian E. Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubes. ACS Nano. 2011 Sep 27;5(9):7342-53.

Belikova, Natalia A; Glumac, Ashley L; Kapralova, Valentyna; Cheikhi, Amin; Tyurina, Yulia Y; Vagni, Vincent A; Kochanek, Patrick M; Kagan, Valerian E; Bayir, Hulya. A high-throughput screening assay of ascorbate in brain samples. J Neurosci Methods. 2011 Sep 30;201(1):185-90.

Meireles, Lidio; Gur, Mert; Bakan, Ahmet; Bahar, Ivet. Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins. Protein Sci. 2011 Oct;20(10):1645-58. doi: 10.1002/pro.711.

Kim, Hyun; Bernard, Mark E; Epperly, Michael W; Shen, Hongmei; Amoscato, Andrew; Dixon, Tracy M; Doemling, Alexander S; Li, Song; Gao, Xiang; Wipf, Peter; Wang, Hong; Zhang, Xichen; Kagan, Valerian E; Greenberger, Joel S. Amelioration of radiation esophagitis by orally administered p53/Mdm2/Mdm4 inhibitor (BEB55) or GS-nitroxide. In Vivo. 2011 Nov-Dec;25(6):841-8.

Stoyanovsky, Detcho A; Huang, Zhentai; Jiang, Jianfei; Belikova, Natalia A; Tyurin, Vladimir; Epperly, Michael W; Greenberger, Joel S; Bayir, Hulya; Kagan, Valerian E. A manganese-porphyrin complex decomposes H(2)O(2), inhibits apoptosis, and acts as a radiation mitigator in vivo. ACS Med Chem Lett. 2011 Nov 10;2(11):814-817.

Peslak, Scott A; Wenger, Jesse; Bemis, Jeffrey C; Kingsley, Paul D; Frame, Jenna M; Koniski, Anne D; Chen, Yuhchyau; Williams, Jacqueline P; McGrath, Kathleen E; Dertinger, Stephen D; Palis, James. Sublethal radiation injury uncovers a functional transition during erythroid maturation. Exp Hematol. 2011 Apr;39(4):434-45.

Johnston, Carl J; Manning, Casey; Hernady, Eric; Reed, Christina; Thurston, Sally W; Finkelstein, Jacob N; Williams, Jacqueline P. Effect of total body irradiation on late lung effects: hidden dangers. Int J Radiat Biol. 2011 Aug;87(8):902-13.

Williams, Jacqueline P; McBride, William H. After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS). Int J Radiat Biol. 2011 Aug;87(8):851-68.

Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski JD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. Sublethal radiation injury uncovers a functional transition during erythroid maturation.  Exp Hematol. 2011;39(4):434-45.

Kuzin I, Sun H, Moshkani S, Feng C, Mantalaris A, Wu JHD, Bottaro A. Long-term immunologically competent human peripheral lymphoid tissue cultures in a 3D bioreactor.  Biotechnol Bioeng. 2011;108(6):1430-40.

Zhang M, Swarts SG, Yin L, Liu C, Tian Y, Cao Y, Swarts M, Yang S, Zhang SB, Zhang K, Ju S, Olek DJ, Schwartz L, Keng PC, Howell R, Zhang L, Okunieff P. Antioxidant properties of quercetin.  Adv Exp Med Biol. 2011;701:283-9.

Swarts SG, Zhang M, Yin L, Liu C, Tian Y, Cao Y, Swarts M, Olek DJ, Schwartz L, Zhang L, Yang S, Zhang SB, Zhang K, Ju S, Vidyasagar S, Zhang L, Okunieff P.  Antioxidant properties of select radiation mitigators based on semicarbazone and pyrazole derivatives of curcumin.  Adv Exp Med Biol. 2011;701:291-7.

Zhang H, Maguire DJ, Zhang M, Zhang L, Okunieff P.  Elevated mitochondrial DNA copy number and POL-γ expression but decreased expression of TFAM in murine intestine following therapeutic dose irradiationAdv Exp Med Biol. 2011;701:201-6.

Cohen EP, Bruder ED, Cullinan WE, Ziegler D, Raff H.  Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the ratTransl Res. 2011;157(1):38-47.

Moulder JE, Cohen EP, Fish BL.  Captopril and losartan for mitigation of renal injury caused by single-dose total-body irradiationRadiat Res. 2011;175:29-36.

Jenrow KA, Liu J, Brown SL, Kolozsvary A, Lapanowski K, Kim JH.  Combined atorvastatin and ramipril mitigate radiation-induced impairment of dentate gyrus neurogenesisJ Neurooncol. 2011;101(3):449-56.

Clarkson R, Lindsay PE, Ansell S, Wilson G, Jelveh S, Hill RP, Jaffray DA.  Characterization of image quality and image-guidance performance of a preclinical microirradiatorMed Phys.  2011;38(2):845-56.

Dayger C, Villasana L, Pfankuch T, Davis M, Raber J.  Effects of the SARM ACP-105 on rotorod performance and cued fear conditioning in sham-irradiated and irradiated female miceBrain Res. 2011;1381:134-40.

Raff H, Bruder ED, Cullinan WE, Ziegler DR, Cohen EP.  Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and renin-aldosterone activity in the ratEndocrinology. 2011;152(4):1218-21.

Moulder JE, Fish BL, Cohen EP, Klein JP.  Re: Davis et al., Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiationExp Hematol. 2011;39(5):521-2, author reply 522-4.

Hu H, Gatti RA.  MicroRNAs: new players in the DNA damage responseJ Mol Cell Biol. 2011; 3(3):151-8.

Mielcarek M, Storb R, Georges GE, Golubev L, Nikitine A, Hwang B, Nash RA, Torok-Storb B.  Mesenchymal stromal cells fail to prevent acute graft-versus-host disease and graft rejection after dog leukocyte antigen-haploidentical bone marrow transplantationBiol Blood Marrow Transplant. 2011;17(2):214-25.

Pogosova-Agadjanyan EL, Fan W, Georges GE, Schwartz JL, Kepler CM, Lee H, Suchanek AL, Cronk MR, Brumbaugh A, Engel JH, Yukawa M, Zhao LP, Heimfeld S, Stirewalt DL.  Identification of radiation-induced expression changes in nonimmortalized human T cellsRadiat Res. 2011;175(2):172-84.

Ivey RG, Moore HD, Voytovich UJ, Thienes CP, Lorentzen TD, Pogosova-Agadjanyan EL, Frayo S, Izaguirre VK, Lundberg SJ, Hedin L, Badiozamani KR, Hoofnagle AN, Stirewalt DL, Wang P, Georges GE, Gopal AK, Paulovich AG.  Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISARadiat Res. 2011;175(3):266-81.

Lee WS, Suzuki Y, Graves SS, Iwata M, Venkataraman GM, Mielcarek M, Peterson LJ, Ikehara S, Torok-Storb B, Storb R.  Canine bone marrow-derived mesenchymal stromal cells suppress alloreactive lymphocyte proliferation in vitro but fail to enhance engraftment in canine bone marrow transplantationBiol Blood Marrow Transplant. 2011;17(4):465-75.

Graves SS, Stone DM, Loretz C, Peterson LJ, Lesnikova M, Hwang B, Georges GE, Nash R, Storb R.  Antagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantationTransplantation. 2011;91(8):833-40.

Shuryak, I, Sachs, R K, Brenner, D J.  A new view of radiation-induced cancerRadiat Prot Dosimetry. 2011;143(2-4):358-64.

Marino SA, Johnson GW, Schiff PB, Brenner DJ.  Modification of shirt buttons for retrospective radiation dosimetry after a radiological eventHealth Phys. 2011;100(5):542-7.

Johnson CH, Patterson AD, Krausz KW, Lanz C, Kang DW, Luecke H, Gonzalez FJ, Idle JR.  Radiation metabolomics. 4. UPLC-ESI-QTOFMS-Based metabolomics for urinary biomarker discovery in gamma-irradiated ratsRadiat Res. 2011;175(4):473-84.

Lanz C, Ledermann M, Slavik J, Idle JR.  The production and composition of rat sebum is unaffected by 3 Gy gamma radiationInt J Radiat Biol. 2011;87(4):360-71.

Templin T, Paul S, Amundson SA, Young EF, Barker CA, Wolden SL, Smilenov LB. Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patientsInt J Radiat Oncol Biol Phys. 2011;80(2):549-57.

Palmer JL, Deburghgraeve CR, Bird MD, Hauer-Jensen M, Kovacs EJ.  Development of a combined radiation and burn injury modelJ Burn Care Res. 2011;32(2):317-23.

Jackson IL, Vujaskovic Z, Down JD.  A further comparison of pathologies after thoracic irradiation among different mouse strains: finding the best preclinical model for evaluating therapies directed against radiation-induced lung damageRadiat Res. 2011;175(4):510-18.

Tovmasyan AG, Rajic Z, Spasojevic I, Reboucas JS, Chen X, Salvemini D, Sheng H, Warner DS, Benov L, Batinic-Haberle I.  Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrinsDalton Trans. 2011;40(16):4111-21.

Epperly MW, Smith T, Zhang X, Goff JP, Franicola D, Greenberger B, Komanduri P, Wang H, Greenberger JS.  Modulation of in utero total body irradiation induced newborn mouse growth retardation by maternal manganese superoxide dismutase-plasmid liposome (MnSOD-PL) gene therapyGene Ther. 2011;18(6):579-83.

Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE.  Oxidative lipidomics of ýý-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidationRadiat Res. 2011;175(5):610-21.

Frantz M-C, Pierce JG, Pierce JM, Kangying L, Qingwei W, Johnson M, Wipf P.  Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogsOrg Lett. 2011;13(9):2318-21.

Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J.  Sublethal radiation injury uncovers a functional transition during erythroid maturationExp Hematol. 2011;39(4):434-45.

Lv H, Palacios G, Hartil K, Kurland IJ.  Advantages of tandem LC-MS for the rapid assessment of tissue-specific metabolic complexity using a pentafluorophenylpropyl stationary phase.  J Proteome Res. 2011;10(4):2104-12.

Paul S, Barker CA, Turner HC, McLane A, Wolden SL, Amundson SA. Prediction of in vivo radiation dose status in radiotherapy patients using ex vivo and in vivo gene expression signatures. Radiat Res. 2011 Mar;175(3):257-65. Epub 2011 Jan 10.

Turner HC, Brenner DJ, Chen Y, Bertucci A, Zhang J, Wang H, Lyulko OV, Xu Y, Shuryak I, Schaefer J, Simaan N, Randers-Pehrson G, Yao YL, Amundson SA, Garty G. Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects. Radiat Res. 2011 Mar;175(3):282-90. Epub 2010 Dec 28.

Berbée M, Fu Q, Garg S, Kulkarni S, Kumar KS, Hauer-Jensen M. Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res. 2011 Mar;175(3):297-306. Epub 2010 Dec 28.

Amundson SA, Smilenov LB. Integration of biological knowledge and gene expression data for biomarker selection: FN1 as a potential predictor of radiation resistance in head and neck cancer. Cancer Biol Ther. 2011 Jan 12;10(12):1252-5. Epub 2010 Dec 15.

Ghandhi SA, Sinha A, Markatou M, Amundson SA. Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering. BMC Genomics. 2011 Jan 4;12:2.

Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Cutting edge: NLRC5-dependent activation of the inflammasome. J Immunol. 2011 Feb 1;186(3):1333-7. Epub 2010 Dec 29.

Rugo RE, Mutamba JT, Mohan KN, Yee T, Chaillet JR, Greenberger JS, Engelward BP. Methyltransferases mediate cell memory of a genotoxic insult. Oncogene. 2011 Feb 10;30(6):751-6. Epub 2010 Nov 8.

Berbee M, Fu Q, Boerma M, Pathak R, Zhou D, Kumar KS, Hauer-Jensen M. Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin. Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):884-91. Epub 2010 Oct 13.

 

2010

Shingrani R, Krenz G, Molthen R. Automation process for morphometric analysis of volumetric CT data from pulmonary vasculature in rats. Comput Methods Programs Biomed. 2010 Jan;97(1):62-77. Epub 2009 Aug 26.

Johnston CJ, Hernady E, Reed C, Thurston SW, Finkelstein JN, Williams JP. Early alterations in cytokine expression in adult compared to developing lung in mice after radiation exposure. Radiat Res. 2010 Apr;173(4):522-35.

Calveley VL, Jelveh S, Langan A, Mahmood J, Yeung IW, Van Dyk J, Hill RP. Genistein can mitigate the effect of radiation on rat lung tissue. Radiat Res. 2010 May;173(5):602-11.

Zhang L, Zhang M, Yang S, Cao Y, Bingrong Zhang S, Yin L, Tian Y, Ma Y, Zhang A, Okunieff P, Zhang L. A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma. Br J Radiol. 2010 Aug;83(992):694-701.

Sun H, Tsai Y, Nowak I, Dertinger SD, Wu JH, Chen Y. Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture. Mutat Res. 2011 Jan 10;718(1-2):38-43. Epub 2010 Nov 4.

Cohen EP, Pais P, Moulder JE. Chronic kidney disease after hematopoietic stem cell transplantation. Semin Nephrol. 2010 Nov;30(6):627-34.

Cohen EP, Fish BL, Moulder JE. Mitigation of radiation injuries via suppression of the renin-angiotensin system: emphasis on radiation nephropathy. Curr Drug Targets. 2010 Nov;11(11):1423-9.

Bhogal N, Kaspler P, Jalali F, Hyrien O, Chen R, Hill RP, Bristow RG. Late residual gamma-H2AX foci in murine skin are dose responsive and predict radiosensitivity in vivo. Radiat Res. 2010 Jan;173(1):1-9.

Shingrani R, Krenz G, Molthen R.
Automation process for morphometric analysis of volumetric CT data from pulmonary vasculature in rats. Comput Methods Programs Biomed. 2010 Jan;97(1):62-77. Epub 2009 Aug 26.

Jenrow KA, Brown SL, Liu J, Kolozsvary A, Lapanowski K, Kim JH. Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus. Radiat Oncol. 2010 Feb 1;5:6.

Williams BB, Dong R, Kmiec M, Burke G, Demidenko E, Gladstone D, Nicolalde RJ, Sucheta A, Lesniewski P, Swartz HM. Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Phys. 2010 Feb;98(2):327-38.

Wilcox DE, He X, Gui J, Ruuge AE, Li H, Williams BB, Swartz HM. Dosimetry based on EPR spectral analysis of fingernail clippings. Health Phys. 2010 Feb;98(2):309-17.

Black PJ, Swarts SG. Ex vivo analysis of irradiated fingernails: chemical yields and properties of radiation-induced and mechanically-induced radicals. Health Phys. 2010 Feb;98(2):301-8.

Rea ME, Gougelet RM, Nicolalde RJ, Geiling JA, Swartz HM. Proposed triage categories for large-scale radiation incidents using high-accuracy biodosimetry methods. Health Phys. 2010 Feb;98(2):136-44.

Chen Y, Tsai Y, Nowak I, Wang N, Hyrien O, Wilkins R, Ferrarotto C, Sun H, Dertinger SD. Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model. Health Phys. 2010 Feb;98(2):218-27.

Gougelet RM, Rea ME, Nicolalde RJ, Geiling JA, Swartz HM. The view from the trenches: part 1-emergency medical response plans and the need for EPR screening. Health Phys. 2010 Feb;98(2):118-27.

Nicolalde RJ, Gougelet RM, Rea M, Williams BB, Dong R, Kmiec MM, Lesniewski PN, Swartz HM. The view from the trenches: part 2-technical considerations for EPR screening. Health Phys. 2010 Feb;98(2):128-35.

Pollock JD, Williams BB, Sidabras JW, Grinberg O, Salikhov I, Lesniewski P, Kmiec M, Swartz HM. Surface loop resonator design for in vivo EPR tooth dosimetry using finite element analysis. Health Phys. 2010 Feb;98(2):339-44.

Prasanna PG, Blakely WF, Bertho JM, Chute JP, Cohen EP, Goans RE, Grace MB, Lillis-Hearne PK, Lloyd DC, Lutgens LC, Meineke V, Ossetrova NI, Romanyukha A, Saba JD, Weisdorf DJ, Wojcik A, Yukihara EG, Pellmar TC. Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop. Radiat Res. 2010 Feb;173(2):245-53.

Bentzen SM, Parliament M, Deasy JO, Dicker A, Curran WJ, Williams JP, Rosenstein BS. Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S145-50.

Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, Macvittie TJ, Mason KA, Medhora MM, Moulder JE, Okunieff P, Otterson MF, Robbins ME, Smathers JB, McBride WH. Animal models for medical countermeasures to radiation exposure. Radiat Res. 2010 Apr;173(4):557-78.

Johnston CJ, Hernady E, Reed C, Thurston SW, Finkelstein JN, Williams JP. Early alterations in cytokine expression in adult compared to developing lung in mice after radiation exposure. Radiat Res. 2010 Apr;173(4):522-35.

Szabo S, Ghosh SN, Fish BL, Bodiga S, Tomic R, Kumar G, Morrow NV, Moulder JE, Jacobs ER, Medhora M. Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic x radiation in rats. Radiat Res. 2010 Apr;173(4):545-56.

Brown SL, Kolozsvary A, Liu J, Jenrow KA, Ryu S, Kim JH. Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality. Radiat Res. 2010 Apr;173(4):462-8.

Zhang L, Sun W, Wang J, Zhang M, Yang S, Tian Y, Vidyasagar S, Peña LA, Zhang K, Cao Y, Yin L, Wang W, Zhang L, Schaefer KL, Saubermann LJ, Swarts SG, Fenton BM, Keng PC, Okunieff P. Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation. Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):261-8.

Calveley VL, Jelveh S, Langan A, Mahmood J, Yeung IW, Van Dyk J, Hill RP. Genistein can mitigate the effect of radiation on rat lung tissue. Radiat Res. 2010 May;173(5):602-11.

Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF. Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B. Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77. Epub 2010 Mar 18.

Vorotnikova E, Rosenthal RA, Tries M, Doctrow SR, Braunhut SJ. Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation. Radiat Res. 2010 Jun;173(6):748-59.

Zhang L, Zhang M, Yang S, Cao Y, Bingrong Zhang S, Yin L, Tian Y, Ma Y, Zhang A, Okunieff P, Zhang L. A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma. Br J Radiol. 2010 Aug;83(992):694-701.

Otterson MF, Leming SC, Fox CJ, Moulder JE. Propagation of giant migrating contractions between the small intestine, cecum and colon during radiation. Neurogastroenterol Motil. 2010 Aug;22(8):919-26. Epub 2010 Jun 7.

Sun H, Tsai Y, Nowak I, Dertinger SD, Wu JH, Chen Y. Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture. Mutat Res. 2011 Jan 10;718(1-2):38-43. Epub 2010 Nov 4.

Cohen EP, Pais P, Moulder JE. Chronic kidney disease after hematopoietic stem cell transplantation. Semin Nephrol. 2010 Nov;30(6):627-34.

Cohen EP, Fish BL, Moulder JE. Mitigation of radiation injuries via suppression of the renin-angiotensin system: emphasis on radiation nephropathy. Curr Drug Targets. 2010 Nov;11(11):1423-9.

Shuryak I, Sachs RK, Brenner DJ. Cancer risks after radiation exposure in middle age. J Natl Cancer Inst. 2010 Nov 3;102(21):1628-36. Epub 2010 Oct 25.

Liu C, Chen BJ, Deoliveira D, Sempowski GD, Chao NJ, Storms RW. Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation. Blood. 2010 Dec 16;116(25):5518-27. Epub 2010 Sep 10.

Epperly MW, Goff JP, Li S, Gao X, Wipf P, Dixon T, Wang H, Franicola D, Shen H, Rwigema JC, Kagan V, Bernard M, Greenberger JS. Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitis. In Vivo. 2010 Nov-Dec;24(6):811-9.

Stitt-Fischer MS, Ungerman RK, Wilen DS, Wasserloos K, Renz LM, Raub SE, Peterson J, Pearce LL. Manganese superoxide dismutase is not protective in bovine pulmonary artery endothelial cells at systemic oxygen levels. Radiat Res. 2010 Dec;174(6):679-90. Epub 2010 Sep 28.

Kim K, McBride WH. Modifying radiation damage. Curr Drug Targets. 2010 Nov;11(11):1352-65.

McDonald JT, Kim K, Norris AJ, Vlashi E, Phillips TM, Lagadec C, Della Donna L, Ratikan J, Szelag H, Hlatky L, McBride WH. Ionizing radiation activates the Nrf2 antioxidant response. Cancer Res. 2010 Nov 1;70(21):8886-95. Epub 2010 Oct 12.

Hafer K, Rivina Y, Schiestl RH. Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res. 2010 Dec;174(6):719-26. Epub 2010 Sep 20.

Brady S, Yoshizumi T, Toncheva G, Frus D. Implementation of radiochromic film dosimetry protocol for volumetric dose assessments to various organs during diagnostic CT procedures. Med Phys. 2010 Sep;37(9):4782-92.

Brady SL, Gunasingha R, Yoshizumi TT, Howell CR, Crowell AS, Fallin B, Tonchev AP, Dewhirst MW. A feasibility study using radiochromic films for fast neutron 2D passive dosimetry. Phys Med Biol. 2010 Sep 7;55(17):4977-92. Epub 2010 Aug 6.

Yakovlev VA, Rabender CS, Sankala H, Gauter-Fleckenstein B, Fleckenstein K, Batinic-Haberle I, Jackson I, Vujaskovic Z, Anscher MS, Mikkelsen RB, Graves PR. Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+). Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):547-54. Epub 2010

Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, Ting JP. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010 Oct 15;185(8):4515-9. Epub 2010 Sep 22.

Liu C, Chen BJ, Deoliveira D, Sempowski GD, Chao NJ, Storms RW. Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation. Blood. 2010 Dec 16;116(25):5518-27. Epub 2010 Sep 10.

Gokhale A, Rwigema JC, Epperly MW, Glowacki J, Wang H, Wipf P, Goff JP, Dixon T, Patrene K, Greenberger JS. Small molecule GS-nitroxide ameliorates ionizing irradiation-induced delay in bone wound healing in a novel murine model. In Vivo. 2010 Jul-Aug;24(4):377-85.

Rajagopalan MS, Stone B, Rwigema JC, Salimi U, Epperly MW, Goff J, Franicola D, Dixon T, Cao S, Zhang X, Buchholz BM, Bauer AJ, Choi S, Bakkenist C, Wang H, Greenberger JS. Intraesophageal manganese superoxide dismutase-plasmid liposomes ameliorates novel total-body and thoracic radiation sensitivity of NOS1-/- mice. Radiat Res. 2010 Sep;174(3):297-312.

Huang Z, Jiang J, Belikova NA, Stoyanovsky DA, Kagan VE, Mintz AH. Protection of normal brain cells from γ-irradiation-induced apoptosis by a mitochondria-targeted triphenyl-phosphonium-nitroxide: a possible utility in glioblastoma therapy. J Neurooncol. 2010 Oct;100(1):1-8. Epub 2010 Sep 12.

Epperly MW, Goff JP, Li S, Gao X, Wipf P, Dixon T, Wang H, Franicola D, Shen H, Rwigema JC, Kagan V, Bernard M, Greenberger JS. Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitis. In Vivo. 2010 Nov-Dec;24(6):811-9.

Stitt-Fischer MS, Ungerman RK, Wilen DS, Wasserloos K, Renz LM, Raub SE, Peterson J, Pearce LL. Manganese superoxide dismutase is not protective in bovine pulmonary artery endothelial cells at systemic oxygen levels. Radiat Res. 2010 Dec;174(6):679-90. Epub 2010 Sep 28.

Mussano F, Lee KJ, Zuk P, Tran L, Cacalano NA, Jewett A, Carossa S, Nishimura I. Differential effect of ionizing radiation exposure on multipotent and differentiation-restricted bone marrow mesenchymal stem cells. J Cell Biochem. 2010 Oct 1;111(2):322-32.

McDonald JT, Kim K, Norris AJ, Vlashi E, Phillips TM, Lagadec C, Della Donna L, Ratikan J, Szelag H, Hlatky L, McBride WH. Ionizing radiation activates the Nrf2 antioxidant response. Cancer Res. 2010 Nov 1;70(21):8886-95. Epub 2010 Oct 12.

Hafer K, Rivina Y, Schiestl RH. Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res. 2010 Dec;174(6):719-26. Epub 2010 Sep 20.

Shuryak I, Ullrich RL, Sachs RK, Brenner DJ. The balance between initiation and promotion in radiation-induced murine carcinogenesis. Radiat Res. 2010 Sep;174(3):357-66.

Brady S, Yoshizumi T, Toncheva G, Frus D. Implementation of radiochromic film dosimetry protocol for volumetric dose assessments to various organs during diagnostic CT procedures. Med Phys. 2010 Sep;37(9):4782-92.

Brady SL, Gunasingha R, Yoshizumi TT, Howell CR, Crowell AS, Fallin B, Tonchev AP, Dewhirst MW. A feasibility study using radiochromic films for fast neutron 2D passive dosimetry. Phys Med Biol. 2010 Sep 7;55(17):4977-92.

Yakovlev VA, Rabender CS, Sankala H, Gauter-Fleckenstein B, Fleckenstein K, Batinic-Haberle I, Jackson I, Vujaskovic Z, Anscher MS, Mikkelsen RB, Graves PR. Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+). Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):547-54.

Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, Ting JP. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010 Oct 15;185(8):4515-9.

Rajagopalan MS, Stone B, Rwigema JC, Salimi U, Epperly MW, Goff J, Franicola D, Dixon T, Cao S, Zhang X, Buchholz BM, Bauer AJ, Choi S, Bakkenist C, Wang H, Greenberger JS. Intraesophageal manganese superoxide dismutase-plasmid liposomes ameliorates novel total-body and thoracic radiation sensitivity of NOS1-/- mice. Radiat Res. 2010 Sep;174(3):297-312.

Huang Z, Jiang J, Belikova NA, Stoyanovsky DA, Kagan VE, Mintz AH. Protection of normal brain cells from γ-irradiation-induced apoptosis by a mitochondria-targeted triphenyl-phosphonium-nitroxide: a possible utility in glioblastoma therapy. J Neurooncol. 2010 Oct;100(1):1-8.

Mussano F, Lee KJ, Zuk P, Tran L, Cacalano NA, Jewett A, Carossa S, Nishimura I. Differential effect of ionizing radiation exposure on multipotent and differentiation-restricted bone marrow mesenchymal stem cells. J Cell Biochem. 2010 Oct 1;111(2):322-32.

Batinić-Haberle I, Rebouças JS, Spasojević I. Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential. Antioxid Redox Signal. 2010 Sep 15;13(6):877-918.

Otterson MF, Leming SC, Fox CJ, Moulder JE. Propagation of giant migrating contractions between the small intestine, cecum and colon during radiation. Neurogastroenterol Motil. 2010 Aug;22(8):919-26.

Patterson AD, Lanz C, Gonzalez FJ, Idle JR. The role of mass spectrometry-based metabolomics in medical countermeasures against radiation. Mass Spectrom Rev. 2010 May-Jun;29(3):503-21.

Hafer K, Rivina L, Schiestl RH. Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae. Radiat Res. 2010 Jun;173(6):802-8.

Vorotnikova E, Rosenthal RA, Tries M, Doctrow SR, Braunhut SJ. Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation. Radiat Res. 2010 Jun;173(6):748-59.

Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF. Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-κB. Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77.

Cha H, Lowe JM, Li H, Lee JS, Belova GI, Bulavin DV, Fornace AJ Jr. Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response. Cancer Res. 2010 May 15;70(10):4112-22.

Cui L, Pierce D, Light KE, Melchert RB, Fu Q, Kumar KS, Hauer-Jensen M. Sublethal total body irradiation leads to early cerebellar damage and oxidative stress. Curr Neurovasc Res. 2010 May;7(2):125-35.

Niu Y, Wang H, Wiktor-Brown D, Rugo R, Shen H, Huq MS, Engelward B, Epperly M, Greenberger JS. Irradiated esophageal cells are protected from radiation-induced recombination by MnSOD gene therapy. Radiat Res. 2010 Apr;173(4):453-61.

Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF. Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-kappaB. Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77.

Ryan CM, Souda P, Bassilian S, Ujwal R, Zhang J, Abramson J, Ping P, Durazo A, Bowie JU, Hasan SS, Baniulis D, Cramer WA, Faull KF, Whitelegge JP. Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol Cell Proteomics. 2010 May;9(5):791-803. Epub 2010 Jan 21.

Zhang L, Sun W, Wang J, Zhang M, Yang S, Tian Y, Vidyasagar S, Peña LA, Zhang K, Cao Y, Yin L, Wang W, Zhang L, Schaefer KL, Saubermann LJ, Swarts SG, Fenton BM, Keng PC, Okunieff P. Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation. Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):261-8.

Epperly M, Franicola D, Shields D, Rwigema J-C, Stone B, Zhang X, McBride W, Georges G, Wipf P, Greenberger JS. Screening of antimicrobial agents for in vitro radiation protection and mitigation capacity, including those used in supportive care regimens for bone marrow transplant recipients. In Vivo. 2010 Jan-Feb;24(1):9-19.

Muramoto GG, Russell JL, Safi R, Salter AB, Himburg HA, Daher P, Meadows SK, Doan P, Storms RW, Chao NJ, McDonnell DP, Chute JP. Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. Stem Cells. 2010 Mar 31;28(3):523-34.

McCurdy M, McAleer MF, Wei W, Ezhil M, Johnson V, Khan M, Baker J, Luo D, Ajani J, Guerrero T. Induction and concurrent taxanes enhance both the pulmonary metabolic radiation response and the radiation pneumonitis response in patients with esophagus cancer. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):816-23.

Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi J-T, Salter AB, Lento WE, Reya T, Chao NJ, Chute JP. Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med. 2010 Apr;16(4):475-82.

Garg S, Boerma M, Wang J, Fu Q, Loose DS, Kumar KS, Hauer-Jensen M. Influence of sublethal total-body irradiation on immune cell populations in the intestinal mucosa. Radiat Res. 2010 Apr;173(4):469-78.

Gauter-Fleckenstein B, Fleckenstein K, Owzar K, Jiang C, Reboucas JS, Batinic-Haberle I, Vujaskovic Z. Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage. Free Radic Biol Med. 2010 Apr 15;48(8):1034-43.

Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, Macvittie TJ, Mason KA, Medhora MM, Moulder JE, Okunieff P, Otterson MF, Robbins ME, Smathers JB, McBride WH. Animal models for medical countermeasures to radiation exposure. Radiat Res. 2010 Apr;173(4):557-78.

Araki S, Eitel JA, Batuello CN, Bijangi-Vishehsaraei K, Xie X-J, Danielpour D, Pollok KE, Boothman DA, Mayo LD. TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. J Clin Invest. 2010 Jan;120(1):290-302.

Garty G, Chen Y, Salerno A, Turner H, Zhang J, Lyulko O, Bertucci A, Xu Y, Wang H, Simaan N, Randers-Pehrson G, Yao YL, Amundson SA, Brenner DJ. The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys. 2010 Feb;98(2):209-17.

Xie D, Gore C, Liu J, Pong R-C, Mason R, Hao G, Long M, Kabbani, W, Yu L, Zhang H, Chen H, Sun X, Boothman DA, Min Wang, Hsieh J-T. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2485-90.

Brengues M, Paap B, Bittner M, Amundson S, Seligmann B, Korn R, Lenigk R, Zenhausern F. Biodosimetry on small blood volume using gene expression assay. Health Phys. 2010 Feb;98(2):179-85.

Partridge MA, Chai Y, Zhou H, Hei TK. High-throughput antibody-based assays to identify and quantify radiation-responsive protein biomarkers. Int J Radiat Biol. 2010 Apr;86(4):321-8.

Schaue D, McBride WH. Links between innate immunity and normal tissue radiobiology. Radiat Res. 2010 Apr;173(4):406-17.

Jenrow KA, Brown SL, Liu J, Kolozsvary A, Lapanowski K, Kim JH. Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus. Radiat Oncol. 2010 Feb 1;5:6.

Prasanna PGS, Blakely WF, Bertho J-M, Chute JP, Cohen EP, Goans RE, Grace MB, Lillis-Hearne PK, Lloyd DC, Lutgens LCHW, Meineke V, Ossetrova NI, Romanyukha A, Saba JD, Weisdorf DJ, Wojcik A, Yukihara EG, Pellmar TC. Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop. Radiat Res. 2010 Feb;173(2):245-53.

Szabo S, Ghosh SN, Fish BL, Bodiga S, Tomic R, Kumar G, Morrow NV, Moulder JE, Jacobs ER, Medhora M. Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic x radiation in rats. Radiat Res. 2010 Apr;173(4):545-56.

Brown SL, Kolozsvary A, Liu J, Jenrow KA, Ryu S, Kim JH. Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality. Radiat Res. 2010 Apr;173(4):462-8.

Nicolalde RJ, Gougelet RM, Rea M, Williams BB, Dong R, Kmiec MM, Lesniewski PN; Swartz HM. The view from the trenches: part 2-technical considerations for EPR screening. Health Phys. 2010 Feb;98(2):128-35.

Gougelet RM, Rea ME, Nicolalde RJ, Geiling JA, Swartz HM. The view from the trenches: part 1-emergency medical response plans and the need for EPR screening. Health Phys. 2010 Feb;98(2):118-27.

Pollock JD, Williams BB, Sidabras JW, Grinberg O, Salikhov I, Lesniewski P, Kmiec M, Swartz HM. Surface loop resonator design for in vivo EPR tooth dosimetry using finite element analysis. Health Phys. 2010 Feb;98(2):339-44.

Rea ME, Gougelet RM, Nicolalde RJ, Geiling JA, Swartz HM. Proposed triage categories for large-scale radiation incidents using high-accuracy biodosimetry methods. Health Phys. 2010 Feb;98(2):136-44.

Black PJ, Swarts SG. Ex vivo analysis of irradiated fingernails: chemical yields and properties of radiation-induced and mechanically-induced radicals. Health Phys. 2010 Feb;98(2):301-8.

Wilcox DE, He X, Gui J, Ruuge AE, Li H, Williams BB, Swartz HM. Dosimetry based on EPR spectral analysis of fingernail clippings. Health Phys. 2010 Feb;98(2):309-17.

Williams BB, Dong R, Kmiec M, Burke G, Demidenko E, Gladstone D, Nicolalde RJ, Sucheta A, Lesniewski Piotr, Swartz HM. Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Phys. 2010 Feb;98(2):327-38.

Swartz HM, Flood AB, Gougelet RM, Rea ME, Nicolalde RJ, Williams BB. A critical assessment of biodosimetry methods for large-scale incidents. Health Phys. 2010 Feb;98(2):95-108.

Bentzen SM, Parliament M, Deasy JO, Dicker A, Curran WJ, Williams JP, Rosenstein BS. Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S145-50.

Bhogal N, Kaspler P, Jalali F, Hyrien O, Chen R, Hill RP, Bristow RG. Late residual gamma-H2AX foci in murine skin are dose responsive and predict radiosensitivity in vivo. Radiat Res. 2010 Jan;173(1):1-9.

Chen Y, Tsai Y, Nowak I, Wang N, Hyrien O, Wilkins R, Ferrarotto C, Sun H, Dertinger SD.Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model. Health Phys. 2010 Feb;98(2):218-27.

Nicolalde RJ, Gougelet RM, Rea M, Williams BB, Dong R, Kmiec MM, Lesniewski PN, Swartz HM. The view from the trenches: part 2-technical considerations for EPR screening. Health Phys. 2010 Feb;98(2):128-35.

Pollock JD, Williams BB, Sidabras JW, Grinberg O, Salikhov I, Lesniewski P, Kmiec M, Swartz HM. Surface loop resonator design for in vivo EPR tooth dosimetry using finite element analysis. Health Phys. 2010 Feb;98(2):339-44.

Rea ME, Gougelet RM, Nicolalde RJ, Geiling JA, Swartz HM. Proposed triage categories for large-scale radiation incidents using high-accuracy biodosimetry methods. Health Phys. 2010 Feb;98(2):136-44.

Black PJ, Swarts SG. Ex vivo analysis of irradiated fingernails: chemical yields and properties of radiation-induced and mechanically-induced radicals. Health Phys. 2010 Feb;98(2):301-8.

Wilcox DE, He X, Gui J, Ruuge AE, Li H, Williams BB, Swartz HM. Dosimetry based on EPR spectral analysis of fingernail clippings. Health Phys. 2010 Feb;98(2):309-17.

Williams BB, Dong R, Kmiec M, Burke G, Demidenko E, Gladstone D, Nicolalde RJ, Sucheta A, Lesniewski P, Swartz HM. Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Phys. 2010 Feb;98(2):327-38.

Swartz HM, Flood AB, Gougelet RM, Rea ME, Nicolalde RJ, Williams BB. A critical assessment of biodosimetry methods for large-scale incidents. Health Phys. 2010 Feb;98(2):95-108.

Ghosh SN, Zhang R, Fish BL, Semenenko VA, Li XA, Moulder JE, Jacobs ER, Medhora M. Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis. Int J Radiat Oncol Biol Phys. 2009 Dec 1;75(5):1528-36.

Baker JE, Fish BL, Su J, Haworth ST, Strande JL, Komorowski RA, Migrino RQ, Doppalapudi A, Harmann L, Allen Li X, Hopewell JW, Moulder JE. 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model. Int J Radiat Biol. 2009 Dec;85(12):1089-100.

Sharma M, Halligan BD, Wakim BT, Savin VJ, Cohen EP, Moulder JE. The urine proteome for radiation biodosimetry: effect of total body vs. local kidney irradiation. Health Phys. 2010 Feb;98(2):186-95.

Garty G, Chen Y, Salerno A, Turner H, Zhang J, Lyulko O, Bertucci A, Xu Y, Wang H, Simaan N, Randers-Pehrson G, Yao YL, Amundson SA, Brenner DJ. The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys. 2010 Feb;98(2):209-17.

Brengues M, Paap B, Bittner M, Amundson S, Seligmann B, Korn R, Lenigk R, Zenhausern F. Biodosimetry on small blood volume using gene expression assay. Health Phys. 2010 Feb;98(2):179-85.

Valuckaite V, Zaborina O, Long J, Hauer-Jensen M, Wang J, Holbrook C, Zaborin A, Drabik K, Katdare M, Mauceri H, Weichselbaum R, Firestone MA, Lee KY, Chang EB, Matthews J, Alverdy JC. Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1041-52.

Jha S, Ting JP.Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. J Immunol. 2009 Dec 15;183(12):7623-9.

Kos I, Benov L, Spasojević I, Rebouças JS, Batinić-Haberle I. High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli. J Med Chem. 2009 Dec 10;52(23):7868-72.

Jackson IL, Vujaskovic Z, Down JD. Revisiting strain-related differences in radiation sensitivity of the mouse lung: recognizing and avoiding the confounding effects of pleural effusions. Radiat Res. 2010 Jan;173(1):10-20.

Chute JP, Ross JR, McDonnell DP. Minireview: Nuclear receptors, hematopoiesis, and stem cells. Mol Endocrinol. 2010 Jan;24(1):1-10. Epub 2009 Nov 24.

2009

Jiang J, Stoyanovsky DA, Belikova NA, Tyurina YY, Zhao Q, Tungekar MA, Kapralova V, Huang Z, Mintz AH, Greenberger JS, Kagan VE.A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator. Radiat Res. 2009 Dec;172(6):706-17.

Bhogal, Nirmal; Jalali, Farid; Bristow, Robert G. Microscopic imaging of DNA repair foci in irradiated normal tissues. Int J Radiat Biol. 2009 Sep;85(9):732-46.

Para AE, Bezjak A, Yeung IW, Van Dyk J, Hill RP. Effects of genistein following fractionated lung irradiation in mice. Radiother Oncol. 2009 Sep;92(3):500-10. Epub 2009 May 9.

Chan CY, Schiestl RH. Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res. 2009 Aug;172(2):141-51.

Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA. Nonaminoglycoside compounds induce readthrough of nonsense mutations. J Exp Med. 2009 Sep 28;206(10):2285-97. Epub 2009 Sep 21.

Nahas SA, Gatti RA. DNA double strand break repair defects, primary immunodeficiency disorders, and 'radiosensitivity'. Curr Opin Allergy Clin Immunol. 2009 Dec;9(6):510-6.

Graves SS, Stone D, Loretz C, Peterson L, McCune JS, Mielcarek M, Storb R. Establishment of long-term tolerance to SRBC in dogs by recombinant canine CTLA4-Ig. Transplantation. 2009 Aug 15;88(3):317-22.

Ding Y, Rotta M, Graves SS, Storer BE, Peterson LJ, Sale GE, Forough R, Zellmer E, Georges GE, Sandmaier BM, Kuhr CS, Storb R. Delaying DLA-haploidentical hematopoietic cell transplantation after total body irradiation. Biol Blood Marrow Transplant. 2009 Oct;15(10):1244-50. Epub 2009 Aug 3.

Brenner DJ. Extrapolating radiation-induced cancer risks from low doses to very low doses. Health Phys. 2009 Nov;97(5):505-9.

Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. J Immunol. 2009 Aug 1;183(3):2008-15. Epub 2009 Jul 8.

Doyle T, Bryant L, Batinic-Haberle I, Little J, Cuzzocrea S, Masini E, Spasojevic I, Salvemini D. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. Neuroscience. 2009 Dec 1;164(2):702-10. Epub 2009 Jul 14.

Goff JP, Shields DS, Seki M, Choi S, Epperly MW, Dixon T, Wang H, Bakkenist CJ, Dertinger SD, Torous DK, Wittschieben J, Wood RD, Greenberger JS. Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Radiat Res. 2009 Aug;172(2):165-74.

Belikova NA, Tyurina YY, Borisenko G, Tyurin V, Samhan Arias AK, Yanamala N, Furtmüller PG, Klein-Seetharaman J, Obinger C, Kagan VE. Heterolytic reduction of fatty acid hydroperoxides by cytochrome c/cardiolipin complexes: antioxidant function in mitochondria. J Am Chem Soc. 2009 Aug 19;131(32):11288-9.

Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS. The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair. In Vivo. 2009 Sep-Oct;23(5):717-26.

Liu H, Dömling A. One-pot synthesis of highly functionalized seleno amino acid derivatives. Chem Biol Drug Des. 2009 Sep;74(3):302-8.

Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2863-72. Epub 2009 Mar 13.

Jiang J, McDonald PR, Dixon TM, Franicola D, Zhang X, Nie S, Epperly LD, Huang Z, Kagan VE, Lazo JS, Epperly MW, Greenberger JS.Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector. Radiat Res. 2009 Oct;172(4):414-22.

Cummings RJ, Mitra S, Foster TH, Lord EM. Migration of skin dendritic cells in response to ionizing radiation exposure. Radiat Res. 2009 Jun;171(6):687-97.

Kaspler P, Pintilie M, Hill RP. Dynamics of micronuclei in rat skin fibroblasts after X irradiation. Radiat Res. 2009 Jul;172(1):106-13.

Zhang H, Zhang SB, Sun W, Yang S, Zhang M, Wang W, Liu C, Zhang K, Swarts S, Fenton BM, Keng P, Maguire D, Okunieff P, Zhang L. B1 sequence-based real-time quantitative PCR: a sensitive method for direct measurement of mouse plasma DNA levels after gamma irradiation. Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1592-9.

Birmingham A, Selfors LM, Forster T, Wrobel D, Kennedy CJ, Shanks E, Santoyo-Lopez J, Dunican DJ, Long A, Kelleher D, Smith Q, Beijersbergen RL, Ghazal P, Shamu CE. Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods. 2009 Aug;6(8):569-75.

Ivey RG, Subramanian O, Lorentzen TD, Paulovich AG. Antibody-based screen for ionizing radiation-dependent changes in the Mammalian proteome for use in biodosimetry. Radiat Res. 2009 May;171(5):549-61.

Yoon AJ, Shen J, Wu HC, Angelopoulos C, Singer SR, Chen R, Santella RM. Expression of activated checkpoint kinase 2 and histone 2AX in exfoliative oral cells after exposure to ionizing radiation. Radiat Res. 2009 Jun;171(6):771-5.

Tyburski JB, Patterson AD, Krausz KW, Slavík J, Fornace AJ Jr, Gonzalez FJ, Idle JR. Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice. Radiat Res. 2009 Jul;172(1):42-57.

Fu Q, Berbée M, Boerma M, Wang J, Schmid HA, Hauer-Jensen M.The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion. Radiat Res. 2009 Jun;171(6):698-707.

Dertinger SD, Bemis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y. Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age. Mutat Res, 2009 Apr 30; 675: 77-80

Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH. N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res. 2009 Jun 1;665(1-2):37-43. Epub 2009 Mar 13.

Pollard JM, Reboucas JS, Durazo A, Kos I, Fike F, Panni M, Gralla EB, Valentine JS, Batinic-Haberle I, Gatti RA. Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells. Free Radic Biol Med. 2009 Aug 1; 250-60

Tyurin VA, Tyurina YY, Jung M-Y, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13

Kagan VE, Bayir HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G.Cytochrome c/cardiolipin relations in mitochondria: A kiss of death. Free Radic Biol Med. 2009 Mar 11

Faraji AH, Wipf P. Nanoparticles in cellular drug delivery. Bioorg Med Chem. 2009 Apr 15; 2950-62

Belikova NA, Jiang J, Stoyanovsky DA, Glumac A, Bayir H, Greenberger JS, Kagan VE. Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis. FEBS Lett. 2009 Jun 18; 583: 1945-50

Sen I, Verdicchio MP, Jung S, Trevino R, Bittner M, Kim S. Context-specific gene regulations in cancer gene expression data. Pac Symp Biocomput. 2009:75-86.

Zhang H, Maguire D, Swarts S, Sun W, Yang S, Wang W, Liu C, Zhang M, Zhang D, Zhang L, Zhang K, Keng P, Zhang L, Okunieff P. Replication of murine mitochondrial DNA following irradiation. Adv Exp Med Biol. 2009;645:43-8.

Ghosh SN, Wu Q, Mäder M, Fish BL, Moulder JE, Jacobs ER, Medhora M, Molthen RC. Vascular injury after whole thoracic x-ray irradiation in the rat. Int J Radiat Oncol Biol Phys. 2009 May 1;74(1):192-9.

Lenarczyk M, Cohen EP, Fish BL, Irving AA, Sharma M, Driscoll CD, Moulder JE. Chronic oxidative stress as a mechanism for radiation nephropathy. Radiat Res. 2009 Feb;171(2):164-72.

Scuric Z, Chan CY, Hafer K, Schiestl RH. Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res. 2009 Apr;171(4):454-63.

Nahas SA, Butch AW, Du L, Gatti RA. Rapid flow cytometry-based structural maintenance of chromosomes 1 (SMC1) phosphorylation assay for identification of ataxia-telangiectasia homozygotes and heterozygotes. Clin Chem. 2009 Mar;55(3):463-72. Epub 2009 Jan 15.

Mitui M, Nahas SA, Du LT, Yang Z, Lai CH, Nakamura K, Arroyo S, Scott S, Purayidom A, Concannon P, Lavin M, Gatti RA. Functional and computational assessment of missense variants in the ataxia-telangiectasia mutated (ATM) gene: mutations with increased cancer risk. Hum Mutat. 2009 Jan;30(1):12-21.

Piening BD, Wang P, Subramanian A, Paulovich AG. A radiation-derived gene expression signature predicts clinical outcome for breast cancer patients. Radiat Res. 2009 Feb;171(2):141-54.

Zhou H, Hong M, Chai Y, Hei TK. Consequences of cytoplasmic irradiation: studies from microbeam. J Radiat Res (Tokyo). 2009 Mar;50 Suppl A:A59-65.

Zhao C, Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, VanArsdale T, Beachy PA, Reya T. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature. 2009 Apr 9;458(7239):776-9.

Wise-Faberowski L, Warner DS, Spasojevic I, Batinic-Haberle I. Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death. Free Radic Res. 2009 Apr;43(4):329-39.

Kos I, Rebouças JS, DeFreitas-Silva G, Salvemini D, Vujaskovic Z, Dewhirst MW, Spasojević I, Batinić-Haberle I. Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins. Free Radic Biol Med. 2009 Jul 1;47(1):72-8.

Kagan VE, Bayir A, Bayir H, Stoyanovsky D, Borisenko GG, Tyurina YY, Wipf P, Atkinson J, Greenberger JS, Chapkin RS, Belikova NA.Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery. Mol Nutr Food Res. 2009 Jan;53(1):104-14.

Greenberger JS.Radioprotection. In Vivo. 2009 Mar-Apr;23(2):323-36.

Faraji AH, Wipf P. Nanoparticles in cellular drug delivery. Bioorg Med Chem. 2009 Apr 15;17(8):2950-62.

2008

Sharma M, Halligan BD, Wakim BT, Savin VJ, Cohen EP, Moulder JE. The urine proteome as a biomarker of radiation injury. Proteomics Clin Appl. 2008 Jun 18;2(7-8):1065-1086.

Chen Y, Pandya KJ, Feins R, Johnstone DW, Watson T, Smudzin T, Keng PC. Toxicity profile and pharmacokinetic study of a phase I low-dose schedule-dependent radiosensitizing paclitaxel chemoradiation regimen for inoperable non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):407-13.

Cummings RJ, Mitra S, Lord EM, Foster TH. Antibody-labeled fluorescence imaging of dendritic cell populations in vivo. J Biomed Opt. 2008 Jul-Aug;13(4):044041.

Ehlayel M, de Beaucoudrey L, Fike F, Nahas SA, Feinberg J, Casanova JL, Gatti RA. Simultaneous presentation of 2 rare hereditary immunodeficiencies: IL-12 receptor beta1 deficiency and ataxia-telangiectasia. J Allergy Clin Immunol. 2008 Dec;122(6):1217-9.

Kumar S, Kolozsvary A, Kohl R, Lu M, Brown S, Kim JH. Radiation-induced skin injury in the animal model of scleroderma: implications for post-radiotherapy fibrosis. Radiat Oncol. 2008 Nov 24;3:40.

Spasojević I, Chen Y, Noel TJ, Fan P, Zhang L, Rebouças JS, St Clair DK, Batinić-Haberle I. Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice. Free Radic Biol Med. 2008 Oct 1;45(7):943-9.

Rebouças JS, Spasojević I, Batinić-Haberle I. Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes. J Pharm Biomed Anal. 2008 Nov 4;48(3):1046-9.

Borisenko GG, Kapralov AA, Tyurin VA, Maeda A, Stoyanovsky DA, Kagan VE. Molecular design of new inhibitors of peroxidase activity of cytochrome c/cardiolipin complexes: fluorescent oxadiazole-derivatized cardiolipin. Biochemistry. 2008 Dec 23;47(51):13699-710.2008

Epperly MW, Dixon T, Wang H, Schlesselman J, Franicola D, Greenberger JS. Modulation of radiation-induced life shortening by systemic intravenous MnSOD-plasmid liposome gene therapy. Radiat Res. 2008 Oct;170(4):437-43.

Straume T, Amundson SA, Blakely WF, Burns FJ, Chen A, Dainiak N, Franklin S, Leary JA, Loftus DJ, Morgan WF, Pellmar TC, Stolc V, Turteltaub KW, Vaughan AT, Vijayakumar S, Wyrobek AJ. NASA Radiation Biomarker Workshop, September 27-28, 2007. Radiat Res. 2008 Sep;170(3):393-405.

Tyurin VA, Tyurina YY, Kochanek PM, Hamilton R, DeKosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of programmed cell death. Methods Enzymol. 2008;442:375-93.

Hart JP, McCurdy MR, Ezhil M, Wei W, Khan M, Luo D, Munden RF, Johnson VE, Guerrero TM. Radiation pneumonitis: correlation of toxicity with pulmonary metabolic radiation response. Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):967-71.

Brenner DJ. The linear-quadratic model is an appropriate methodology for determining isoeffective doses at large doses per fraction. Semin Radiat Oncol. 2008 Oct;18(4):234-9.

Okunieff P, Chen Y, Maguire DJ, Huser AK. Molecular markers of radiation-related normal tissue toxicity. Cancer Metastasis Rev. 2008 Sep;27(3):363-74.

DeFreitas-Silva G, Rebouças JS, Spasojević I, Benov L, Idemori YM, Batinić-Haberle I. SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself. Arch Biochem Biophys. 2008 Sep 1;477(1):105-12.

Yan S, Brown SL, Kolozsvary A, Freytag SO, Lu M, Kim JH.Mitigation of radiation-induced skin injury by AAV2-mediated MnSOD gene therapy. J Gene Med. 2008 Sep;10(9):1012-8.

Rebouças JS, DeFreitas-Silva G, Spasojević I, Idemori YM, Benov L, Batinić-Haberle I. Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier. Free Radic Biol Med. 2008 Jul 15;45(2):201-10.

Congdon KL, Reya T. Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system. Curr Opin Immunol. 2008 Jun;20(3):302-7.

Batinic-Haberle I, Benov LT. An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. Free Radic Res. 2008 Jul;42(7):618-24.

JH Kim, SL Brown SL, KA Jenrow, S Ryu: Mechanisms of radiation-induced brain toxicity and implications for future clinical trials. J Neuro-Oncol. 87:279-286, 2008

Reboucas, JS, Spasojevic, I, Batinic-Haberle, I. Pure MnTBAP has no SOD activity in aqueous systems, A case of structure-activity relationship as a watchdog mechanism in experimental therapeutics and biology. J Inorg Biol Chem. 2008, 13, 289-302.

Jochum C, Beste M, Stone D, Graves SS, Storb R. Development and in vitro characterization of canine CD40-lg. Vet Immunol Immunopathol. 123: 260-265, 2008.

Huang Z, Jiang J, Tyurin VA, Zhao Q, Mnuskin A, Ren J, Belikova NA, Feng W, Kurnikov IV, Kagan VE.Cardiolipin deficiency leads to decreased cardiolipin peroxidation and increased resistance of cells to apoptosis. Free Radic Biol Med. 2008 Jun 1;44(11):1935-44.

Bayir H, Kagan VE. Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis - there is nothing more practical than a good theory. Crit Care. 2008; 12(1):206.

Tyburski JB, Patterson AD, Krausz KW, Slavík J, Fornace AJ, Gonzalez FJ, Idle JR. Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice. Radiat Res. 2008 Jul;170(1):1-14.

Paul S, Amundson SA. Development of gene expression signatures for practical radiation biodosimetry. Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):1236-1244.

Zhang X, Epperly MW, Kay MA, Smith T, Franicola D, Greenberger B, Komanduri P, Greenberger JS. Radioprotection In Vitro and In Vivo by Mini Circle Plasmid Containing the Human Manganese Superoxide Dismutase (MnSOD) Transgene. Hum Gene Ther. 2008 Aug;19(8):820-6.

Congdon KL, Voermans C, Ferguson EC, DiMascio LN, Uqoezwa M, Zhao C, Reya T. Activation of Wnt signaling in hematopoietic regeneration. Stem Cells. 2008 May;26(5):1202-10.

Zhang R, Ghosh S, Zhu D, North P, Fish B, Morrow N, Lowry T, Nanchal R, Jacobs E, Moulder J, Medhora M. Structural and functional alterations in the rat lung following whole thoracic irradiation with moderate doses: Injury and recovery. Int J Radiat Biol. 2008 June;84(6):487–497.

Ma X, Chen C, Krausz KW, Idle JR, Gonzalez FJ. A metabolomic perspective of melatonin metabolism in the mouse. Endocrinology. 2008 Apr;149(4):1869-79.

Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg G, Chao NJ, Nevins JR, Chute JP. Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. PLoS ONE. 2008 Apr 2;3(4):e1912.

Rebouças JS, Spasojević I, Tjahjono DH, Richaud A, Méndez F, Benov L, Batinić-Haberle I. Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution. Dalton Trans. 2008 Mar 7;(9):1233-42.

Blakaj A, Lin H. Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem. 2008 Apr 11;283(15):9505-8.

Gauter-Fleckenstein B, Fleckenstein K, Owzar K, Jiang C, Batinic-Haberle I, Vujaskovic Z. Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection. Free Radic Biol Med. 2008 Mar 15;44(6):982-9.

Lupu M, Gooley T, Zellmer E, Graves SS, Storb R. Principles of peripheral blood mononuclear cell apheresis in a preclinical canine model of hematopoietic cell transplantation. J Vet Intern Med. 2008 Jan-Feb;22(1):74-82.

Stoyanovsky DA, Vlasova II, Belikova NA, Kapralov A, Tyurin V, Kagan VE. Activation of NO donors in mitochondria: peroxidase metabolism of (2-hydroxyamino-vinyl)-triphenyl-phosphonium by cytochrome c releases NO and protects cells against apoptosis. FEBS Lett. 2008 Mar 5;582(5):725-8.

Hafer K, Iwamoto KS, Schiestl RH. Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res. 2008 Apr;169(4):460-8.

Hafer K, Konishi T, Schiestl RH. Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method. Radiat Res. 2008 Apr;169(4):469-73.

Brown SL, Kolozsvary A, Liu J, Ryu S, Kim JH. Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. Radiat Res. 2008 Apr;169(4):474-8.

Sun W, Wang W, Kim J, Keng P, Yang S, Zhang H, Liu C, Okunieff P, Zhang L. Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment. Adv Exp Med Biol. 2008;614:179-86.

Okunieff P, Swarts S, Keng P, Sun W, Wang W, Kim J, Yang S, Zhang H, Liu C, Williams JP, Huser AK, Zhang L. Antioxidants reduce consequences of radiation exposure. Adv Exp Med Biol. 2008;614:165-78.

Patterson AD, Li H, Eichler GS, Krausz KW, Weinstein JN, Fornace AJ Jr, Gonzalez FJ, Idle JR. UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation. Anal Chem. 2008 Feb 1;80(3):665-74.

Tyurina YY, Tyurin VA, Epperly MW, Greenberger JS, Kagan VE. Oxidative lipidomics of gamma-irradiation-induced intestinal injury. Free Radic Biol Med. 2008 Feb 1;44(3):299-314.

Jiang J, Huang Z, Zhao Q, Feng W, Belikova NA, Kagan VE. Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis. Biochem Biophys Res Commun. 2008 Mar 28;368(1):145-50.

Cavalieri S, Funaro A, Pappi P, Migone N, Gatti RA, Brusco A. Large Genomic mutations within the ATM gene detected by MLPA, including a duplication of 41 kb from exon 4 to 20. Ann Hum Genet. 2008 Jan;72(Pt 1):10-8.

Jiang J, Belikova NA, Hoye AT, Zhao Q, Epperly MW, Greenberger JS, Wipf P, Kagan VE. A mitochondria-targeted nitroxide/hemigramicidin s conjugate protects mouse embryonic cells against gamma irradiation. Int J Radiat Oncol Biol Phys. 2008 Mar 1;70(3):816-25.

2007

Lahaye, D, Muthukumaran, K, Gryko, D, Hung, C-H, Reboucas, JS, Spasojevic, I, Batinic-Haberle, I, Lindsey, JS. Design and synthesis of manganese porphyrins with tailored lipophilicity: Investigation of redox properties and superoxide dismutase activity. Biorg Med Chem. 2007, 15, 7066-7086.

Hill RP, Kaspler P, Griffin AM, O'Sullivan B, Catton C, Alasti H, Abbas A, Heydarian M, Ferguson P, JS Wunder, Bell RS. Studies of the in vivo radiosensitivity of human skin fibroblasts. Radiother Oncol. 2007 Jul; 84(1): 75-83.

Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry. Mutat Res. 634:119-125, 2007.

Ambrose M, Goldstine JV, Gatti RA. Intrinsic mitochondria! dysfunction in ATM-deficient lymphoblastoid cells. Hum Mol Genet 16: 2154-64, 2007.

Zhao C, Blum J, Chen A, Kwon HY, Jung SH, Cook JM, Lagoo A, Reya T. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell. 2007 Dec;12(6):528-41.

Moore CB, Medina MA, van Deventer HW, O'Connor BP, Cameron S, Taxman DJ, Maile R, Ting JP, Cairns BA. Downregulation of immune signaling genes in patients with large surface burn injury. J Burn Care Res. 2007 Nov-Dec;28(6):879-87.

Kapralov AA, Kurnikov IV, Vlasova II, Belikova NA, Tyurin VA, Basova LV, Zhao Q, Tyurina YY, Jiang J, Bayir H, Vladimirov YA, Kagan VE. The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. Biochemistry. 2007 Dec 11;46(49):14232-44.

Romanyukha A, Trompier F, Leblanc B, Calas C, Clairand I, Mitchell CA, Smirniotopoulos JG, Swartz HM. EPR dosimetry in chemically treated fingernails. Radiat Meas. 2007 42(6-7):1110-1113.

Trompier F, Kornak L, Calas C, Romanyukha A, Leblanc B, Mitchell CA, Swartz HM, Clairand I. Protocol for emergency EPR dosimetry in fingernails. Radiat Meas. 2007 42(6-7):1085-1088.

Brenner DJ, Shuryak I, Russo S, Sachs RK. Reducing second breast cancers: a potential role for prophylactic mammary irradiation. J Clin Oncol. 2007 Nov 1;25(31):4868-72.

Kim S, Sen I, Bittner M. Mining molecular contexts of cancer via in-silico conditioning. Comput Syst Bioinformatics Conf. 2007;6:169-79.

Fung H, Liu P, Demple B. ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis. Mol Cell Biol. 2007 Dec;27(24):8834-47. Epub 2007 Oct 15.

Narciso L, Fortini P, Pajalunga D, Franchitto A, Liu P, Degan P, Frechet M, Demple B, Crescenzi M, Dogliotti E. Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17010-5. Epub 2007 Oct 16.

Belikova NA, Jiang J, Tyurina YY, Zhao Q, Epperly MW, Greenberger J, Kagan VE. Cardiolipin-specific peroxidase reactions of cytochrome C in mitochondria during irradiation-induced apoptosis. Int J Radiat Oncol Biol Phys. 2007 Sep 1;69(1):176-86.

Hontzeas N, Hafer K, Schiestl RH. Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries. Mutat Res. 2007 Dec 1;634(1-2):228-34. Epub 2007 Jul 10.

Hill RP, Perris R. "Destemming" cancer stem cells. J Natl Cancer Inst. 2007 Oct 3;99(19):1435-40. Epub 2007 Sep 25. Review.

Brenner DJ, Hall EJ. Computed tomography--an increasing source of radiation exposure. N Engl J Med. 2007 Nov 29;357(22):2277-84. Review.

Romanyukha A, Mitchell CA, Schauer DA, Romanyukha L, Swartz HM. Q-band EPR biodosimetry in tooth enamel microsamples: feasibility test and comparison with x-band. Health Phys. 2007 Dec;93(6):631-5.

Kohl RR, Kolozsvary A, Brown SL, Zhu G, Kim JH. Differential radiation effect in tumor and normal tissue after treatment with ramipril, an angiotensin-converting enzyme inhibitor. Radiat Res. 2007 Oct;168(4):440-5.

Zabrouskov V, Whitelegge JP. Increased coverage in the transmembrane domain with activated-ion electron capture dissociation for top-down Fourier-transform mass spectrometry of integral membrane proteins. J Proteome Res. 2007 Jun;6(6):2205-10.

Landmark H, Nahas SA, Aaroe J, Gatti R, Borresen-Dale AL, Rodningen OK. Transcriptional response to ionizing radiation in human radiation sensitive cell lines. Radiother Oncol. 2007 Jun;83(3):256-60.

Lavin MF, Gueven N, Bottle S, Gatti RA. Current and potential therapeutic strategies for the treatment of ataxia-telangiectasia. Br Med Bull. 2007;81-82:129-47.

Hafer K, Iwamoto KK, Scuric Z, Schiestl RH. Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res. 2007 Aug;168(2):168-74.

Otterson MF. Effects of radiation upon gastrointestinal motility. World J Gastroenterol. 2007 May 21;13(19):2684-92.

Bristow RG, Ozcelik H, Jalali F, Chan N, Vesprini D. Homologous recombination and prostate cancer: a model for novel DNA repair targets and therapies. Radiother Oncol. 2007 Jun;83(3):220-30.

Su Y, Yang S, Xiao Z, Wang W, Okunieff P, Zhang L. Triptolide alters mitochondrial functions. Adv Exp Med Biol. 2007;599:139-46.

Venkataraman GM, Stroup P, Graves SS, Storb R. An improved method for dog leukocyte antigen 88 typing and two new major histocompatibility complex class I alleles, DLA-88*01101 and DLA-88*01201. Tissue Antigens. 2007 Jul;70(1):53-7.

Fernandes ND, Sun Y, Price BD. Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells. J Biol Chem. 2007 Jun 1;282(22):16577-84.

Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, Shimamura A, D'Andrea AD. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest. 2007 May;117(5):1440-9.

Spasojevic I, Chen Y, Noel TJ, Yu Y, Cole MP, Zhang L, Zhao Y, St Clair DK, Batinic-Haberle I. Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria. Free Radic Biol Med. 2007 Apr 15;42(8):1193-200.

Zhen Y, Krausz KW, Chen C, Idle JR, Gonzalez FJ. Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. Mol Endocrinol. 2007 Sep;21(9):2136-51.

Ku WW, Aubrecht J, Mauthe RJ, Schiestl RH, Fornace AJ Jr. Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment. Toxicol Sci. 2007 Sep;99(1):20-5.

Ryu S, Kolozsvary A, Jenrow KA, Brown SL, Kim JH. Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: importance of ramipril dose and treatment time. J Neurooncol. 2007 Apr;82(2):119-24.

Du L, Pollard JM, Gatti RA. Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6007-12.

Bayir H, Tyurin VA, Tyurina YY, Viner R, Ritov V, Amoscato AA, Zhao Q, Zhang XJ, Janesko-Feldman KL, Alexander H, Basova LV, Clark RS, Kochanek PM, Kagan VE. Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis. Ann Neurol. 2007 Aug 8;62(2):154-69.

Al-Mutairi DA, Craik JD, Batinic-Haberle I, Benov LT. Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin. Biochim Biophys Acta. 2007 Jun 23 [Epub ahead of print].

Jiang J, Kurnikov I, Belikova NA, Xiao J, Zhao Q, Amoscato AA, Braslau R, Studer A, Fink MP, Greenberger JS, Wipf P, Kagan VE. Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides. J Pharmacol Exp Ther. 2007 Mar;320(3):1050-60.

Tyurina YY, Basova LV, Konduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B, Kagan VE. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J Biol Chem. 2007 Mar 16;282(11):8498-509.

Basova LV, Kurnikov IV, Wang L, Ritov VB, Belikova NA, Vlasova II, Pacheco AA, Winnica DE, Peterson J, Bayir H, Waldeck DH, Kagan VE. Cardiolipin switch in mitochondria: shutting off the reduction of cytochrome c and turning on the peroxidase activity. Biochemistry. 2007 Mar 20;46(11):3423-34.

Tyurin VA, Tyurina YY, Osipov AN, Belikova NA, Basova LV, Kapralov AA, Bayir H, Kagan VE. Interactions of cardiolipin and lyso-cardiolipins with cytochrome c and tBid: conflict or assistance in apoptosis. Cell Death Differ. 2007 Apr;14(4):872-5.

Ma X, Shah Y, Cheung C, Guo G, Feigenbaum L, Krausz K, Idle J, Gonzalez F. The PREgnane X Receptor Gene-Humanized Mouse: A model for Investigator Drug-Drug Interactions Mediated by Cytochromes P450 3A. Drug Metabolism and Disposition 2007; 35(2): 194-200.

Jochum C, Beste M, Zellmer E, Graves SS, Storb R. CD154 blockade and donor-specific transfusions in DLA-identical marrow transplantation in dogs conditioned with 1-Gy total body irradiation. Biol Blood Marrow Transplant. 2007 Feb;13(2):164-71.

Parmar K, Mauch P, Vergillo JA, Sackstein R, Down J . Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci. March 27, 2007; 104(13):5431-36.

Stegmeier F, Sowa M, Nalepa G, Gygi S, Harper W, Elledge S. The tumor suppressor CYLD regulates entry into mitosis. Proc Natl Acad Sci. May 22, 2007; 104(21):8869-74.

Al-Mutairi DA, Craik JD, Batinic-Haberle I, Benov LT. Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin. Free Radic Res. 2007 Jan;41(1):89-96.

Brush J, Lipnick SL, Phillips T, Sitko J, McDonald JT, McBride WH. Molecular mechanisms of late normal tissue injury. Semin Radiat Oncol. 2007; 17(2):121-30.

Smogorzewska A, Matsuoka S, Vinciguerra P, et al. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell. 2007; 129:289-301.

Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science. 2007;316(5828):1194-8.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science. 2007;316(5828):1160-6.

Chao NJ. Accidental or intentional exposure to ionizing radiation: Biodosimetry and treatment options. Exp Hematol. 2007; 35(4 Suppl 1):24-7.

Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, et al. Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med. 2007; 4(4):e106.

Chute JP, Muramoto GG, Salter AB, Meadows SK, Rickman DW, Chen B, Himburg HA, Chao NJ. Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. Blood. 2007; 109(6):2365-72.

Moulder JE, Cohen EP. Future strategies for mitigation and treatment of chronic radiation-induced normal tissue injury. Semin Radiat Oncol. 2007; 17(2):141-8.

Dertinger SD, Miller RK, Brewer K, Smudzin T, Torous DK, Roberts DJ, Avlasevich SL, Bryce SM, Sugunan S, Chen Y. Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage. Mutat Res: Genet Toxicol Environ Mutagen. 2007; 626(1-2):111-9.

Moulder JE, Cohen EP. Renal dysfunction after total body irradiation: dose-effect relationship: in regard to Kal and van Kempen-Harteveld. Int J Radiat Oncol Biol Phys. 2007; 67(1):319; author reply 319-20.

2006

Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15091-6.

Al-Mutairi DA, Craik JD, Batinic-Haberle I, Benov LT. Photosensitizing action of isomeric zinc N-methylpyridylporphyrins in human carcinoma cells. Free Radic Res. 2006 May;40(5):477-83.

Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Cicciarelli JC. Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes. Transplant Proc. 2006 Dec;38(10):3184-8.

Cavalieri S, Funaro A, Porcedda P, Turinetto V, Migone N, Gatti RA, Brusco A. ATM mutations in Italian families with ataxia telangiectasia include two distinct large genomic deletions. Hum Mutat. 2006 Oct;27(10):1061.

Lakatos HF, Burgess HA, Thatcher TH, Redonnet MR, Hernady E, Williams JP, Sime PJ. Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation. Exp Lung Res. 2006 May;32(5):181-99.

Batinic-Haberle I, Spasojevic I, Stevens RD, Bondurant B, Okado-Matsumoto A, Fridovich I, Vujaskovic Z, Dewhirst MW. New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme. Dalton Trans. 2006 Jan 28;(4):617-24.

Zhang D, Zaugg K,Mak T, Elledge S. A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell. 126. August 11, 2006: 529-542.

Hafer K, Scuric Z, Iwamoto KS, Schiestl RH. Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res. 2006; 165(5):616-20.

Shuryak I, Sachs RK, Hlatky L, Little MP, Hahnfeldt P, Brenner DJ. Radiation-induced leukemia at doses relevant to radiation therapy: modeling mechanisms and estimating risks. J Natl Cancer Inst. 2006; 98(24):1794-806.

Mielcarek M, Georges GE, Storb R. Denileukin diftitox as prophylaxis against graft-versus-host disease in the canine hematopoietic cell transplantation model. Biol Blood Marrow Transplant. 2006; 12(9):899-904.

Greenberger JS. Could gene therapy prevent the effects of irradiation exposure? Pharmacogenomics. 2006; 7(8):1141-5.

Kagan VE, Tyurina YY, Bayir H, Chu CT, Kapralov AV, Vlasova II, Belikova NA, Tyurin VA, Amoscato A, Epperly M, Greenberger J, DeKosky S, Shvedova AA, Jiang J. The "pro-apoptotic genies" get out of mitochondria: oxidative lipidomics and redox activity of cytochrome c/Cardiolipin complexes. Chem Biol Interactions. 2006; 163(1-2):15-28.

Belikova NA, Vladimirov YA, Osipov AN, Kapralov AA, Tyurin VA, Potapovich MW, Basova LV, Peterson J, Kurnikov IV, Kagan VE. Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes. Biochemistry. 2006; 45(15):4998-5009.

Vlasova II, Tyurin VA, Kapralov AA, Kurnikov IV, Osipov AN, Potapovich MV, Stoyanovsky DA, Kagan VE. Nitric oxide inhibits peroxidase activity of cytochrome c.cardiolipin complex and blocks cardiolipin oxidation. J Biol Chem. 2006; 281(21):14554-62.

Tyurina YY, Kini V, Tyurin VA, Vlasova II, Jiang J, Kapralov AA, Belikova NA, Yalowich JC, Kurnikov IV, Kagan VE. Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and anti-apoptotic functions of etoposide. Mol Pharmacol. 2006; 70(2):706-17.

Bayir H, Fadeel B, Palladino MJ, Witasp E, Kurnikov IV, Tyurina YY, Tyurin VA, Amoscato AA, Jiang J, Kochanek PM, DeKosky ST, Greenberger JS, Shvedova AA, Kagan VE. Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. Biochim Biophys Acta. 2006; 1757(5-6):648-59.

Z Xiao, Y Su, S Yang, L Yin, W Wang, Y Yi, BM Fenton, L Zhang, P Okunieff. Protective effect of Esculentoside-A on radiation-induced dermatitis and fibrosis. J Radiat Oncol Biol Phys. 2006; 65(3):882-9.

P Okunieff, J Xu, D Hu, W Liu, L Zhang, G Morrow, A Pentland, J Ryan, I Ding. Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines. Int J Radiat Oncol Biol Phys. 2006; 65(3):890-898.

Frank Pajonk F, Anja Riedisser A, Henke M, McBride WH, Fiebich B. The effects of tea extracts on proinflammatory signaling. BMC Med. 2006; 4:28.

Liu W-C, Wang S-C, Tsai M-L, Chen M-C, Wang Y-C, Hong J-H, McBride WH, Chiang, C-S. Protection against Radiation-Induced Bone Marrow and Intestinal Injuries by Cordyceps sinensis, a Chinese Herbal Medicine. Radiat Res. 2006; 166:900–907.

Goldstine JV, Nahas S, Gamo K, Gartler SM, Hansen RS, Roelfsema JH, Gatti RA, Marahrens Y. Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with IGF syndrome without downstream kinase activity. DNA Repair. 2006; 5:432-43.

OA Hatoum, MF Otterson, D Kopelman, H Miura, I Sukhotnik, BT Larsen, RM Selle, JE Moulder, DD Gutterman.  Radiation Induces Endothelial Dysfunction in Murine Intestinal Arterioles via Enhanced Production of Reactive Oxygen Species. Arterioscler Thromb Vasc Biol. 2006; 26:287-294.

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Last Updated March 06, 2014